CAS: 124959-28-0; 2-Chloro-4-(Furan-2-yl)Pyrimidine

相似化合物

937271-52-8 954221-04-6 908141-98-0

上下游产品

CAS号3934-20-1 2,4-二氯嘧啶 | CAS号118486-94-5 2-(三丁基锡烷基)呋喃 | CAS号110-00-9 呋喃 | CAS号1722-12-9 2-氯嘧啶

📜2-Chloro-4-(Furan-2-yl)-1,4-Dihydropyrimidine置于2,3-二氯-5,6-二氰基-1,4-苯醌体系中,用 四氢呋喃,水 用作溶剂,化学反应 0.25H,反应生成2-氯-4-(2-呋喃基)嘧啶
参考文献:Strekowski,Lucjan; Harden,Donald B.; Grubb,William B.,Journal Of Heterocyclic Chemistry,1990,Vol. 27,# 5,P. 1393-1400
标题:Strekowski,Lucjan; Harden,Donald B.; Grubb,William B.,Journal Of Heterocyclic Chemistry,1990,Vol. 27,# 5,P. 1393-1400

专利信息

专利号:US-4021457-A
优先权日:1975-11-18
标 题 :Intermediates for polycyclic quinonoid antibiotics
发明人：KENDE ANDREW S; MILLS JOHN E; TSAY YUH-GENG
权利人:RESEARCH CORP
摘要:There is provided a novel method of synthesizing certain tetracyclic quinones. In particular, there is provided a novel route to the synthesis of certain analogs of (+)-7-deoxydaunomycinone which includes the provision of novel tri- and tetracyclic quinone intermediates. The products of the synthetic route provided herein may be converted into compounds of known anti-neoplastic activity.

专利号:US-4147706-A
优先权日:1975-11-18
标 题 :Intermediates for polycyclic quinonoid antibiotics
发明人：KENDE ANDREW S; MILLS JOHN E; TSAY YUH-GENG
权利人:RESEARCH CORP
摘要:There is provided a novel method of synthesizing certain tetracyclic quinones. In particular, there is provided a novel route to the synthesis of (+)-7-deoxydaunomycinone and analogs thereof, which includes the provision of novel tri- and tetracyclic quinone intermediates. The -7-deoxydaunomycinone derived from naturally occurring daunomycin is a known compound, which is itself an intermediate in the preparation of the clinically accepted anti-tumor antibiotics daunomycine and its derivative adriamycin.