CAS: 529-21-5; 3-Ethyl-4-Methylpyridine

相似化合物

20815-29-6 56675-10-6 1314908-61-6

上下游产品

brucine 5-ethyl-1,4-dimethyl-1,2,3,6-tetrahydro-pyridine 1-(4-methyl-pyridin-3-yl)-ethanone 2-chloro-3-ethyl-4-methylpyridine 3-ethyl-4-methyl-pyridin-2-ol 5-ethyl-4-methyl-pyridin-2-ol 4-methylnicotinic acid 3,4-pyridinecarboxylic acid

辛可宁置于氢氧化钾体系中,化学反应生成 3-乙基-4-甲基吡啶
参考文献:Oechsner De Coninck,Annales De Chimie (Cachan,France),1882,Vol. <5> 27,P. 454,463
标题:Oechsner De Coninck,Annales De Chimie (Cachan,France),1882,Vol. <5> 27,P. 454,463

专利信息

专利号:US-3553221-A
优先权日:1968-01-22
标 题:Certain intermediates for the production of beta-collidine
发明人：GUTZWILLER JUERG ALBERT WALTER; USKOKOVIC MILAN RADOJE
权利人:HOFFMANN LA ROCHE
摘要:THE PREPARATION OF B-COLLIDINE FROM METHYL VINYL KETONE AND AN AMINE SUCH AS, FOR EXAMPLE, BENZYLAMINE, THROUGH VARIOUS INTERMEDIATES, FOR EXAMPLE, 3-ACETYL-1BENZYL - 1,2,5,6, - TETRAHYDRO - 4 METHYLPYRIDINE, 3 ACETYL - 1,2,5,6 - TETRAHYDRO - 4 - METHYLPYRIDINE, 3ACETYL - 4 - METHYLPYRIDINE, 1 - BENZYL - 3 - (1 - HYDROXYETHYL) - 1,2,5,6 - TETRAHYDRO - 4 - METHYLPYRIDINE, 3-(1HYDROXYETHYL)-4-METHYLPYRIDINE AND 1-BENZYL-3-ETHYLENE1,2,3,6-TETRAHYDRO-4-METHYLPYRIDINE, IS DESCRIBED, B-COLLIDINE, I.E., 3-ETHYL-4-METHYLPYRIDINE, IS USEFUL IN THE SYNTHESIS OF, FOR EXAMPLE, DIHYDROQUINIDINE.

专利号:US-3655835-A
优先权日:1968-05-20
标 题 :Process for the preparation of dimethyl-thiophosphite or of organothiophosphonous acid o-monomethyl ester
发明人：SCHLIEBS REINHARD
权利人:BAYER AG
摘要:REACTING TRIMETHYLPOSPHITE OR ORGANO-PHOSPHONOUS ACID O,O-DIMETHYL ESTER WITH HYDROGEN SULFIDE IN THE PRESENCE OF A WEAK ORGANIC BASE (THE PKA OF WHICH IN AQUEOUS SOLUTION IS ABOT 0.5-8) AT A TEMPERATURE OF SUBSTANTIALLY BETWEEN ABOUT 0-70*C. AND A STARTING PRESSURE OF SUBSTANTIALLY BETWEEN ABOUT 1-65 ATMOSPHERES ABSOLUTE, TO FORM IN HIGH YIELD AND PURITY THE CORRESPONDING KNOWN DIMETHYL-THIOPHOSPHITE OR ORGANO-THIOPHOSPHONOUS ACIDO-MONO METHYL ESTER, WHICH ARE KNOWN INTERMEDIATES USEABLE FOR THE SYNTHESIS OF KNOWN BIOCIDAL, ESPECIALLY INSECTICIDAL, PHOSPHORIC ACID ESTERS.

专利号:US-2025289827-A1
优先权日:2022-12-02
标 题:Morphic forms of a mutant braf degrader and methods of manufacture thereof
发明人：YU ROBERT T; HE MINSHENG; SCHNADERBECK MATTHEW J; KREGER BRIDGET; POLLOCK ROY MACFARLANE; JIANG SIYI; LI MEIQI; CHEN BOLU; LU JIANNAN
权利人:C4 THERAPEUTICS INC
摘要:Advantageous isolated morphic forms of (3R)-3-[6-[2-cyano-3-[[ethyl(methyl)sulfamoyl]amino]-6-fluorophenoxy]-4-oxoquinazolin-3-yl]-8-[2-[1-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-4-hydroxypiperidin-4-yl]acetyl]-1-oxa-8-azaspiro[4.5]decane (Compound 1), which is a mutant BRAF degrader, and methods to prepare Compound 1 morphic forms for therapeutic applications are provided in the invention. The invention also provides improved methods for the synthesis of Compound 1, new pharmaceutical compositions comprising Compound 1, and new uses of Compound 1.

专利号:US-6432294-B1
优先权日:2000-12-14
标题 :Electrochemical activation of organic disulfides for electrophilic substitution
发明人：GLASS RICHARD S; JOUIKOV VIATCHESLAV V; BOJKOVA NINA V
权利人:UNIV ARIZONA
摘要:Electrochemical oxidation of organic disulfides is conducted in an electrolytic solution containing an arene (e.g., anthracene, acenaphthylene, phenanthrene), and depending on the arene used and/or the product desired, an organic base (e.g., pyridine) to effect the synthesis of organothiated products in good yields.

专利号:US-3663554-A
优先权日:1970-03-27
标题:Preparation of beta-collidine
发明人：GUTZWILLER JUERG ALBERT WALTER; USKOKOVIC MILAN RADOJE
权利人:HOFFMANN LA ROCHE
摘要:THE PREPARATION OF B-COLLIDINE FROM METHYL VINYL KETONE AND AN AMINE SUCH AS, FOR EXAMPLE, BENZYLAMINE, THROUGH VARIOUS INTERMEDIATES, FOR EXAMPLE, 3-ACETYL-1BENZYL - 1,2,5,6 - TETRAHYDRO-4-METHYLPYRIDINE, 3-ACETYL1,2,5,6 - TETRAHYDRO - 4 - METHYLPYRIDINE, 3 - ACETYL-4METHYLPYRIDINE, 1 - BENZYL - 3 - (1-HYDROXYETHYL)-1,2,5,6TETRAHYDRO- 4 - METHYLPYRIDINE, 3-(1-HYDROXYETHYL)-4METHYLPYRIDINE AND 1-BENZYL-3-ETHYLENE-1,2,3,6-TETRAHYDRO - 4-METHYLPYRIDINE, IS DESCRIBED. B-COLLIDINE, I.E., 3ETHYL-4-METHYLPYRIDINE, IS USEFUL IN THE SYNTHESIS OF, FOR EXAMPLE, DIHYDROQUINIDINE.

专利号:US-6617444-B1
优先权日:1999-06-30
标题 :Dinucleotide tetraphosphate crystals
发明人：MORI KENYA; MIYASHITA TAKANORI; MAEDA HIDEAKI; SATO HIROSHI; NODA YUTAKA
权利人:YAMASA CORP
摘要:The present invention is directed to crystals of P1-(2'-deoxycytidine 5'-)P4-(uridine 5'-)tetraphosphate (dCP4U) or a salt thereof and to a process for producing the crystals. The present invention also provides a process for producing dCP4U involving reacting uridine 5'-monophosphate (UMP), 2'-deoxycytidine 5'-monophosphate (dCMP), diphenyl phosphorochloridate (DPC), and pyrophosphate (PPi). The crystals of dCP4U obtained through the process according to the present invention have high purity and high stability and no hygroscopicity as compared with a freeze-dried product, and thereby serve as a useful raw material for preparing a pharmaceutical. The process for producing dCP4U according to the present invention permits use of inexpensive UMP as a raw material and realizes high yield. Thus, the process is suitable for large-scale synthesis of dCP4U.