CAS: 6745-75-1; 4-Methoxy-2,5-Dimethylbenzaldehyde

上下游产品

N,N-dimethyl-formamide 2,5-Dimethyl-anisol 4-formyl-2,5-dimethylphenol dimethyl sulfate trans-cinnamic acid4-methoxy-2.5-dimethyl-trans-cinnamic acid 2,5-dimethyl-4-methoxyphenol 4-methoxy-2,5-dimethylbenzoic acid 1-methoxy-2,4,5-trimethylbenzene

2,5-二甲基苯酚置于盐酸,氢氧化钾,三氯化铝体系中,化学反应生成 2,5-二甲基对茴香醛
参考文献:A Patient With Type I Cd36 Deficiency Whose Myocardium Accumulated123I-Bmipp After 4 Years
标题:A Patient With Type I Cd36 Deficiency Whose Myocardium Accumulated123I-Bmipp After 4 Years
摘要:A 73-Year-Old Man With Aortic Regurgitation Was Examined By I-123-Alpha-Methyl-P-Iodophenylpentadecanoic Acid (Bmipp) Myocardial Single Photon Emission Computed Tomography (Spect) In 1995. Myocardial Accumulation Was Not Evident On Either The Early Or The Delayed Image Obtained 15 Minutes And 3 Hours,Respectively,After Injecting I-123-Bmipp. Flow Cytometric Analysis Of Cd36 Expression In Monocytes And Platelets Identified A Type I Cd36 Deficiency. The Patient Was Hospitalized For Severe Heart Failure In 1999. Upon Admission,The Cardiothoracic Ratio On Chest Xrays Was 73%,And The Left Ventricular End-Diastolic Diameter On Echocardiograms Was Enlarged To 77 Mm. On The Second Day,We Performed I-123-Bmipp Myocardial Spect. Myocardial Accumulation Was Evident In The Delayed,But Not In The Early Image. We Repeated I-123-Bmipp Myocardial Spect On The 10Th Day After Admission. Myocardial Accumulation Was Evident On Both Early And Delayed Images. Tc-99M-Tetrofosmin Myocardial Spect Was Immediately Performed After I-123-Bmipp Myocardial Spect To Distinguish Myocardial From Pooling Images In The Left Ventricle,But,Because The Images From Both 99Mtc-Tetrofosmin And I-123-Bmipp Myocardial Spect Were Idential,We Considered That The 123I-Bmipp Myocardial Spect Images Reflected The Actual Myocardial Condition.The Cd36 Molecule Transports Long-Chain Fatty Acid (Lcfa) On The Myocardial Membrane,But I-123-Bmipp Scintigraphy Does Not Show Any Myocardial Accumulation In Patients With Type I Cd36 Deficiency,Indicating That Myocardial Lcfa Uptake occurs Through Cd36 On The Human Myocardial Membrane. Even Though Our Patient Had Type I Cd36 Deficiency,Bmipp Was Uptaken By The Myocardium During Heart Failure,Suggesting A Variant Pathway On The Human Myocardial Membrane For Lcfa Uptake.
DOI:10.1007/bf02987845

专利信息

专利号:US-5783577-A
优先权日:1995-09-15
标题 :Synthesis of quinazolinone libraries and derivatives thereof
发明人：HOUGHTEN RICHARD A; OSTRESH JOHN M
权利人:TREGA BIOSCIENCES INC
摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.

专利号:US-5175302-A
优先权日:1987-07-13
标 题 :Nucleophilic fluoroalkylation of aldehydes
发明人：STAHLY G PATRICK
权利人:ETHYL CORP
摘要:Aryl difluoromethyl sulfone adds to aldehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.

专利号:US-4837327-A
优先权日:1987-07-13
标 题 :Process for nucleophilic fluoroalkylation of aldehydes
发明人：STAHLY G PATRICK
权利人:ETHYL CORP
摘要:Aryl difluoromethyl sulfone adds to alkehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.

专利号:US-4999429-A
优先权日:1989-01-09
标 题 :Process for the preparation of α,α,β-1-trifluoro-1-olefinic derivatives
发明人：STAHLY G PATRICK
权利人:ETHYL CORP
摘要:Aryl difluoromethyl sulfone adds to aldehydes under phase transfer conditions to give novel substituted alcohols of the general formula n n RCH(OH)CF.sub.2 SO.sub.2 Ar (I) n n wherein R is an aryl, cycloaliphatic, sec- or tert-aliphatic, or heterocyclic group and Ar is an aryl group. The substituted alcohols of formula I are of particular utility as intermediates in the synthesis of a variety of useful end products. For example, the products of formula I may be utilized in desulfonylation reactions, oxidation reactions and fluorination reactions.

专利号:WO-0053313-A2
优先权日:1999-03-09
标 题:Lanthanide catalysts for synthesis of compounds and combinatorial libraries

专利号:WO-9811438-A1
优先权日:1996-09-13
标题 :Synthesis of quinazolinone libraries and derivatives thereof