CAS: 10512-86-4; N-Formyl-L-Alanine
该化合物是一种氨酸衍生物,其特征是附于氨基酸丙氨酸丙氨酸亚氨酸的气态基(CHO)组;一种在水和极有机溶剂中溶解的白对白的离白固体;分子结构具有与氨基组(-NH2)结合的中央碳原子(-NH2),一种碳基环(-COOH),一种氢原子和一个气基体组,使其成为生物化学应用中的一种独特化合物;N-Formylaline经常用于石化合成,并用作生产各种药物的中间体;它的再活动受到现有功能组的影响,使其能够参与各种化学反应,包括凝聚和细胞反应;此外,分子结构在生物系统中发挥作用,特别是在蛋白质合成和修改方面.由于其特定结构,N-Formylaynine也能够作为酶的子质,并可能影响到代谢途径.与许多氨基酸衍生物的衍生物一样,它具有重要的特性,在实验室中处理N-minal-se的安全性.
- 英文名称N-Formyl-L-Alanine
- 中文名称N-甲酰基-L-丙氨酸
- IUPAC名称formyl-L-alanine
- 其它别名Alanine,N-formyl-, L- (8CI); L-N-Formylalanine; N-Formyl-L-alanine; N-Formylalanine
- CAS编号10512-86-4
- MFCD编号:MFCD00037357
- EINECS号:234-045-4
- 分子式:C4H7NO3分子量:117.1
- 产品CID: 91806
- 产品分类有机原料→生命科学→氨基酸及其衍生物→丙氨酸及其衍生物
相似化合物
1142-20-7 15761-38-3 16948-16-6物理性质
MSDS等安全信息
上下游产品
formic acid L-alanin 2-(formamido)acrylic acid rac-Ala-OHN-formyl-L-alanine 4-nitrophenyl ester (S)-(+)-2-(N-methylamino)propanol (S)-N-formylalanine methyl ester N-Formyl-L-alanine benzyl ester合成工艺路线路线简述
📜Dl-丙氨酸置于乙酸酐体系中,用 甲酸,乙醚,水 用作溶剂,化学反应生成N-甲酰基-L-丙氨酸
参考文献:Neurotrophic Peptides
标题:Neurotrophic Peptides
摘要:一种新的神经营养肽被分离和纯化出来,其序列为ala-Ala-Asp-Ile-Ser-Gln-Trp-Ala-Gly-Pro-Leu.该肽能够增强胆碱能神经元中乙酰胆碱的合成,从哺乳动物海马组织的水溶性分数中获得.该肽的衍生物具有相同的生物活性,可以使用传统的固相或液相方法进行化学合成.该肽及其衍生物可用于治疗神经退行性疾病和痴呆症.
海关参考信息
- 2905121000-正丙醇
2905399099-其他二元醇
2905499000-其他多元醇
2905590090-其他无环醇的卤化、磺化等衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-8124794-B2
优先权日:2002-04-17
标题:Method for the asymmetric synthesis of beta-lactone compounds
发明人：SMITH JEFFREY W; AXELROD FUMIKO; KRIDEL STEVEN J; ROMO DANIEL; PUROHIT VIKRAM; MA GIL
权利人:SMITH JEFFREY W; AXELROD FUMIKO; KRIDEL STEVEN J; ROMO DANIEL; PUROHIT VIKRAM; MA GIL; SANFORD BURNHAM MED RES INST
摘要:The present invention features methods of treating a cancer in a subject by administering an effective amount of a beta-lactone to the subject. The invention also features methods of inhibiting angiogenesis in a subject by administering an effective amount of an inhibitor of fatty acid synthase to the subject. These methods can be used to treat a variety of cancers and other diseases and conditions. The invention also features methods of identifying beta-lactones and other compounds that can be used in the methods of the invention for the treatment of tumors, inhibition of angiogenesis, and the treatment of diseases and conditions that involve pathological angiogenesis. The invention also features methods of synthesizing beta-lactones and features novel beta-lactone compounds.
专利号:US-2006258620-A1
优先权日:2002-04-17
标 题:Novel method for the asymmetric synthesis of beta-lactone compounds
专利号:US-2010173982-A1
优先权日:2002-04-17
标题:Novel method for the asymmetric synthesis of beta-lactone compounds
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品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Enantioselective Synthesis Of Quaternary δ4 - And δ5 -Dehydroprolines Based On A Two-Step Formal [3+2] Cycloaddition Of α-Aryl And α-Alkyl Isocyano(Thio)Acetates With Vinyl Ketones作者:Amaiur Odriozola,Mikel Oiarbide,Claudio Palomo |发布日期:2017.9.18
摘要:Of Optically Active Quaternary δ4‐ And δ5‐dehydro Prolines Is Developed Based On The First Catalytic Enantioselective Conjugate Addition Of α‐substituted Isocyano(Thio)Acetates To Vinyl Ketones That Is General For Both α‐aryl And α‐alkyl Isocyano(Thio)Acetates. The New Tetrasubstituted C−n Stereocenter Is Formed Without The Need Of Any Metal Salt Due To A Bifunctional Tertiary Amine/squaramide Catalyst
合成参考文献
参考文献:10.1007/s00726-024-03424-3
摘要:Jakobsen S, Pedersen M, Nielsen CU. Structure-activity relationship of amino acid analogs to probe the binding pocket of sodium-coupled neutral amino acid transporter SNAT2. Amino Acids. 2024 Oct 19;56(1):64.
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