CAS: 69984-73-2; (2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-(Nonyloxy)Tetrahydro-2H-Pyran-3,4,5-Triol

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CAS号330477-04-8 n-nonyl 2,3,4,6... | CAS号2280-44-6 D-glucopyranose | CAS号143-08-8 1-壬醇 | CAS号604-69-3 β-D-葡萄糖五乙酸酯 | CAS号572-09-8 2,3,4,6-四乙酰氧基-a... | CAS号25320-96-1 1-pentanol β-D-... | CAS号58846-77-8 癸基 Β-D-吡喃葡萄糖苷 | CAS号78617-12-6 庚基-β-D-吡喃葡萄糖苷 | CAS号492-61-5 β-D-葡萄糖 | CAS号78617-12-6 庚基-β-D-吡喃葡萄糖苷 | CAS号492-61-5 β-D-葡萄糖 | CAS号143-08-8 1-壬醇

戊基beta-D-吡喃葡萄糖苷置于水体系中,用 水 作为反应溶剂,化学反应 168.0H,反应生成 壬基-β-D-葡萄吡喃糖甙
参考文献:Significantly Improved Equilibrium Yield Of Long-Chain Alkyl Glucosides Via Reverse Hydrolysis In A Water-Poor System Using Cross-Linked Almond Meal As A Cheap And Robust Biocatalyst
标题:Significantly Improved Equilibrium Yield Of Long-Chain Alkyl Glucosides Via Reverse Hydrolysis In A Water-Poor System Using Cross-Linked Almond Meal As A Cheap And Robust Biocatalyst
摘要:An Array Of Ten Beta-D-Glueopyranosides With Varied Alkyl Chain Lengths Were Enzymatically Synthesized. It Was Found That For Longer Alkyl Chains A Lower Initial Rate And Final Yield Of Glucoside Was Obtained Except For Methyl Glucoside Because Of The Severe Toxicity Of Methanol To The Enzyme. From A Thermodynamics Point Of View,The Equilibrium Constant And Gibbs Free Energy Variation Of The Glucoside Syntheses Were Systematically Investigated. To Improve The Final Yields Of The Glucosides Containing Long Alkyl Chains The Equilibrium Of The Enzymatic Glucoside Synthesis Was Altered. The Equilibrium Yield Of Decyl Beta-D-Glucoside Increased From 1.9% To 6.1% When The Water Content Was Reduced From 10% To 5% (V/v) Using Tert-Butanol As A Cosolvent And 0.10 Mol/l Of Glucose As A Substrate. As For The Other Longer Alkyl Chain Glucosides,Heptyl Beta-D-Glucoside Was Found To Have Significant Surface Activity As Well.
DOI:10.1016/s1872-2067(11)60333-1

专利信息

专利号:US-2006211083-A1
优先权日:2005-01-21
标题:Products and processes for in vitro synthesis of biomolecules
发明人：KATZEN FEDERICO; KUDLICKI WIESLAW; FLETCHER JULIA
权利人:KATZEN FEDERICO; KUDLICKI WIESLAW; FLETCHER JULIA
摘要:Provided herein are products and processes for efficiently synthesizing biomolecules in vitro using cell-free extracts derived from mammalian cells and insect cells. In an embodiment, provided is a process for preparing a cell-free extract from insect cells and mammalian cells that efficiently synthesizes post-translationally modified target proteins (e.g., glycosylated target proteins). In some embodiments, a ribonucleic acid is synthesized in vitro that comprises a cap, a 5′ untranslated region comprising an 18S rRNA binding ribonucleotide sequence, and a target ribonucleotide sequence. It has been determined that such ribonucleic acids result in efficient in vitro synthesis of a target protein using cell-free extracts derived from non-rabbit mammalian cells and insect cells.

专利号:US-2001049117-A1
优先权日:1998-08-20
标 题 :Analogs of udp-murnac peptides, assays, kits and related methods of their use
发明人：AXELROD HELENA R; BRANSTROM ARTHUR A
摘要:General compositions and methods for detecting Lipid I, Lipid II and peptidoglycan synthesis is disclosed. A method of screening for potential antibacterial agents is provided which requires bacterial membrane preparations or enriched enzyme preparations including at least one bacterial enzyme involved in the synthesis of Lipid I from UDP-MurNAc pentapeptide and undecaprenyl phosphate, at least one bacterial enzyme involved in the synthesis of Lipid II from Lipid I and UDP-GlcNAc and one or more bacterial enzymes involved in the further processing of Lipid II toward the downstream synthesis of peptidoglycan. The methods disclosed herein further provides a labeled UDP-MurNAc-peptide capable of serving as a substrate for a bacterial enzyme involved in the synthesis of Lipid I and a labeled UDP-GlcNAc capable of serving as a substrate for a bacterial enzyme involved in the synthesis of Lipid II. Conditions for further processing of Lipid II toward the downstream synthesis of peptidoglycan are also discribed.

专利号:US-11618777-B2
优先权日:2015-07-31
标 题 :Method of manufacturing membrane protein and utilization thereof
发明人：YOKOYAMA SHIGEYUKI; SHINODA TAKEHIRO; ITO KAORI; NOMURA NAOKO; KATSURA YOSHIKO; SOMEYA TOMOMI; SHIROUZU MIKAKO; HORI TETSUYA; NAKAMURA YOSHIHIRO; TANABE HIROAKI
权利人:YOKOYAMA SHIGEYUKI
摘要:In order to provide a membrane protein production method which does not require the step of solubilizing a membrane protein and which allows the membrane protein having an excellent quality to be obtained with a high yield, a method in accordance with an embodiment of the present invention includes: a step (a) of preparing a reaction solution for cell-free protein synthesis, the reaction solution containing (i) a template nucleic acid which encodes the membrane protein, (ii) a lipid, and (iii) a detergent which is contained at a concentration equal to or higher than a critical micelle concentration; and a step (b) of synthesizing the membrane protein while the concentration of the detergent in the reaction solution is maintained at a concentration equal to or higher than a critical micelle concentration.

专利号:WO-2006078821-A2
优先权日:2005-01-21
标题:Products and processes for in vitro synthesis of biomolecules

专利号:US-8916540-B2
优先权日:2008-01-15
标 题:Antibiotic compositions and related screening methods
发明人：WONG CHI-HUEY; CHENG TING-JEN; MA CHE ALEX; CHENG WEI-CHIEH
权利人:WONG CHI-HUEY; CHENG TING-JEN; MA CHE ALEX; CHENG WEI-CHIEH; ACADEMIA SINICA
摘要:Moenomycin inhibits bacterial growth by clocking the transglycosylase activity of class A penicillin-binding proteins (PBPs), which are key enzymes in bacterial cell wall synthesis. The binding affinities of moenomycin A with various truncated PBPs were compared showing that the transmembrane domain is important for moenomycin binding. Full-length class-A PBPs from 16 bacterial species were produced, and their binding activities showed a correlation with the antimicrobial activity of moenomycin against Enterococcus faecalis and Staphylococcus aureus . Moreover, a fluorescence anisotropy-based high-throughput assay was developed and used successfully for identification of transglycosylase inhibitors.