CAS: 359-13-7; 2,2-Difluoroethanol

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431-47-0 135206-84-7 1550-44-3

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CAS号433-53-4 二氟乙酸甲酯 | CAS号359-07-9 1-溴-2,2-二氟乙烷 | CAS号454-31-9 二氟乙酸乙酯 | CAS号1137875-58-1 2,2-difluoroeth... | CAS号354-24-5 氯二氟乙酰氯 | CAS号381-73-7 二氟乙酸 | CAS号1550-44-3 乙酸2,2-二氟乙酯 | CAS号2925-22-6 2,2-difluoroace... | CAS号381-72-6 二氟乙酰氯 | CAS号67-56-1 甲醇 | CAS号354-24-5 氯二氟乙酰氯 | CAS号381-73-7 二氟乙酸 | CAS号358-64-5 tris(2,2-difluo... | CAS号359-07-9 1-溴-2,2-二氟乙烷 | CAS号75-71-8 二氯二氟甲烷 | CAS号338-65-8 2-氯-1,1-二氟乙烷 | CAS号79-14-1 羟基乙酸 | CAS号74427-22-8 2,2-二氟乙基三氟甲磺酸酯 | CAS号7556-84-5 2,2-difluoroeth... | CAS号853005-07-9 2-(2,2-difluoro...

二氟乙酸置于dimethyl Sulfide Borane体系中,用 乙醚 用作溶剂,化学反应 4.0H,以55%的收率获得2,2-二氟乙醇
参考文献:异头作用的实验研究.第四部分 由于在位置2上被乙氧基,2'-氟乙氧基,2',2,'-二氟乙氧基和2',2',2'-三氟乙氧基取代的四氢吡喃中的环反转而引起的构象平衡
标题:异头作用的实验研究.第四部分 由于在位置2上被乙氧基,2'-氟乙氧基,2',2,'-二氟乙氧基和2',2',2'-三氟乙氧基取代的四氢吡喃中的环反转而引起的构象平衡
摘要:由在145-oc记录的13 C NMR光谱确定了2-(ro)-四氢吡喃(r = Et,Ch 2 Ch 2,F,Ch 2 Chf 2 Ch 2 Cf 3)中环反转平衡的平衡常数(k).在cd 2 Cl 2和cfcl 3 / Cdcl 3中为160K (按体积计为85/15).K的其他值是在250-270K处通过异-和反-2-(ro)-4-甲基四氢吡喃的酸催化平衡而获得的(如上所述,R).Ink相对于t-1的图给出的r = Et,Ch的δh° A->e值为-0.26,-0.12,-0.05和0.13 Kcal Mol-1在cd 2 Cl 2中分别为2 Ch 2 F,Ch 2 Chf 2和ch 2 Cf 3.Cfcl 3 / Cdcl 3作用作溶剂的δh° A->e的相应值分别为-0.58,-0.15,-0.07和0.21Kcal Mol-1.导出的δs°值在cd 2 Cl 2中分别为-2.33,-2
Doi:10.1016/s0040-4020(01)89776-3

专利信息

专利号:WO-2017089470-A1
优先权日:2015-11-27
标 题:Process for the synthesis of aryldiazonium salts using nitrogen oxides in oxygen-containing gas streams, especially from industrial waste gases
发明人：HOFMANN DAGMAR; HOFMANN JOSEFA; HEINRICH MARKUS
权利人:Friedrich-Alexander-Universität Erlangen-Nürnberg
摘要:The present invention relates to a process for the synthesis of aryldiazonium salts using nitrogen oxides in oxygen-containing gas streams, especially from industrial waste gases.

专利号:US-2013338369-A1
优先权日:2011-03-07
标 题 :Process for the Synthesis of Aminobiphenylene
发明人：HEINRICH MARKUS; PRATSCH GERALD
权利人:HEINRICH MARKUS; PRATSCH GERALD; BASF SE
摘要:The present invention relates to a process for the synthesis of 2-aminobiphenylene and derivatives thereof by reacting a benzene diazonium salt with an aniline compound under basic reaction conditions.

专利号:US-10570114-B2
优先权日:2016-05-19
标题:Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling
发明人：FISK JASON S; LI XIAOYONG; Muehlfeld Mark; BAUMAN ROBERT S; OPPENHEIMER JOSSIAN; TU SIYU; NITZ MARK A; CHAKRABARTI REETAM; FEIST SHAWN D; RINGER JAMES W; LENG RONALD B
权利人:DOW AGROSCIENCES LLC
摘要:Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This includes synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.

专利号:US-2013184465-A1
优先权日:2010-09-30
标 题:Process for the synthesis of thio-triazolo-group containing compounds
发明人：DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL
权利人:DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL; BASF SE
摘要:The present invention relates to a process using specific magnesium reagents for providing thio-triazolo group-containing compounds and for the synthesis of precursors therefor. The invention furthermore relates to intermediates and to their preparation.

专利号:US-2023174490-A1
优先权日:2020-03-18
标 题 :Improved synthesis of 6-aryl-4-aminopicolinates
发明人：ZHANG CHUNMING; TU SIYU; LENG RONALD B; IRVINE NICHOLAS; SCHUITMAN ABRAHAM; SHINKLE AARON; DEVARAJ JAYACHANDRAN; ZU CHENGLI
权利人:CORTEVA AGRISCIENCE LLC
摘要:The present disclosure relates to improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates.

专利号:US-5175302-A
优先权日:1987-07-13
标 题 :Nucleophilic fluoroalkylation of aldehydes
发明人：STAHLY G PATRICK
权利人:ETHYL CORP
摘要:Aryl difluoromethyl sulfone adds to aldehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.