CAS: 4353-77-9; Trimethylsilyl Sulfochloridate

上下游产品

chloro-trimethyl-silane bis(trimethylsilyl)sulphate Bis(trimethylsilyl)peroxodisulfat sulfur trioxidetrimethylsilyl methanesulfonate -benzoldisulfonat1,4-Bis--benzoldisulfonat 4-Trimethylsilyl-benzolsulfonsaeure-trimethylsilylester 1,1,3,3-tetramethyl-1,3-dicyclohexyldisiloxane

📜三甲基氯硅烷置于三氧化硫体系中,化学反应 0.17H,以87%的收率获得产物三甲基甲硅烷
参考文献:三氧化硫插入苯胺基三甲基硅烷的 N-Si 键.一种制备游离苯胺基硫酸的改进方法
标题:三氧化硫插入苯胺基三甲基硅烷的 N-Si 键.一种制备游离苯胺基硫酸的改进方法
摘要:研发了苯胺基三甲基硅烷 (1) 与多种磺化剂 [so3,Clso3H,氯硫酸三甲基甲硅烷基酯 (5),二恶烷-三氧化硫复合物,氯硫酸乙酯 (10)] 之间的反应.使用 So3,5 或二恶烷-三氧化硫络合物,将三氧化硫分子选择性地插入到 1 的 N-Si 键中,反应生成苯酰胺硫酸三甲基甲硅烷酯 (2),用乙酸,三氟乙酸或甲醇处理后得到游离的苯酰胺硫酸酸(3).1与clso3H反应直接得到3,但产物被少量硫酸氢苯胺和氯化苯胺污染.1与10的反应产生含有二苯胺(4-磺基苯基酰胺基)硫酸盐,4-氨基苯磺酸和苯基酰胺基硫酸乙酯作为主要产物(脱甲硅烷基化后)的混合物.
DOI:10.1246/bcsj.59.2517

专利信息

专利号:US-2009099200-A1
优先权日:2005-06-09
标题 :Azacyclohexane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase
发明人：LI CHUN SING; RAMTOHUL YEEMAN K; HUANG ZHENG; LACHANCE NICOLAS
权利人:LI CHUN SING; RAMTOHUL YEEMAN K; HUANG ZHENG; LACHANCE NICOLAS
摘要:Azacyclohexane derivatives of structural formula I are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and liver steatosis.

专利号:US-5151431-A
优先权日:1989-06-26
标 题:4,5-dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid derivatives useful for treating hypertension or edema
发明人：INABA HITOSHI; NISHIJIMA KAZUMI; KATO KAZUO; YAMAMOTO ICHIRO; MOCHIDA EI; OHTOMO KIKUO
权利人:MOCHIDA PHARM CO LTD; HODOGAYA CHEMICAL CO LTD
摘要:The present invention relates to novel 4,5-dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid compounds, processes for producing said compounds, intermediate compounds, i.e. novel 4,5-dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one compounds and 4,5-dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime compounds in the synthesis of said compounds, processes for producing said intermediate compounds, and pharmaceutical or veterinary compositions containing said compounds. The present invention is based on the selection of the substituents of 4,5-dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid compounds at 2-position, namely 2-(2-penten-3-yl)-, 2-cyclohexyl-, 2-naphthyl-, 2-thienyl-, etc. The compounds of the present invention containing these substituents have potent hypotensive, anti-oedematous and diuretic effects as well as an activity of removing ascites. The compounds of the present invention are extremely useful for treatment of diseases and disorders mentioned above.

专利号:US-12084554-B2
优先权日:2017-04-10
标 题 :Polyphenylenes, methods, and uses thereof
发明人：HOLDCROFT STEVEN; SKALSKI THOMAS J G; ADAMSKI MICHAEL; BRITTON BENJAMIN; PECKHAM TIMOTHY J
权利人:UNIV FRASER SIMON
摘要:Described herein are anionic phenylene oligomers and polymers, and devices including these materials. The oligomers and polymers can be prepared in a convenient and well-controlled manner, and can be used in cation exchange membranes. Also described is the controlled synthesis of anionic phenylene monomers and their use in synthesizing anionic oligomers and polymers, with precise control of the position and number of anionic groups.