CAS: 7305-59-1; (2,2-Dimethyl-1,3-Dioxolan-4-yl)Methyl 4-Methylbenzenesulfonate

该化合物是一种受保护的甘油衍生物,广泛用于有机合成,特别是在为药品和精美化学品准备手性中间体时,其主要优点包括:存在双硫基和异丙基保护群体,这加强了后续反应中的选择性.Tosyl组是一个多功能的离开组,有利于核生殖替代,而异丙基甲基在基本和温和酸性条件下提供了稳定性.这种化合物在立体选择性合成中很有价值,能够控制对氢氧化合物功能的操纵.其定义明确的再活动性和与各种反应条件的兼容性使它成为复杂的分子结构的可靠建筑块.

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23735-43-5 23788-74-1 100-79-8

欧盟法规

ECHA物质C&L通报

上下游产品

(S)-1-tosyloxy-2,3-propanediol 2,2-dimethoxy-propane acetone p-toluenesulfonyl chloride (R)-2,2-dimethyl-4-(cyanomethyl)-1,3-dioxolane (R)-(-)-4-(2-cyanophenoxy)methyl-2,2-dimethyl-1,3-dioxolane (R)-4-(2-Chloro-phenoxymethyl)-2,2-dimethyl-[1,3]dioxolane (-)-(S)-(2,3-isopropylidenedioxy)propyl benzyl sulfide

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    专利信息


    专利号:US-2007049637-A1
    优先权日:2003-11-12
    标 题:Process for the synthesis of cationic lipids
    发明人:DE FERRA LORENZO; ANIBALDI MAURO; AMMIRATI ETTORE
    权利人:CHEMI SPA
    摘要:A process for the synthesis of lipid cations having general formula (6): n n nin which: R 1 represents a lipophilic chain; R 2 , R 3 , R 4 , which are identical or different from one another, represent C 1 -C 10 alkyl, C 1 -C 10 alkenyl, or C 1 -C 10 alkynyl radicals, optionally containing hydroxyl, ether, halogen and acyloxy functions, and X − is an oxy-anion or a halide; in which a compound of formula (2), n n nin which R 5 and R 6 , which are identical or different from one another, represent a C 1 -C 5 acyl, a benzyl group or a diol-protective group, is reacted in an alcoholic solvent with from 1 to 6 equivalents of NR 2 R 3 R 4 .

    专利号:US-4806655-A
    优先权日:1986-07-03
    标题:Process for the stereospecific synthesis of indole derivatives
    发明人:WAGNON JEAN; PLOUZANE CLAUDE; TONNERRE BERNARD; NISATO DINO
    权利人:SANOFI SA
    摘要:The present invention relates to a process for the stereo-specific synthesis of indole derivatives of formula: ##STR1## which consists in using 3-tosyloxy-1,2-O-isopropylidenepropane-1,2-diol (II) in an optically pure form in order to introduce the asymetric carbon C* of compound (I). Compound (II) is condensed with a suitable primary amine in order to prepare an oxazolidinone and condensation with a suitable phenol, and the oxazolidinone ring is then opened to form an indole compound (I).

    专利号:WO-2024074814-A9
    优先权日:2022-10-04
    标题 :Composition comprising a functionalised dye and a diallylamine comonomer and use thereof
    发明人:CANNON PAUL; DONLEY ADAM; LAWRENCE ANTHONY; WRIGHT GAVIN; TURNER CARL; ROBERTS PHILIP
    权利人:SUBLINO LTD; COLOUR SYNTHESIS SOLUTIONS LTD
    摘要:The present teachings relate to a composition comprising a functionalised dye and a diallylamine comonomer, and the use of such compositions in methods of colouring a substrate. The present teachings provide improved bonding of a dye to a substrate, and preferably allow colouring to be conducted entirely in the presence of an aqueous solvent.

    专利号:WO-9005135-A2
    优先权日:1988-11-02
    标 题 :Process for the specific synthesis of new dithiocarbamic acid esters by substituting hydroxylated sites on mono- or polyhydroxylated molecules; products obtained by this process and their application

    专利号:IE-893771-A1
    优先权日:1989-11-27
    标题:Process for the specific synthesis of new dithiocarbamic¹acid esters by substitution of hydroxylated sites on mono-or¹polyhydroxylated molecules, products obtained therefrom and¹their applications

    专利号:WO-2005049549-A1
    优先权日:2003-11-12
    标题:Process for the synthesis of cationic lipids

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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: N M Carballeira, Et Al. New Advances In The Chemistry Of Methoxylated Lipids. Prog Lipid Res. 2002 Nov;41(6):437-56.

    合成参考文献


    参考文献:10.1515/znc-2009-11-1202
    摘要:Abdel-Rahman AA, Zeid IF, Barakat HA, El-Sayed WA. Anti-hepatitis B virus activity of new substituted pyrimidine acyclic nucleoside analogues. Z Naturforsch C J Biosci. 2009 Nov;64(11-12):767–72. doi: 10.1515/znc-2009-11-1202.
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