专利号:US-2015366976-A1 优先权日:2011-11-11 标 题:Injectable filler 发明人:NGUYEN PHI; PHAN LOC; TRAN BAO 权利人:NGUYEN PHI; PHAN LOC; TRAN BAO; MIBA MEDICAL INC 摘要:A method for producing an HA gel slurry having a plurality of cross-linked units each formed by providing an inner core using a non-biological synthesis process; and cross-linking at a first cross-link strength using a hyaluronic acid (HA) or glycosaminoglycan (GAG) made from a biological synthesis process followed by additional cross-linkings at a second cross-link strength with HA or GAG, wherein the first cross-link strength is stronger than the second cross-link strength.