CAS: 20493-60-1; 5-Bromo-3-Methylisothiazole

📜5-氨基-3-甲基-异噻唑盐酸盐置于ammonium Hydroxide,氢溴酸,Copper(I) Bromide,Sodium Nitrite体系中,用 3-甲基异噻唑-5-胺,水,正戊烷 用作溶剂,化学反应生成5-溴-3-甲基异噻唑
参考文献:Thiazole Derivatives Of 2-Methoxyimino-2-(Pyridinyloxymethyl)-Phenyl-Acetamides Useful As Fungicides
标题:Thiazole Derivatives Of 2-Methoxyimino-2-(Pyridinyloxymethyl)-Phenyl-Acetamides Useful As Fungicides
摘要:本发明提供了具有在吡啶环上的异噻唑基的2-甲氧基亚氨基-2(吡啶氧甲基)苯乙酰胺,其化学式为(i),以及它们作为杀真菌化合物的用途.

专利信息

专利号:US-5523434-A
优先权日:1995-03-15
标 题 :Synthesis of bleach activators
发明人：BURNS MICHAEL E; SIMPSON ANTHONY J
权利人:PROCTER & GAMBLE
摘要:The synthesis of phenol sulfonate esters of alkanoyl amino acids is conducted in the presence of aqueous base to provide bleach activator compounds. Thus, the acid chloride of N-nonanoyl-6-aminocaproic acid is reacted with the sodium salt of p-phenol sulfonate in the presence of water at a pH in the range of about 9 to about 12 to yield the corresponding phenol sulfonate ester. The synthesis of the phenol sulfonate ester of the monononyl amide of adipic acid is also illustrated.

专利号:US-2024309142-A1
优先权日:2023-03-17
标题 :Capped block copolymers, their synthesis, manufacture, and methods of use
发明人：MAN VICTOR FUK-PONG; LI XIAOJIN HARRY; CHEN YIQING; PU GANG; HUNT JR CLINTON
权利人:ECOLAB USA INC
摘要:This disclosure relates to capped block copolymers, preferably reverse block copolymers capped with a hydrophobic group. Preferred hydrophobic groups include benzyl groups and silyl groups. In a preferred embodiment, the reverse block copolymer has at least two arms, wherein each arm is capped with a hydrophobic group. The disclosure also provides for the synthesis of the capped block copolymers as well as methods of using the capped block copolymers for defoaming and antifoaming applications.

专利号:US-10053415-B2
优先权日:2016-01-20
标题:Synthesis of a substituted indene derivative
发明人：HARWIG CURTIS; SEENISAMY JEYAPRAKASHNARAYANAN; KEREGADDE MAHESH NARAYAN; CHETIA LAKSHINDRA
权利人:AQUINOX PHARMACEUTICALS CANADA INC
摘要:This invention is directed to methods of preparing AQX-1125 having the formula: n n n n n n n n n n This invention is also directed to intermediates utilized in the methods of preparing AQX-1125.

专利号:US-12150934-B2
优先权日:2016-11-30
标 题 :Methods of using substituted pyrazole and pyrazole compounds and for treatment of hyperproliferative diseases
发明人：SIDDIQUI ARSHAD M; CIBLAT STEPHANE; CONSTANTINEAU-FORGET LEA; GRAND-MAITRE CHANTAL; GUO XIANGYU; SRIVASTAVA SANJAY; SHIPPS GERALD W; COOPER ALAN B; OZA VIBHA; KOSTURA MATTHEW W; LUTHER MICHAEL; LEVINE JEDD
权利人:BANTAM PHARMACEUTICAL LLC
摘要:Disclosed are methods of treating hyperproliferative disorders such as cancer, methods of arresting the cell cycle in cancer cells, methods of inhibiting glutathione synthesis in cancer cells, and associated compounds for use and uses in medicaments. In certain embodiments, the methods, uses and compounds are provided with reference to compounds of the structural formula (I), in which X1, X2, Z1, Z2, the ring system denoted by “aâ€?, R1, L1, L2, Q, L3, R3, L4, R4, L5, and R5 are as described herein. In certain embodiments, compounds disclosed herein are especially active against cancers having a mutant KRAS gene.

专利号:US-4790952-A
优先权日:1986-08-14
标题 :Alkyl monoperoxysuccinic acid precursors and method of synthesis
发明人：STEICHEN DALE S; KU HAO; LEWIS SHELDON N
权利人:CLOROX CO
摘要:A number of novel peracid precursors each have the general structure: ##STR1## wherein: Z is a leaving group, the conjugate acid of the leaving group being in the range of from about 4 to 15; R is a substituted or unsubstituted alkyl or alkenyl group having from about 1 to 18 carbon atoms; and M is hydrogen or an alkali or alkaline earth metal. A method is also disclosed for synthesizing a product as represented above wherein succinic anhydride, including an R constituent as defined above is dissolved in a water-miscible, non-nucleophilic solvent and an acid including a Z constituent as defined above is neutralized and deprotonated to form a nucleophile, the substituted anhydride and the nucleophile being combined to form the product. The product is a component in a dry bleach product, optionally including other adjuncts.

专利号:SK-109297-A3
优先权日:1995-03-15
标 题 :Synthesis of bleach activators