CAS: 618-84-8; 3-Amino-5-Nitrobenzoic Acid

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CAS号99-34-3 3,5-二硝基苯甲酸 | CAS号91088-41-4 Benzoic acid, 3... | CAS号10394-67-9 ethyl 3-amino-5... | CAS号618-85-9 3,5-二硝基甲苯 | CAS号6393-42-6 2,6-二硝基-4-甲基苯胺 | CAS号65-85-0 苯甲酸 | CAS号64-17-5 乙醇 | CAS号7803-57-8 水合肼 | CAS号110-83-8 环己烯 | CAS号55076-32-9 3-羟基-5-硝基苯甲酸甲酯 | CAS号34662-36-7 3-氯-5-硝基苯甲酸 | CAS号19714-81-9 3-amino-5-[(2-h... | CAS号23218-93-1 3-氨基-5-硝基苯甲酸甲酯 | CAS号78238-14-9 3-羟基-5-硝基苯甲酸 | CAS号5464-58-4 3-乙酰氨基-5-硝基苯甲酸 | CAS号6313-17-3 3-碘-5-硝基苯甲酸 | CAS号6307-83-1 3-硝基-5-溴苯甲酸 | CAS号76045-71-1 3-氨基-5-羟基苯甲酸 | CAS号102153-73-1 3-氨基-5-碘苯甲酸

📜3,5-二硝基苯甲酸置于sodium Hydroxide,盐酸多巴胺体系中,化学反应 1.0H,以21%的收率获得产物3-氨基-5-硝基苯甲酸
参考文献:多巴胺与3,5-二硝基苯甲酸的放热反应
标题:多巴胺与3,5-二硝基苯甲酸的放热反应
摘要:研究了由多巴胺(da)和3,5-二硝基苯甲酸(dnba)的共结晶制得的1:1结晶分子复合物daċdnba的热解.该共晶体在熔点剧烈分解,导致形成黑色固体以及少量的3-氨基-5-硝基苯甲酸(1).热解反应后进行差示扫描量热法(dsc),在分解温度下观测到一个大的放热峰.鉴于共晶daċdnba和其他化合物的dsc图谱,似乎除了强电子受体(如dnba)外,儿茶酚部分和da的氨基是出现放热峰所必需的.基于(a)黑色固体的元素分析和(b)其他共结晶paċdnba(pa:β-苯乙胺),Baċdnba(ba:苄胺),Dmdaċdnba(dmda:O,O'-二甲基多巴胺)和dhbaċdnba(dhba:3,4-二羟基苄胺),假定黑色固体主要是通过从一分子daċdnba中消除多于一分子的水形成的.版权所有©2003 John Wiley&sons,Ltd.
DOI:10.1002/poc.669

专利信息

专利号:US-6600016-B1
优先权日:1999-08-24
标题:Multifunctionalized solid support resins for synthesis of combinatorial libraries and method for using the same
发明人：CAMPIAN EUGENE; LU BOLIANG; ZHANG JINFANG
权利人:ADVANCED SYNTECH LLC
摘要:Multifunctionalized support resin for the solid phase synthesis of combinatorial libraries is disclosed. The support resin comprises a resin backbone to which is attached a template containing at least two more attachment points which carry mutiple functionalized benzyl-type linkers. Each linker displays differing chemical stability under cleavage conditions so that products can be selectively and sequentially cleaved and separated from the reaction vessel. The linkers are independently different benzyl-type moieties, and each product synthesized on the linkers may have a different chemical structure. The support resin may further comprise an additional linker which is directly attached to the resin backbone. This linker can benzyl-type linkers or other traditional cleavable-linkers. The invention is further directed to a method for the production of mutiple combinatorial libraries in a simultaneous fashion utilizing the above described support resin. The products are selectively cleaved under conditions where only one linker site is cleaved so that the product is individually separated from the reaction vessel.

专利号:RU-2117659-C1
优先权日:1992-02-04
标题:Carbopenem derivatives, their pharmaceutically acceptable salts and hydrolyzed in vivo esters (variants), method of synthesis (variants), pharmaceutical composition showing antibacterial activity, derivatives of pyrrolidine-4-ylthiol and protected derivatives of pyrrolidine-4-ylthiol