CAS: 155899-66-4; (3Ar,4S,6R,6As)-6-Amino-2,2-Dimethyltetrahydro-3Ah-Cyclopenta[d][1,3]Dioxol-4-Ol

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CAS号155855-51-9 (3AS,4S,7R,7AS)... | CAS号380307-23-3 (1S,2R,3S,4R)-4... | CAS号345898-95-5 N-(((4S,5R)-2,2... | CAS号38838-06-1 (3aS,4S,6R,6aR)... | CAS号60410-16-4 (1R,4S)-4-羟基环戊-... | CAS号542-92-7 环戊二烯 | CAS号274693-27-5 替卡格雷 | CAS号274693-55-9 1-金刚烷甲基酮中间体 | CAS号274693-53-7 N-[(3aS,4R,6S,6...

Cis-3,5-二乙酰氧基-1-环戊烯置于disodium Hydrogenphosphate,四氧化锇,Sodium Hydride,对甲苯磺酸,一水合肼,N-甲基吗啉氧化物体系中,用 四氢呋喃,乙醇,水,丙酮,Mineral Oil,叔丁醇 用作溶剂,化学反应 60.0H,反应生成(3Ar,4S,6R,6As)-6-氨基四氢-2,2-二甲基-4H-环戊烯并-1,3-二氧杂环戊烷-4-醇
参考文献: Improved Processes For Preparing Pure (3Ar,4S,6R,6As)-6-Amino-2,2-Dimethyltetrahdro-3Ah-Cyclopenta[d] [1,3]-Dioxol-4-Ol And Its Key Starting Material[fr] Procédés Améliorés De Préparation De (3Ar,4S,6R,6As)-6-Amino-2,2-Diméthyltétrahdro-3Ah-Cyclopenta[d] [1,3]-Dioxol-4-Ol Pur Et Son Matériau De Départ Clé
标题: Improved Processes For Preparing Pure (3Ar,4S,6R,6As)-6-Amino-2,2-Dimethyltetrahdro-3Ah-Cyclopenta[d] [1,3]-Dioxol-4-Ol And Its Key Starting Material[fr] Procédés Améliorés De Préparation De (3Ar,4S,6R,6As)-6-Amino-2,2-Diméthyltétrahdro-3Ah-Cyclopenta[d] [1,3]-Dioxol-4-Ol Pur Et Son Matériau De Départ Clé

专利信息

专利号:US-9469614-B2
优先权日:2011-10-27
标 题:Synthesis of triazolopyrimidine compounds
发明人：ZUPANCIC BORUT; MARAS NENAD; STERK DAMJAN
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.

专利号:EP-2607355-A1
优先权日:2011-12-23
标 题:Synthesis of triazolopyrimidine compounds
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.

专利号:EP-2666771-A1
优先权日:2012-05-24
标题 :Synthesis of Aminocyclopentanetriol Derivatives
发明人：STERK DAMJAN; CASAR ZDENKO
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor. nThe present invention provides in particular a process for the preparation of a compound of formula Vn ncomprising: na) providing a compound of formula IVn n, and nb) reducing the compound of formula IV with activated zinc in the presence of copper to give the compound of formula V.

专利号:US-9278972-B2
优先权日:2011-12-23
标题 :Synthesis of triazolopyrimidine compounds
发明人：MARAS NENAD; GAZIC SMILOVIC IVANA; STERK DAMJAN
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.

专利号:US-9221829-B2
优先权日:2011-09-14
标题:Synthesis of triazolopyrimidine compounds
发明人：MARAS NENED; ZUPANCIC BORUT
权利人:MARAS NENED; ZUPANCIC BORUT; LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives, suitable for the preparation of Ticagrelor (TCG).

专利号:EP-2570405-A1
优先权日:2011-09-14
标题:Synthesis of Triazolopyrimidine Compounds
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the filed of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives, suitable for the preparation of ticagrelor (TGC)