专利号:US-2007049637-A1 优先权日:2003-11-12 标 题:Process for the synthesis of cationic lipids 发明人:DE FERRA LORENZO; ANIBALDI MAURO; AMMIRATI ETTORE 权利人:CHEMI SPA 摘要:A process for the synthesis of lipid cations having general formula (6): n n nin which: R 1 represents a lipophilic chain; R 2 , R 3 , R 4 , which are identical or different from one another, represent C 1 -C 10 alkyl, C 1 -C 10 alkenyl, or C 1 -C 10 alkynyl radicals, optionally containing hydroxyl, ether, halogen and acyloxy functions, and X − is an oxy-anion or a halide; in which a compound of formula (2), n n nin which R 5 and R 6 , which are identical or different from one another, represent a C 1 -C 5 acyl, a benzyl group or a diol-protective group, is reacted in an alcoholic solvent with from 1 to 6 equivalents of NR 2 R 3 R 4 .
专利号:US-4806655-A 优先权日:1986-07-03 标题:Process for the stereospecific synthesis of indole derivatives 发明人:WAGNON JEAN; PLOUZANE CLAUDE; TONNERRE BERNARD; NISATO DINO 权利人:SANOFI SA 摘要:The present invention relates to a process for the stereo-specific synthesis of indole derivatives of formula: ##STR1## which consists in using 3-tosyloxy-1,2-O-isopropylidenepropane-1,2-diol (II) in an optically pure form in order to introduce the asymetric carbon C* of compound (I). Compound (II) is condensed with a suitable primary amine in order to prepare an oxazolidinone and condensation with a suitable phenol, and the oxazolidinone ring is then opened to form an indole compound (I).
专利号:WO-2024074814-A9 优先权日:2022-10-04 标题 :Composition comprising a functionalised dye and a diallylamine comonomer and use thereof 发明人:CANNON PAUL; DONLEY ADAM; LAWRENCE ANTHONY; WRIGHT GAVIN; TURNER CARL; ROBERTS PHILIP 权利人:SUBLINO LTD; COLOUR SYNTHESIS SOLUTIONS LTD 摘要:The present teachings relate to a composition comprising a functionalised dye and a diallylamine comonomer, and the use of such compositions in methods of colouring a substrate. The present teachings provide improved bonding of a dye to a substrate, and preferably allow colouring to be conducted entirely in the presence of an aqueous solvent.
专利号:WO-9005135-A2 优先权日:1988-11-02 标 题 :Process for the specific synthesis of new dithiocarbamic acid esters by substituting hydroxylated sites on mono- or polyhydroxylated molecules; products obtained by this process and their application
专利号:IE-893771-A1 优先权日:1989-11-27 标题:Process for the specific synthesis of new dithiocarbamic¹acid esters by substitution of hydroxylated sites on mono-or¹polyhydroxylated molecules, products obtained therefrom and¹their applications
专利号:WO-2005049549-A1 优先权日:2003-11-12 标题:Process for the synthesis of cationic lipids
[参考文献]: N M Carballeira, Et Al. New Advances In The Chemistry Of Methoxylated Lipids. Prog Lipid Res. 2002 Nov;41(6):437-56.
合成参考文献
参考文献:10.1515/znc-2009-11-1202 摘要:Abdel-Rahman AA, Zeid IF, Barakat HA, El-Sayed WA. Anti-hepatitis B virus activity of new substituted pyrimidine acyclic nucleoside analogues. Z Naturforsch C J Biosci. 2009 Nov;64(11-12):767–72. doi: 10.1515/znc-2009-11-1202.