CAS: 2817-71-2; 1-Ethylpyrazole

相似化合物

10199-67-4 32500-67-7 96450-53-2

上下游产品

CAS号288-13-1 吡唑 | CAS号74-96-4 溴乙烷 | CAS号75-03-6 碘乙烷 | CAS号304903-10-4 1-乙基-1H-吡唑-4-甲醛 | CAS号902837-62-1 1-乙基-1H-吡唑-5-甲醛 | CAS号288-13-1 吡唑 | CAS号54509-73-8 ethene | CAS号71229-85-1 4-溴-1-乙基-1H-吡唑

1-乙烯基吡唑 反应生成1-乙基-吡唑
参考文献:Skvortsova G. G.; Domnina E. S.; Shestova L. A.; Bopohob V. K.; Kejko V. +,Ximiya Geterotsikl. Soedin.,1976,Ho 9,1247-1251
标题:Skvortsova G. G.; Domnina E. S.; Shestova L. A.; Bopohob V. K.; Kejko V. +,Ximiya Geterotsikl. Soedin.,1976,Ho 9,1247-1251

专利信息

专利号:WO-2017082924-A1
优先权日:2015-11-13
标题 :Peptide and peptide mimetic binding antagonists of polo-like kinase 1 polo box domain and methods of use
发明人：BURKE TERRENCE R JR; HYMEL DAVID
权利人:THE US SECRETARY DEPT OF HEALTH & HUMAN SERVICES
摘要:The description provides novel compounds that may serve as anticancer therapeutics. The compounds of the description bind to polo-like kinases through the polo-box domain. The peptide derivatives of the description have achieved improved efficacy in biochemical assays against Plk1. The description also provides methods of use, methods of preparation, compositions, and kits thereof. Further, the description provides a novel method of design and/or synthesis of phosphoryl-derived peptide derivatives useful as therapeutic agents.

专利号:US-10905769-B2
优先权日:2015-11-13
标 题:Peptide and peptide mimetic binding antagonists of polo-like kinase 1 polo box domain and methods of use
发明人：BURKE JR TERRENCE R; HYMEL DAVID T; TSUJI KOHEI
权利人:THE US SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES
摘要:The description provides novel compounds that may serve as anticancer therapeutics. The compounds of the description bind to polo-like kinases through the polo-box domain. The peptide derivatives of the description have achieved improved efficacy in biochemical assays against Plk1. Exemplary compounds of the description include macrocyclic peptidomimetics with high affinity and selectivity for polo-like kinases, which may provide the basis for a new genre of anticancer therapeutics. Other exemplary compounds of the description include bi-valent compounds with that bind to polo-like kinases through both kinase domain and polo-box domain simultaneously by incorporating additional moieties that target Plk1 kinase domain, which significantly enhances affinitity relative and may provide the basis for a new genre of anticancer therapeutics. The description also provides methods of use, methods of preparation, compositions, and kits thereof. Further, the description provides a novel method of design and/or synthesis of phosphoryl-derived peptide derivatives useful as therapeutic agents.

专利号:US-9936723-B2
优先权日:2014-02-12
标题 :Process for the synthesis of substituted 1-benzyl-3-(1-(isoxazol-4-ylmethyl)-1h-pyrazol-4-yl)imidazolidine-2,4-diones
发明人：FOTSING JOSEPH R
权利人:SENOMYX INC
摘要:The present invention relates to processes and intermediates for the preparation of compounds of formula (I): n nor a salt or oxide thereof, wherein Alk, M1, M2, R1, R2, R3, R4, R5, R6, R7, and n are as described herein. The present invention also relates to compounds of formula (I) and composition comprising a compound of formula (I). Also disclosed is a method of altering or improving the taste of a composition that includes adding to the composition at least one compound of formula (I), in an amount effective to obtain a modified composition having altered or improved taste relative to an otherwise identical composition lacking said compound.

专利号:US-12054833-B2
优先权日:2020-07-29
标 题:Catalyst for synthesizing organic carbonate and method of producing thereof, electrode for synthesizing organic carbonate, cell for synthesizing organic carbonate, method of producing organic carbonate, and synthesis system
发明人：FUJINUMA NAOHIRO
权利人:SEKISUI CHEMICAL CO LTD
摘要:An organic carbonate synthesis catalyst for electrochemically synthesizing an organic carbonate from carbon monoxide, comprises: an active particle containing a metal element; and a porous carbon supporting the active particle.

专利号:CN-109382140-B
优先权日:2018-11-13
标 题 :Carboxyl-functionalized pyrazole ionic liquid, synthesis method and method for catalyzing synthesis of cyclic carbonate with the same

专利号:CN-109382140-A
优先权日:2018-11-13
标题 :Carboxyl-functionalized pyrazole ionic liquid, synthesis method and method for catalyzing synthesis of cyclic carbonate with the same