CAS: 403-21-4; 3-Fluoro-4-Nitrobenzoic Acid

上下游产品

CAS号446-34-4 3-氟-4-硝基甲苯 | CAS号503315-74-0 (3-氟-4-硝基苯基)甲醇 | CAS号86790-39-8 methyl 2-(3-flu... | CAS号578-46-1 5-甲基-2-硝基苯胺 | CAS号5081-36-7 3-甲氧基-4-硝基苯甲酸 | CAS号41263-74-5 4-甲氨基-3-硝基苯甲酸 | CAS号455-87-8 4-氨基-3-氟苯甲酸 | CAS号14617-29-9 3-(Benzyloxy)-4... | CAS号503315-74-0 (3-氟-4-硝基苯基)甲醇 | CAS号214778-10-6 3-(甲基氨基)-4-硝基苯甲酸 | CAS号658700-15-3 (3-fluoro-4-nit... | CAS号2369-13-3 3-氟-4-硝基苯胺 | CAS号157665-53-7 4-氨基-3-氟苯甲酸叔丁酯 | CAS号157665-52-6 3-氟-4-硝基苯甲酸叔丁酯

(3-氟-4-硝基苯基)甲醇置于jones Reagent,Calcium Carbonate体系中,用 水,丙酮 作为反应溶剂,化学反应 0.5H,以92%的收率获得产物3-氟-4-硝基苯甲酸
参考文献: 4-Phenyl-Pyrimido [4,5-B] Indole Derivatives[fr] Derives 4-Phenyl-Pyrimido [4,5-B]Indoles
标题: 4-Phenyl-Pyrimido [4,5-B] Indole Derivatives[fr] Derives 4-Phenyl-Pyrimido [4,5-B]Indoles
摘要:本发明涉及4-苯基-吡咯并[4,5-B]吲哚,它们可用作药物制剂的活性成分.本发明的4-苯基-吡咯并[4,5-B]吲哚具有mkk7和mkk4的抑制活性,可用于预防和治疗与mkk7和mkk4活性相关的疾病.这些疾病包括炎症和免疫调节紊乱疾病,如哮喘,特应性皮炎,鼻炎,过敏性鼻炎,过敏性疾病,慢性阻塞性肺病,脓毒性休克,关节炎,关节疾病和心肌损伤,以及风湿性关节炎,格氏病和动脉粥样硬化等自身免疫病理病变,还可用于缺血,心肌损伤,肺动脉高压,肾功能衰竭,亨廷顿舞蹈症和心脏肥大的治疗,以及帕金森病,阿尔茨海默病和局灶性缺血等神经退行性疾病.

专利信息

专利号:US-11773118-B2
优先权日:2019-02-21
标 题:Methods of making high enantioselective secondary alcohols
发明人：YU CHENG-DER TONY; HSIEH YIH-HUANG; LIN SHU-YI; CHAO CHIN-SHENG; HSIEH YIN-CHENG; LAI MING-TAIN
权利人:OBI PHARMA INC
摘要:A new process to synthesis of compound OBI-3424 R-form and S-form products is provided. The “R-formâ€? compound OBI-3423 was first synthesized with 48% overall yield from compound OBI-3424-5 by installation of the labile phosphate motif at later stage. The stereo chemistry is established by 5 steps chemo-enzyme combination synthesis to afford 99% optical purity. After then, the “S-formâ€? compound OBI-3424 is prepared with improving overall yield of 54% from compound OBI-3424-5. The stereo chemistry is established by 4 steps combination of chemo-enzyme synthesis with excellent optical purity of 99%.

专利号:US-2005100968-A1
优先权日:2000-02-23
标题 :Self-encoded combinatorial synthesis of compound multiplets
发明人：GALLOP MARK A; DOWER WILLIAM J; BARRETT RON W
权利人:XENOPORT INC
摘要:The present invention provides a variety of methods for synthesizing, encoding and decoding compounds in a combinatorial library. One step or cycle in the synthetic methods of the invention is a self-encoding step in which different pairs of components, each pair with a known and different molecular weight difference, are reacted with supports, whereby two compounds differing in molecular weight are formed on each support. The molecular weight difference between the two compounds on the support encodes for a particular component pair. Libraries of compounds formed according to the methods of the invention are also provided.

专利号:EP-1259823-A2
优先权日:2000-02-23
标题 :Self-encoded combinatorial synthesis of compound multiplets

专利号:WO-0162772-A2
优先权日:2000-02-23
标 题:Self-encoded combinatorial synthesis of compound multiplets

专利号:US-4629811-A
优先权日:1982-05-03
标 题:3-sulfonylamino-4-aminobenzophenone derivatives
发明人：DOMINIANNI SAMUEL J
权利人:LILLY CO ELI
摘要:A process is provided which produces 3-sulfonylamino-4-aminobenzophenone intermediates useful in the regiospecific synthesis of benzimidazole antiviral agents.

专利号:CN-113666887-B
优先权日:2021-09-18
标 题 :A kind of 1,4-naphthoquinone derivative, synthesis method and application