专利号:US-2025236694-A1 优先权日:2024-01-19 标 题:Synthesis of highly branched polymers via high throughput screening 发明人:XU MIZHI; IWASO KAZUHISA; SHANNON DECLAN; BATES MORGAN W; WANG HENGBIN; CHATANI SHUNSUKE; HAWKER CRAIG J 权利人:UNIV CALIFORNIA; THE MITSUBISHI CHEMICAL CORP 摘要:Efficient condition optimization for the synthesis of highly branched polymers using high throughput screening has been developed. This innovation allows rapid production of soluble, highly branched polymers with different properties (molecular weight, degree of branching, etc.). Moreover, this versatile technique has the potential to be extended to other monomer/linker systems and polymerization techniques such as emulsion or suspension polymerization, anionic polymerization and continuous flow synthesis. A resin composition is further disclosed.
专利号:WO-2023102600-A1 优先权日:2021-12-06 标题:Synthesis of amphiphilic block copolymers and polymeric nanofibers produced therefrom 发明人:ZETTERLUND PER B; ISHIZUKA FUMI; KIM HYUN JIN; CHATANI SHUNSUKE; NIINO HIROSHI 权利人:NEWSOUTH INNOVATIONS PTY LTD 摘要:The present disclosure relates to the field of synthesis of block copolymers, and polymeric nanofibers having a core-shell morphology produced therefrom. The present disclosure relates to the field of synthesis of block copolymers where one block is more hydrophobic than the other block and is a different composition. The disclosure also relates to uses of these polymeric nanofibers in various applications, such as reinforcing a polymeric matrix and for coatings applications.
专利号:US-2024269636-A1 优先权日:2021-06-14 标题:Ultra-high throughput on-chip synthesis of microgels with tunable mechanical properties 发明人:LEE DAEYEON; ISSADORE DAVID AARON; WU JINGYU; YADAVALI SAGAR PRASAD 权利人:UNIV PENNSYLVANIA 摘要:Hydrogel particles (microgels) generated using microfluidic methods have superb properties such as high size uniformity and precise control over degradation and release profiles, making them useful for applications in wound healing and injectable drug delivery. However, the throughput of microfluidics is constrained by the physics governing the flow of immiscible fluids confined within microchannels. This throughput tends to be several orders of magnitude lower than what would be necessary for commercial and clinical applications. Here, we demonstrate the scaling up of on-chip synthesis of microgels by parallelizing the microfluidic channels. Taking advantage of the established fabrication technologies developed by the semiconductor industry and a high flow control system, a 4-inch silicon microfluidic chip integrating more than 4,000 microfluidic devices is developed. By incorporating a high energy flood UV source, this chip allows the synthesis of poly (ethylene glycol) diacrylate microgel particles with diameter down to 30 m at a throughput above Ikg/hr. By using photomasks that enable milli-second scale control of the UV exposure, the stiffness of microgels can be varied.
专利号:US-7767425-B2 优先权日:2001-11-16 标 题:Enzymatic synthesis of sugar acrylates 发明人:BOECKH DIETER; HAUER BERNHARD; HAERING DIETMAR 权利人:BASF AG 摘要:A process is described for the enzymatic synthesis of sugar acrylates, and a process is described for preparing polymeric sugar acrylates, the polymers obtainable by this process and their use for preparing, for example, cosmetics, drugs, laundry detergents, thickeners, protecting colloids, superabsorbents and textile sizes.
专利号:US-4133942-A 优先权日:1972-11-06 标题:Polymeric carrier for a controlled synthesis of peptides and the method of its preparation 发明人:COUPEK JIRI; GUT VLADIMIR 权利人:CESKOSLOVENSKA AKADEMIE VED 摘要:An acrylic polymer gel suitable for use as a carrier in the controlled synthesis of polypeptides is provided. The polymer comprises a diazotized terpolymer of the condensation product of a monomer selected from the group consisting of hydroxyalkyl acrylates and hydroxyalkyl methacrylates, a polyfunctional cross-linking monomer selected from the group consisting of alkylene diacrylates, alkylene dimethacrylates, polyacrylates and polymethacrylates of polyalcohols, alkylene bisacrylamides and divinylbenzene, and an aromatic ring-containing compound selected from the group consisting of aromatic acids and their anhydrides and chlorides, aromatic isocyanates, halogenophenylsilanes, and aromatic epoxy compounds. The condensate has its aromatic rings chlormethylated. The first monomer and the polyfunctional cross-linking monomer are copolymerized and the resultant copolymer is condensed with said compounds which contain an aromatic ring.
专利号:US-4079021-A 优先权日:1972-11-06 标 题:Polymeric carrier for a controlled synthesis of peptides 发明人:COUPEK JIRI; GUT VLADIMIR 权利人:CESKOSLOVENSKA AKADEMIE VED 摘要:An acrylic polymer suitable for use as carrier in the controlled synthesis of polypeptides is provided. The polymer comprises the condensation product of a monomer selected from the group consisting of hydroxyalkyl acrylates and hydroxyalkyl methacrylates, a polyfunctional cross-linking monomer selected from the group consisting of alkylene diacrylates, alkylene dimethacrylates, polyacrylates and polymethacrylates of polyalochols, alkylene bisacrylamides and divinylbenzene, and an aromatic ring-containing compound selected from the group consisting of aromatic acids and their anhydrides and chlorides, aromatic isocyanates, halogenophenylsilanes, and aromatic epoxy compounds. The condensate has its aromatic rings chlormethylated. The first monomer and the polyfunctional cross-linking monomer are copolymerized and the resultant copolymer is condensed with said compounds which contain an aromatic ring.
摘要:Xu, Z.; Bratlie, K. M., Science of Synthesis, (2021) , 565. 摘要:Toxicology and Applied Pharmacology., 28(313), 1974 [] 摘要:Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases., 24(4)(58), 1980