CAS: 603310-75-4; 5-Isopropylpyridin-2-Amine

该化合物是一个有机化合物,其特征为:环,是含有一个氮原子的六人芳香环;该化合物的特征为:与环和氨基组(-NH2)的5个位置相连的异丙基(1-甲基乙基)组,该组位于2位置;氨基氨基组的存在有助于其基本性和潜在的再活动,使它成为各种化学反应的候选体,包括核分裂替代物;异丙基体组增强分子的缺水性,影响其溶性以及与生物系统的互动;该化合物可能展示生物活动,使其对医药化学和药物开发感兴趣;其结构特征表明,有可能将其他化学实体合成合成,或作为有机合成的一个构件块进行合成.与许多含氮的乙基循环一样,它也可能参与氢联结,影响其物理特性和再活性.

结构式图片

相似化合物

866620-21-5 19842-07-0 1101060-79-0

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上下游产品

CAS号848841-59-8 5-异丙烯基-吡啶-2-胺 | CAS号1135437-90-9 2-nitro-5-(prop... | CAS号603310-80-1 N-[benzyl]-2-am... | CAS号1072-97-5 2-氨基-5-溴吡啶

合成工艺路线路线简述

  • 合成目标产物 5-(1-Methylethyl)-2-Pyridinamine 主要起始原料 2-Nitro-5-(Prop-1-En-2-yl)Pyridine
  • (文献来源)合成步骤主要原料 2-Nitro-5-(Prop-1-En-2-yl)Pyridine
📜3-溴-4-甲氧基吡啶置于四(三苯基膦)钯,Palladium 10% On Activated Carbon,氢气,Potassium Carbonate体系中,用 1,4-二氧六环,甲醇,水 作为反应溶剂,20.0~100.0 °C,400.01 Kpa 条件下,反应 36.0H,反应生成 5-异丙基吡啶-2-胺
参考文献:Ep3712144
标题:Ep3712144

海关参考信息

专利信息


专利号:US-9982005-B2
优先权日:2013-04-04
标 题 :Macrolides and methods of their preparation and use
发明人:MYERS ANDREW G; SEIPLE IAN BASS; ZHANG ZIYANG
权利人:HARVARD COLLEGE
摘要:Provided herein are methods of preparing macrolides by the coupling of an eastern and western half, followed by macrocyclization, to provide macrolides, including both known and novel macrolides. Intermediates in the synthesis of macrolides including the eastern and western halves are also provided. Pharmaceutical compositions and methods of treating infectious diseases and inflammatory conditions using the inventive macrolides are also provided. A general diastereoselective aldol methodology used in the synthesis of the western half is further provided.

专利号:US-8372971-B2
优先权日:2004-08-25
标 题:Heterocyclic compounds and methods of use
发明人:WRASIDLO WOLFGANG; DNEPROVSKAIA ELENA
权利人:TARGEGEN INC; WRASIDLO WOLFGANG; DNEPROVSKAIA ELENA
摘要:Heterocyclic compounds derived from benzotriazine, triazines, triazoles and oxadiazoles are disclosed. The methods of synthesis and of use of such heterocyclic compounds are also provided.

专利号:WO-2010010150-A1
优先权日:2008-07-25
标题:Synthesis of inhibitors of 11beta-hydroxysteroid dehydrogenase type 1

专利号:US-9856241-B2
优先权日:2013-07-03
标 题:Substituted benzofuranyl and benzoxazolyl compounds and uses thereof
发明人:BALOGLU ERKAN; SHACHAM SHARON; SENAPEDIS WILLIAM; MCCAULEY DILARA; LANDESMAN YOSEF; GOLAN GALI; KALID ORI; SHECHTER SHARON
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to substituted benzofuranyl and substituted benzoxazolyl compounds, and more particularly to a compound represented by Structural Formula (A): or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of Structural Formula (A), or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders.

专利号:CN-111170991-B
优先权日:2014-07-11
标题 :Antiproliferative compounds and methods of synthesis thereof

专利号:CN-111170991-A
优先权日:2014-07-11
标 题:Antiproliferative compounds and methods of synthesis thereof

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