CAS: 15442-64-5; Zinc(Ii) 3,3'-(3,8,13,17-Tetramethyl-7,12-Divinylporphyrin-2,18-Diyl)Dipropionate

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CAS号553-12-8 原卟啉

专利信息

专利号:US-8889378-B2
优先权日:2006-08-01
标题 :Cytochrome C synthesis inhibitors
发明人：KRANZ ROBERT
权利人:KRANZ ROBERT; UNIV ST LOUIS
摘要:The invention provides methods for identifying a compound that inhibits cytochrome c synthesis. This invention further provides a method for the high throughput screening of compounds that inhibit cytochrome c synthesis.

专利号:US-2008312325-A1
优先权日:1989-07-28
标题 :Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
发明人：KENNEDY JAMES C; POTTIER ROY H; REID ROBERT L; SAC-MORALES ARNOLD; TOMALTY LEWIS L
权利人:UNIV KINGSTON
摘要:Methods of detecting and treating rapidly growing exogenous cells, such as Protista , or parasites, that preferentially accumulate a photoactivatable porphyrin in which 5-aminolevulinic acid or precursor thereof is administered to the patient, or contacted to the exogenous cells, in an amount sufficient to induce synthesis fluorescence and/or photosensitizing concentrations of a protoporphyrin IX in the exogenous cells, followed by exposure of the exogenous cells to light of photoactivating wavelengths.

专利号:US-5955490-A
优先权日:1989-07-28
标题 :Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
发明人：KENNEDY JAMES C; POTTIER ROY H; REID ROBERT L; SAC-MORALES ARNOLD; TOMALTY LEWIS L
权利人:UNIV KINGSTON
摘要:Methods of detecting and treating rapidly growing exogenous cells, such as Protista, or parasites, that preferentially accumulate a photoactivatable porphyrin in which 5-aminolevulinic acid or precursor thereof is administered to the patient, or contacted to the exogenous cells, in an amount sufficient to induce synthesis fluorescence and/or photosensitizing concentrations of a protoporphyrin IX in the exogenous cells, followed by exposure of the exogenous cells to light of photoactivating wavelengths.

专利号:US-6710066-B2
优先权日:1989-07-28
标 题 :Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
发明人：KENNEDY JAMES C; POTTIER ROY H
权利人:UNIV KINGSTON
摘要:Methods of detecting and treating rapidly growing exogenous cells, such as Protista, or parasites, that preferentially accumulate a photoactivatable porphyrin in which 5-aminolevulinic acid or precursor thereof is administered to the patient, or contacted to the exogenous cells, in an amount sufficient to induce synthesis fluorescence and/or photosensitizing concentrations of a protoporphyrin IX in the exogenous cells, followed by exposure of the exogenous cells to light of photoactivating wavelengths.

专利号:US-8748172-B2
优先权日:2006-04-27
标 题 :Cell modeling of heme deficiency using ferrochelatase mutations
发明人：FERREIRA GLORIA C; SHI ZHEN
权利人:FERREIRA GLORIA C; SHI ZHEN; UNIV SOUTH FLORIDA
摘要:Provided herein, is a means for development of ferrochelatase variants with improved tolerance towards N-methyl protoporphyrin. Also disclosed are cell assay systems utilizing the variants, as the variants would confer resistance to N-methyl protoporphyrin inhibition and thereby keep heme synthesis uninterrupted. The variants contain loop mutations that affect the NMPP-ferrochelatase interaction, and different degrees of NMPP tolerance are obtained with the introduction of loop mutations in wild-type ferrochelatase. Also disclosed is kinetic mechanism of inhibition of ferrochelatase by NMPP, using the disclosed variants whose mutations in the “porphyrin-interacting loopâ€? motif weakened the potency of NMPP as an inhibitor.

专利号:CN-109641914-A
优先权日:2016-06-29
标 题:Design and synthesis of porphyrin materials for high-efficiency organic photovoltaics