CAS: 27773-39-3; Methyl (3Ar,3A1S,10Br)-3A-Ethyl-8-Methoxy-3A,3A1,4,6,11,12-Hexahydro-1H-Indolizino[8,1-Cd]Carbazole-5-Carboxylate

该化合物是属于类藻类的化学化合物,具体来自植物的Aspidospermagenus.该化合物具有一个复杂的结构,其特点是一个具有tetradehyma结构的复杂结构,表明碳骨骼中存在多种双联体.甲氧基和碳白酸合金合金有助于其反应性和潜在的生物活动.像这种类的藻类经常因其药理特性而研究,包括对中枢...

结构式图片

物理性质

MSDS等安全信息

    上下游产品

    11-羟基他波宁 11-Hydroxytabersonine 22149-28-6
    它勃宁 Tabersonine 4429-63-4
    (-)-11-Mesyloxytabersonine 287980-14-7
    (5R,7S,12R,19S)-2,3-Didehydro-7-Hydroxy-16-[(Methanesulfonyl)Oxy]Aspidospermidine-3-Carboxylic Acid Methyl Ester 287980-13-6
    1-[tert-Butoxycarbonyl]-3-[2-[[(2,4-Dinitrophenyl)Sulfonyl][[(2S)-4-Ethyl-2,3-Dihydro-2-Furanyl]Methyl]Amino]Ethyl]-α-Methylene-6-[(Methanesulfonyl)Oxy]-1H-Indole-2-Acetic Acid Methyl Ester 287980-11-4
    3-(2-Hydroxyethyl)-6-Methanesulfonyloxy-2-(1-Methoxycarbonylvinyl)Indole-1-Carboxylic Acid Tert-Butyl Ester 287980-10-3

    合成工艺路线路线简述

      📜1-(4-甲氧基-2-硝基苯基)丙烷-2-酮置于镍 4-甲基苯基亚硫酰氯,Sodium Chlorite,Sodium Tetrahydroborate,Sodium Dihydrogenphosphate,3 A Molecular Sieve,氨基磺酸,氢气,Sodium Methylate,Sodium Hydride,Sodium Carbonate,2,4-双(4-苯氧苯基)-1,3-二硫杂-2,4-二磷杂环丁烷-2,4-二硫化物,N,N-二异丙基乙胺,间氯过氧苯甲酸,三氯氧磷,碘甲烷体系中,用 四氢呋喃,甲醇,二氯甲烷,水,乙酸乙酯,甲苯 用作溶剂,化学反应 125.37H,反应生成Ervamycine; 11-甲氧基水甘草碱
      参考文献:Methods For Indole Alkaloid Synthesis. A Study Of The Compatibility Of The Indole-2,3-Quinodimethane Strategy For The Synthesis Of 16-Methoxy-Substituted Aspidosperma-Type Alkaloids. Synthesis Of (+)-And (-)-16-Methoxytabersonine
      标题:Methods For Indole Alkaloid Synthesis. A Study Of The Compatibility Of The Indole-2,3-Quinodimethane Strategy For The Synthesis Of 16-Methoxy-Substituted Aspidosperma-Type Alkaloids. Synthesis Of (+)-And (-)-16-Methoxytabersonine
      摘要:
      Doi:10.1021/ja00215A039

      海关参考信息

      其他信息查阅

      供应商参考报价(招募中)

      品牌试剂参考报价(招募中)

      实用工具

      ⚠️全国化工行业净网倡议书
      📋制造商识别码
      📖 海关编码查询
      📝MSDS生成器

      📌 第三方产品分析报告

      ✅ COA系统入驻 | 共享模式

      主要参考文献

      参考标题:Synthesis Of (−)-Melodinine K: A Case Study Of Efficiency In Natural Product Synthesis
      作者:Manish Walia,Christiana N. Teijaro,Alex Gardner,Thi Tran,Jinfeng Kang,Senzhi Zhao,Sarah E. O'Connor,Vincent Courdavault,Rodrigo B. Andrade |发布日期:2020.8.28
      摘要:Modern Natural Product Synthesis. Practical Criteria Include Time, Cost, And Effort Expended To Synthesize The Target, Which Tracks With Step-Count And Scale. The Execution Of A Natural Product Synthesis, That Is, The Sum And Identity Of Each Reaction Employed Therein, Falls Along A Continuum Of Chemical (Abiotic) Synthesis On One Extreme, Followed By The Hybrid Chemoenzymatic Approach, And Ultimately Biological

      合成参考文献


      参考文献:10.3987/r-1984-01-0085
      摘要:Atta-ur-Rahman _, Ali I, Bashir M. Gomaline — A New Indolenine Alkaloid from Catharanthus roseus. HETEROCYCLES. 1984;22(1):85. doi: 10.3987/r-1984-01-0085.
      参考文献:10.1016/s0031-9422(00)89527-8
      摘要:Ya-Li H, Wei-Ming C, Xiao-Zhang F. The alkaloids of Melodinus morsei. Phytochemistry. 1994 Nov;37(4):1055–7. doi: 10.1016/s0031-9422(00)89527-8.
      参考文献:10.1055/s-0037-1612061
      摘要:Lim H, Seong S, Han S. Syntheses of Post-Iboga Alkaloids. Synthesis. 2019 Feb 19;51(14):2737–58. doi: 10.1055/s-0037-1612061.
      📝 需求与反馈
      尽可能描述清楚需求与问题信息
      ×

      通知