CAS: 83356-02-9; 2,4,6-Trimethoxy-5-Nitropyrimidine

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    CAS号13106-85-9 2,4,6-三甲氧基嘧啶 | CAS号67-56-1 甲醇 | CAS号4359-87-9 5-硝基-2,4,6-三氯嘧啶

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      📜2-氯-4,6-二甲氧基嘧啶置于硝酸,Sodium Hydride,三氟乙酸酐体系中,用 二氯甲烷,Mineral Oil 作为反应溶剂,化学反应 1.0H,反应生成 2,4,6-三甲氧基-5-硝基嘧啶
      参考文献:1,2,3',5'-Tetrahydro-2'H-Spiro[indole-3,1'-Pyrrolo[3,4-C]Pyrrole]-2,3'-Dione Compounds As Therapeutic Agents Activating Tp53
      标题:1,2,3',5'-Tetrahydro-2'H-Spiro[indole-3,1'-Pyrrolo[3,4-C]Pyrrole]-2,3'-Dione Compounds As Therapeutic Agents Activating Tp53
      摘要:该发明涉及由式(I)表示的1,2,3',5'-四氢-2'H-螺[吲哚-3,1'-吡咯[3,4-C]吡咯]-2,3'-二酮化合物,其中所有符号和变量如描述中所定义.这些化合物可用于预防和/或治疗来自癌症,免疫疾病,炎症症状,与过度增殖相关的过敏性皮肤疾病,致盲疾病和病毒感染的疾病组中选择的方法.

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      主要参考文献

      参考标题:Electrophilic Tetraalkylammonium Nitrate Nitration. Ii. Improved Anhydrous Aromatic And Heteroaromatic Mononitration With Tetramethylammonium Nitrate And Triflic Anhydride, Including Selected Microwave Examples
      作者:Scott A. Shackelford,Mark B. Anderson,Lance C. Christie,Thomas Goetzen,Mark C. Guzman,Martha A. Hananel,Wayne D. Kornreich,Haitao Li,Ved P. Pathak,Alex K. Rabinovich,Ranjan J. Rajapakse,Larry K. Truesdale,Stella M. Tsank,Haresh N. Vazir |发布日期:2003.1.1
      摘要:A New One-Pot Nitration Employing Tetramethylammonium Nitrate And Trifluoromethanesulfonic Anhydride In Dichloromethane To Provide A Ready Source Of The Nitronium Triflate Nitrating Agent Is Presented. Rapid And Selective Nitration With A Variety Of Aromatic And Heteroaromatic Substrates Is Achieved Resulting In The Synthesis Of Several Novel Organic Compounds. A Distinct Advantage Is The Removal Of

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      摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 335.
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