CAS: 27750-13-6; (2S,3S)-3-Hydroxy-5-Oxotetrahydrofuran-2,3-Dicarboxylic Acid

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CAS号469-72-7 (2S,3R)-3-hydro...

专利信息

专利号:US-3764692-A
优先权日:1970-09-30
标 题 :Method of treating obesity
发明人：LOWENSTEIN J
权利人:HOFFMANN LA ROCHE
摘要:The inhibition of fatty acid synthesis is obtained in biological systems by utilizing a specific stereoisomer of hydroxycitric acid and derivatives thereof such as esters or lactones and the non-toxic salts of these compounds. It is believed that the present method involves the inhibition of citrate cleavage enzyme. Inhibition of fatty acid synthesis by the present method is useful in the treatment of obesity.

专利号:US-3993668-A
优先权日:1973-07-05
标 题:Hydroxycitric acid derivatives
发明人：GUTHRIE ROBERT WILLIAM; KIERSTEAD RICHARD WIGHTMAN
权利人:HOFFMANN LA ROCHE
摘要:Ester and amide derivatives of three-hydroxycitric acid gamma -lactone inhibit fatty acid synthesis in biological systems and are useful in the treatment of obesity and in correcting conditions of lipid abnormalities.

专利号:US-3994927-A
优先权日:1973-07-05
标题:Hydroxycitric acid derivatives
发明人：GUTHRIE ROBERT WILLIAM; KIERSTEAD RICHARD WIGHTMAN
权利人:HOFFMANN LA ROCHE
摘要:Ester and amide derivatives of three-hydroxycitric acid γ-lactone inhibit fatty acid synthesis in biological systems and are useful in the treatment of obesity and in correcting conditions of lipid abnormalities.

专利号:US-4005086-A
优先权日:1973-07-05
标 题:Hydroxycitric acid derivatives
发明人：GUTHRIE ROBERT WILLIAM; KIERSTEAD RICHARD WIGHTMAN
权利人:HOFFMANN LA ROCHE
摘要:Ester and amide derivatives of threo-hydroxycitric acid γ-lactone inhibit fatty acid synthesis in biological systems and are useful in the treatment of obesity and in correcting conditions of lipid abnormalities.

专利号:US-4006166-A
优先权日:1973-07-05
标 题:Hydroxycitric acid derivatives
发明人：GUTHRIE ROBERT WILLIAM; KIERSTEAD RICHARD WIGHTMAN
权利人:HOFFMANN LA ROCHE
摘要:Ester and amide derivatives of threo-hydroxycitric acid γ-lactone inhibit fatty acid synthesis in biological systems and are useful in the treatment of obesity and in correcting conditions of lipid abnormalities.

专利号:US-3767678-A
优先权日:1971-12-02
标 题:Hydroxycitric acid derivatives
发明人：GUTHRIE R; WIGHTMAN KIERSTEAD R
权利人:HOFFMANN LA ROCHE
摘要:ESTER AND AMIDE DERIVATIVES OF THREO-HYDROXYCITRIC ACID Y-LACTONE INHIBIT FATTY ACID SYNTHESIS IN BIOLOGICAL SYSTEMS AND ARE USEFUL IN THE TREATMETN OF OBESITY AND IN CORRECTING CONDITIONS OF LIPID ABNOMALITIES.