2-溴-6-乙氧基吡啶置于盐酸,水体系中,化学反应生成6-氯吡啶-2-醇 参考文献:Den Hertog; De Bruyn,Recueil Des Travaux Chimiques Des Pays-Bas,1951,Vol. 70,P. 182,190 标题:Den Hertog; De Bruyn,Recueil Des Travaux Chimiques Des Pays-Bas,1951,Vol. 70,P. 182,190
专利号:US-6271379-B1 优先权日:2000-03-08 标题:Intermediates useful for the synthesis of huperzine A 发明人:TUECKMANTEL WERNER; KOZIKOWSKI ALAN P 权利人:UNIV GEORGETOWN 摘要:Intermediates useful for the synthesis of huperzine A represented by the structures below, n and methods for their synthesis, wherein: n R 1 is lower alkyl, benzyl, or substituted benzyl; n X is a suitable leaving group; n Y is an electron withdrawing group that can subsequently be converted into an amino group; n one broken line is present as a carbon—carbon bond and the other broken line is absent, where the broken line forms an unconjugated carbon—carbon double bond, which double bond may be endocyclic whereby n is 3 or the double bond may be exocyclic whereby n is 2.
专利号:US-5486615-A 优先权日:1993-11-30 标题:Method of making asymmetric DE ring intermediates for the synthesis of camptothecin analogs 发明人:COMINS DANIEL L 权利人:UNIV NORTH CAROLINA STATE 摘要:Methods of making asymmetric DE ring intermediates for the synthesis of camptothecin and camptothecin analogs employ a dioxane intermediate as the immediate precursor to the DE ring intermediate. Novel intermediates are also disclosed.
专利号:WO-2024008625-A1 优先权日:2022-07-04 标 题:Procedure for the synthesis of tirbanibulin
专利号:US-5395939-A 优先权日:1993-11-30 标题 :Method of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogs
专利号:WO-0166524-A2 优先权日:2000-03-08 标题:Intermediates useful for the synthesis of huperzine a
专利号:EP-4302831-A1 优先权日:2022-07-04 标题 :Process for synthesis of tirbanibulin
参考标题:The Synthesis Of Tethered Ligand Dimers For Pparγ-Rxr Protein Heterodimers 作者:Debra L. Mohler,Gang Shen 摘要:Heterodimeric Compounds Based On Tethering The Pparî³ Agonist Rosiglitazone To The Rxr Ligand Targretin Have Been Prepared.
合成参考文献
摘要:A.R. Katritzky, J.D. Rowe and S.K. Roy. J. Chem. Soc., B 1967, 758. 摘要:Wu, S.; Song, H.; Hu, M., Science of Synthesis: Modern Strategies in Organofluorine Chemistry , (2024) 1, 23. 参考文献:10.1007/128_2011_155 摘要:Aakeröy CB, Epa K. Controlling supramolecular assembly using electronic effects. Top Curr Chem. 2014;351():125–47. doi: 10.1007/128_2011_155.