CAS: 17833-43-1; 4-Methyl-7-(((2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)-2H-Chromen-2-One

上下游产品

CAS号492-62-6 α-D-葡萄糖 | CAS号90-33-5 4-甲基伞形酮 | CAS号50-99-7 D(+)-无水葡萄糖

羟甲香豆素置于甲醇,Sodium Methylate体系中,用 甲醇,水,乙腈 用作溶剂,化学反应 76.0H,反应生成7-(α-D-吡喃葡糖氧基)-4-甲基-2H-1-苯并吡喃-2-酮
参考文献:磺基喹诺酮糖和磺基喹喔基二酰基甘油酯的简明合成,以及磺基喹喔啉酶的荧光底物的开发.
标题:磺基喹诺酮糖和磺基喹喔基二酰基甘油酯的简明合成,以及磺基喹喔啉酶的荧光底物的开发.
摘要:据估计,硫脂基磺基喹喔基二酰基甘油(sqdg)及其首基磺基糖磺基基诺糖(sq)占据了生物圈中所有有机硫的一半.Sq通过磺基喹喔啉酶(sqases)的作用从sqdg和相关的糖苷中释放出来.我们报告了sqdg的10个步骤的合成,我们将其用于制备饱和和不饱和脂质形式.我们还报告了sq和(13C6)sq的快速合成,以及sq的钠盐和钾盐的x射线晶体结构.最后,我们报告了荧光sqase底物,甲基伞形酮α-D-磺基喹诺酮苷的合成,并通过两个重组sqases对其裂解动力学进行了检查.这些化合物将有助于剖析磺基糖解作用在生物地球化学硫循环中的作用,并有助于理解磺基糖解作用的分子基础.
Doi:10.1039/c9Ob02540E

专利信息

专利号:WO-2014198994-A1
优先权日:2013-06-13
标题 :Method for the rapid analysis of cell activity
发明人：CEBOLLA RAMIREZ Ã?NGEL; MUÑOZ SUANO ALBA
权利人:BIOMEDAL S L
摘要:The invention relates to a method for the rapid determination of cell activities or states such as the synthesis of biomolecules, viability and cell growth on a microscopic level. The invention therefore relates to a specific methodology for detecting and measuring cells which are contained in hydrogel microspheres subjected to the experimental conditions of interest and are analysed using an image processor coupled to a microscope. The invention also relates to a kit comprising a microencapsulator producing monodisperse microspheres, an optical or fluorescence microscope, and an image analyser which allows the identification of the microspheres containing the cells as well as identifying the characteristics of interest thereof.

专利号:US-9469850-B2
优先权日:2007-01-18
标 题 :Oligosaccharides comprising an aminooxy group and conjugates thereof
发明人：ZHU YUNXIANG; CHENG SENG H; JIANG CANWEN; AVILA LUIS Z
权利人:GENZYME CORP
摘要:The invention provides methods for the synthesis of oligosaccharides comprising an aminooxy group. The invention further provides oligosaccharides comprising an aminooxy group, methods for coupling oligosaccharides comprising an aminooxy group to glycoproteins, and oligosaccharide-protein conjugates. Also provided are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-protein conjugate.