CAS: 765-58-2; 2-Bromo-5-Methylthiophene

该化合物是一种溴化硫苯衍生物,在5号位置有甲基替代成分,作为有机合成的多用途中间体,其反应性溴元素能够产生高效的交叉反应,如铃木或静态联动,因此对于构建复杂的环环环框架很有价值.甲基组在允许进一步功能化的同时增强稳定性.该化合物在制药,农用化学品和材料科学中特别有用,因为它与多种反应条件相容.高纯度能确保要求应用的性能一致.其定义明确的结构和再活性特征使得开发硫磷化合物的研究人员更愿意选择它.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号554-14-3 2-甲基噻吩 | CAS号3141-27-3 2,5-二溴噻吩 | CAS号74-88-4 碘甲烷 | CAS号56-23-5 四氯化碳 | CAS号128-08-5 N-溴代丁二酰亚胺 | CAS号506-68-3 溴化氰 | CAS号146796-00-1 2-bromo-5-(5-me... | CAS号26905-73-7 2-methyl-5-(5-t... | CAS号1918-79-2 5-甲基-2-噻吩甲酸 | CAS号19432-69-0 5-甲基噻吩-2-羧酸甲酯 | CAS号72835-25-7 5-甲基噻吩-2-甲腈 | CAS号638-02-8 2,5-二甲基噻吩 | CAS号638-00-6 2,4-二甲基噻吩 | CAS号134135-41-4 5-溴甲基噻吩-2-甲腈 | CAS号32358-94-4 5-(5-甲基噻吩-2-基)噻... | CAS号172872-73-0 (4-溴-3,5-二甲基噻吩-...

合成工艺路线路线简述

    2-甲基噻吩置于n-溴代丁二酰亚胺(Nbs),高氯酸体系中,用84%的收率获得产物2-溴-5-甲基噻吩
    参考文献:Functionalization Of Photochromic Dithienylmaleimides
    标题:Functionalization Of Photochromic Dithienylmaleimides
    摘要:报道了在三个不同位置对光致变色二噁英基马来酰亚胺进行官能化的合成路线.
    DOI:10.1039/c5Ra00015G

    专利信息


    专利号:US-8450503-B2
    优先权日:2002-08-09
    标题:Photochromic and electrochromic compounds and methods of synthesizing and using same
    发明人:BRANDA NEIL R; PETERS ANDREA; WIGGLESWORTH ANTHONY J
    权利人:BRANDA NEIL R; PETERS ANDREA; WIGGLESWORTH ANTHONY J; SWITCH MATERIALS INC
    摘要:This invention relates to novel photochromic and electrochromic monomers and polymers based on 1,2-dithienylcyclopentene derivatives and method of using and synthesizing same. The compounds are reversibly interconvertible between different isomeric forms under suitable photochromic or electrochromic conditions. The electrochromic conversion may be catalytic. The application also relates to ultra-high density homopolymers prepared using ring-opening methathesis polymerization (ROMP) where the central ring of the 1,2-bis(3-thienyl)-cyclopentene is incorporated directly into the polymer backbone. The monomer units may be readily functionalized to enable the synthesis of polymers with diverse structural and electronic properties. The compounds have many potential applications including high-density optical information storage systems, photoregulated molecular switches, reversible holographic systems, ophthalmic lenses, actinometry and molecular sensors, photochromic inks, paints and fibers and optoelectronic systems such as optical waveguides, Bragg reflectors and dielectric mirrors.

    专利号:US-9663594-B2
    优先权日:2014-05-15
    标 题 :Synthesis of aryl coupled bis phenoxides and their use in olefin polymerization catalyst systems with activator-supports
    发明人:HLAVINKA MARK L
    权利人:CHEVRON PHILLIPS CHEMICAL CO LP; CHEVRON PHILIPS CHEMICAL COMPANY LP
    摘要:Disclosed herein are methods of making bis(phenol) ligand compounds and transition metal bis(phenolate) compounds. The transition metal bis(phenolate) compounds can be used as components in catalyst systems for the polymerization of olefins.

    专利号:US-2021074930-A1
    优先权日:2019-09-06
    标题 :Synthesis of ft4-based organic semiconducting small molecules by pd-catalyzed direct (hetero)arylation or direct alkenylation
    发明人:HE MINGQIAN; LI YANG; SUN JING; WANG HONGXIANG; ZHOU MONG-DONG
    权利人:CORNING INC; UNIV LIAONING SHIHUA
    摘要:A method for forming organic semiconducting materials, including: providing a mixture having: a tetrathienoacene (FT4)-based monomer, and one of a thiophene-containing compound or an alkene-containing compound; and reacting the FT4-based monomer with the thiophene-containing compound or the alkene-containing compound in a one-step direct arylation reaction mechanism to form a final FT4-based organic semiconducting compound.

    专利号:US-7129361-B2
    优先权日:1998-04-15
    标 题 :Thienylazolylalkoxyethanamines, their preparation and their application as medicaments
    发明人:MERCE-VIDAL RAMON; ANDALUZ-MATARO BLAS; FRIGOLA-CONSTANSA JORDI
    权利人:ESTEVE LABOR DR
    摘要:The thienylazolylalkoxyethanamines (I) where R1 is a hydrogen atom, a halogen atom or a lower alkyl radical; R2, R3 and R4 represent, independently, a hydrogen atom or a lower alkyl radical; and Az represents a five-member nitrogenated hetercyclic aromatic group, N-methyl-substituted, that contains from one to three nitrogen atoms. They have analgesic activity in mammals, including humans. The compounds (I) can be obtained, for example, by reaction of a derivative of hydroxy-thienylazol (IV) with a derivative of a suitable N-(ethyl)amine. The compounds (IV) are useful intermediates in the synthesis of the compounds (I). The compounds (I) have an application in human and/or veterinary medicine.

    专利号:WO-2006127595-A1
    优先权日:2005-05-23
    标题:5-aminopyrazole carboxylic acid derivatives and methods of treatment of metabolic-related disorders thereof
    发明人:SKINNER PHILIP J; SEMPLE GRAEME; WEBB PETER
    权利人:ARENA PHARM INC; SKINNER PHILIP J; SEMPLE GRAEME; WEBB PETER
    摘要:The present invention relates to certain pyrazole carboxylic acid or ester derivatives of Formula (I) and pharmaceutically acceptable salts thereof which exhibit useful pharmacological properties, for example, as agonists for the GPCR referred to herein as RUP38. Also provided by the present invention are pharmaceutical compositions containing compounds of the invention, and methods of using the compounds and compositions of the invention in the treatment of metabolic-related disorders, such as, dyslipidemia, atherosclerosis, coronary heart disease, insulin resistance, type 2 diabetes, Syndrome-X and the like. In addition, the present invention also provides for the use of the compounds of the invention in combination with other active agents such as those belonging to the class of -glucosidase inhibitors, aldose reductase inhibitors, biguanides, HMG-CoA reductase inhibitors, squalene synthesis inhibitors, fibrates, LDL catabolism enhancers, angiotensin converting enzyme (ACE) inhibitors, insulin secretion enhancers and the like.

    专利号:US-11401284-B2
    优先权日:2018-08-30
    标题:Organic semiconducting material and its synthesis and organic semiconducting component with the material
    发明人:MIRLOUP ANTOINE; D'SOUZA DANIEL; FITZNER ROLAND; GERDES OLGA; HILDEBRANDT DIRK; MATTERSTEIG GUNTER; WEISS ANDRE
    权利人:HELIATEK GMBH
    摘要:New absorbing materials of formula (I) for use in organic semiconducting components:
    三晶新材料科技(泰州)有限公司
    ⚠️ 未注册 · 未认证企业
    ⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
    数据来源于公开网络搜索,平台未作核实,请自行辨别。
    🏢敬请 企业认领
    🏬开设公司展台
    📢获取免费会员权益
    🎖️点亮专属注册企业标签
    📇展现公司完整信息 样本查看立即注册认领 →
    网址: http://www.sanjingchem.com
    企业联系电话:0519-86644596 13852622638👤
    📞三晶新材料科技(泰州)有限公司 ⚠️参考联系方式
    联系人:程斌
    电话:0519-86644596 13852622638
    手机:13852622638
    传真:0519-82059062
    邮箱:sales@sanjingchem.com
    通信地址: 江苏省靖江市生祠镇红北路90号
    邮编:
    🆔 联系时候可告知是从"百琢研"平台获取的信息.
    ⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

    地址:江苏省靖江市生祠镇红北路90号
    ⚠️ 未注册 · 未认证企业
    注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别
    ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
    山东丰源化工有限公司
    ⚠️ 未注册 · 未认证企业
    ⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
    数据来源于公开网络搜索,平台未作核实,请自行辨别。
    🏢敬请 企业认领
    🏬开设公司展台
    📢获取免费会员权益
    🎖️点亮专属注册企业标签
    📇展现公司完整信息 样本查看立即注册认领 →
    网址: http://www.sdfypharm.com
    企业联系电话:13310669559👤
    📞山东丰源化工有限公司 ⚠️参考联系方式
    联系人:崔总
    电话:13310669559
    手机:13310669559
    传真:0532-80922987
    邮箱:13310669559@163.com
    通信地址: 青岛市城阳区三里庄环保产业园
    邮编: 460000
    🆔 联系时候可告知是从"百琢研"平台获取的信息.
    ⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

    地址:青岛市城阳区三里庄环保产业园
    ⚠️ 未注册 · 未认证企业
    注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别
    ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
    浙江扬帆新材料股份有限公司
    ⚠️ 未注册 · 未认证企业
    ⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
    数据来源于公开网络搜索,平台未作核实,请自行辨别。
    🏢敬请 企业认领
    🏬开设公司展台
    📢获取免费会员权益
    🎖️点亮专属注册企业标签
    📇展现公司完整信息 样本查看立即注册认领 →
    网址: http://www.shoufu.cn
    企业联系电话:0571-88902507;0571-88902517;0571-88902509👤
    📞浙江扬帆新材料股份有限公司 ⚠️参考联系方式
    联系人:唐小姐
    电话:0571-88902507;0571-88902517;0571-88902509

    传真:0571-88902500
    邮箱:shoufu@shoufuchem.com
    通信地址: 浙江省杭州市滨江区信诚路31号扬帆创业大厦
    邮编: 310051
    🆔 联系时候可告知是从"百琢研"平台获取的信息.
    ⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

    地址:浙江省杭州市滨江区信诚路31号扬帆创业大厦
    ⚠️ 未注册 · 未认证企业
    注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别
    ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
    武汉至精诚医药技术有限公司
    ⚠️ 未注册 · 未认证企业
    ⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
    数据来源于公开网络搜索,平台未作核实,请自行辨别。
    🏢敬请 企业认领
    🏬开设公司展台
    📢获取免费会员权益
    🎖️点亮专属注册企业标签
    📇展现公司完整信息 样本查看立即注册认领 →
    网址: http://www.zjcchem.com
    企业联系电话:13986215120;13871097899;15927177755👤
    📞武汉至精诚医药技术有限公司 ⚠️参考联系方式
    联系人:卫先生
    电话:13986215120;13871097899;15927177755
    手机:13986215120

    邮箱:chemistry888@126.com
    通信地址: 湖北省武汉市江夏区郑店街创慧路2号东湖高新国际健康城2期14栋
    邮编: 430000
    🆔 联系时候可告知是从"百琢研"平台获取的信息.
    ⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

    地址:湖北省武汉市江夏区郑店街创慧路2号东湖高新国际健康城2期14栋
    ⚠️ 未注册 · 未认证企业
    注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别
    ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
    第 1 / 1 页

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Synthesis Of 4-Substituted Chlorophthalazines, Dihydrobenzoazepinediones, 2-Pyrazolylbenzoic Acid, And 2-Pyrazolylbenzohydrazide Via 3-Substituted 3-Hydroxyisoindolin-1-Ones
    作者:Hanh Nho Nguyen,Victor J. Cee,Holly L. Deak,Bingfan Du,Kathleen Panter Faber,Hakan Gunaydin,Brian L. Hodous,Steven L. Hollis,Paul H. Krolikowski,Philip R. Olivieri,Vinod F. Patel,Karina Romero,Laurie B. Schenkel,Stephanie D. Geuns-Meyer |发布日期:2012.4.20
    摘要:Hydrazine, Followed By Chlorination With Pocl3. We Have Also Discovered Two Novel Transformations Of 3-Vinyl- And 3-Alkynyl-3-Hydroxyisoindolinones. Addition Of Vinyl Organometallic Reagents To N,N-Dimethylaminophthalimide (8A) Provided Dihydrobenzoazepinediones 15A-15C Via The Proposed Ring Expansion Of 3-Vinyl-3-Hydroxyisoindolinone Intermediates. 3-Alkynyl-3-Hydroxyisoindolinones React With Hydrazine And

    合成参考文献


    摘要:Lubell, W. D.; St-Cyr, D. J.; Dufour-Gallant, J.; Hopewell, R.; Boutard, N.; Kassem, T.; Dörr, A.; Zelli, R., Science of Synthesis Knowledge Updates, (2013) 1, 315.
    摘要:Jie, X.; Su, W., Science of Synthesis, (2022) , 44.
    摘要:Le Bras, J.; Muzart, J., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 3, 170.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知