CAS: 1280210-79-8; Tert-Butyl 4,6-Dihydropyrrolo[3,4-C]Pyrazole-5(2H)-Carboxylate

相似化合物

157327-47-4 657428-42-7 1419101-29-3

上下游产品

CAS号157327-42-9 3-((二甲基氨基)亚甲基)-... | CAS号101385-93-7 1-叔丁氧碳基-3-吡咯烷酮

专利信息

专利号:US-9527855-B2
优先权日:2011-06-29
标题:Process for preparing chiral dipeptidyl peptidase-IV inhibitors
发明人：ZACUTO MICHAEL J; DUNN ROBERT F; MOMENT AARON J; JANEY JACOB M; LIEBERMAN DAVID; SHEEN FAYE; BREMEYER NADINE; SCOTT JEREMY; KUETHE JEFFREY T; TAN LUSHI; CHEN QINGHAO
权利人:MERCK SHARP & DOHME; MERCK SHARP & DOHME
摘要:A process for the preparation of pyrazolopyrolidines of structural formula I: n nand W isn n nor P, wherein in P is an amine protecting group. These compounds are useful in the synthesis of dipeptidyl peptidase-IV inhibitors for the treatment of Type 2 diabetes. Also provided are useful intermediates obtained from the process.

专利号:US-9944644-B2
优先权日:2013-03-14
标 题 :Octahydropyrrolopyrroles their preparation and use
发明人：PETRUKHIN KONSTANTIN; CIOFFI CHRISTOPHER; JOHNSON GRAHAM; DOBRI NICOLETA; FREEMAN EMILY; CHEN PING; CONLON MICHAEL; ZHU LEI
权利人:PETRUKHIN KONSTANTIN; CIOFFI CHRISTOPHER; JOHNSON GRAHAM; DOBRI NICOLETA; FREEMAN EMILY; CHEN PING; CONLON MICHAEL; ZHU LEI; UNIV COLUMBIA
摘要:The present invention provides compounds comprising variously substituted octahydropyrrolopyrroles, their synthesis, methods of making, methods of using, compositions and formulations thereof.