CAS: 651358-83-7; 2-Bromo-6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Pyridine

主要参考文献

参考标题:Methods For Forming Saturated (Hetero)Cyclic Borylated Hydrocarbons And Related Compounds
摘要:The Disclosure Relates To Methods For Forming At Least Partially Saturated Cyclic And Heterocyclic Borylated Hydrocarbons, As Well As Related Compounds, Which Can Be Precursor Compounds In The Synthesis Of Any Of A Variety Of Pharmaceutical Or Medicinal Compounds With A Desired Structure And/or Stereochemistry For Drug Synthesis Or Drug Candidate Evaluation. The Methods Generally Include Reduction Of An Unsaturated Cyclic Or Heterocyclic Borylated Hydrocarbon Having A Boron-Containing Substituent At An Sp 2 -Carbon, Where Such Reduction Converts The Sp 2 -Carbon To An Sp 3 -Carbon At The Point Of Attachment Of The Boron-Containing Substituent. The Methods Can Exhibit A Selectivity For Syn-Addition During Reduction, Which Can Provide Stereospecific Products, Such As When The Unsaturated Cyclic Or Heterocyclic Reactant Is Multiply Substituted With Boron Groups And/or Other Functional Groups.

合成参考文献

参考文献:10.1055/s-0034-1378672
摘要:Knochel P, Dagousset G, François C, Leόn T, Blanc R, Sansiaume-Dagousset E. Preparation of Functionalized Lithium, Magnesium, Aluminum, Zinc, Manganese, and Indium Organometallics from Functionalized Organic Halides. Synthesis. 2014 Oct 30;46(23):3133–71. doi: 10.1055/s-0034-1378672.