CAS: 57078-98-5; 4-(2,5-Dioxo-2,5-Dihydro-1H-Pyrrol-1-yl)Butanoic Acid

相似化合物

57078-99-6 55750-53-3 57079-01-3

上下游产品

maleic anhydride 4-amino-n-butyric acid 8H11NO5C8H11NO5 N-benzyloxycarbonyl-3-(N-maleimidobutyryloxymethyl)-2,2,4,4-tetramethylpyrrolidine 4-maleimidobutyric acid N-hydroxysuccinimide ester 4-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-butanoic acid 4-tert-butyldimethylsilanyloxymethyl-phenyl ester 4-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-butanoic acid 4-hydroxymethyl-2-nitro-phenyl ester

4-(3-Carboxypropylamino)-4-Oxobut-2-Enoic Acid 以 水 作为反应溶剂,化学反应生成 4-马来酰亚胺丁酸
参考文献:Practical Synthesis Of Maleimides And Coumarin-Linked Probes For Protein And Antibody Labelling Via Reduction Of Native Disulfides
标题:Practical Synthesis Of Maleimides And Coumarin-Linked Probes For Protein And Antibody Labelling Via Reduction Of Native Disulfides
摘要:细胞对蛋白质或抗体运动的追踪,检测和感知是增进我们对生物分子相互作用和活性理解的重要方面.用荧光染料修饰的抗体也是有价值的工具,特别是在免疫学研究中.这里我们描述了一项原理验证研究,涉及一种新的水溶性香豆素探针,该探针具有马来酰亚胺巯基反应单元,用于荧光标记生物分子.重点包括:(1)n-取代马来酰亚胺的便捷水基制备,(2)活化马来酰亚胺酯的一锅法制备,以及(3)硒醇促进的本征二硫键还原和无显著活性损失的抗体"位点特异性"标记的生物偶联方案.
DOI:10.1039/b904060A

专利信息

专利号:US-8647823-B2
优先权日:2005-07-22
标 题 :Polynucleotide synthesis on a modified surface
发明人：PARK JOON-WON; HONG BONG-JIN
权利人:PARK JOON-WON; HONG BONG-JIN; POSTECH FOUNDATION; POSCO
摘要:The present invention relates to a method for the synthesis of a polynucleotide on a modified surface of a substrate, wherein the modified surface is obtained by chemically modifying with macromolecules in which a plurality of termini of the branched region are bound to the surface and a terminus of the linear region is functionalized.

专利号:US-2010035799-A1
优先权日:2002-07-24
标 题:Method for the synthesis of anthracycline-peptide conjugates
发明人：FERNANDEZ ANNE-MARIE; DUBOIS VINCENT
权利人:UNIV CATHOLIQUE LOUVAIN; DIATOS SA
摘要:The present invention relates to a method for the preparation of a compound of formula (I) or pharmaceutically acceptable salts thereof and intermediates thereof, comprising the steps of: n n n n n n n n n n n n a) halogenating a compound of formula (II), resulting in compound of formula (IIa), n n n n n n n n n n n n n n n n b) reacting a compound of formula (IIa) at its 14 position with the thiol moiety of a peptide of formula (III), optionally in the presence of a suitable linker, to obtain said compound of formula (I), n n n n n n n n n n n n n n n n wherein R 1 represents OH, NH 2 or NH-peptide; R 2 represents H or —CO-peptide; R 3 represents OCH 3 , OH or H; R 4 represents H, or COCF 3 ; R 5 represents OH, O-tetrahydropyranyl or H; R 6 represents OH or H; R 7 represents H, OH, OCO(CH 2 ) 3 CH 3 or OCOCH(OC 2 H 5 ) 2 ; R 8 represents OH or H; R 9 represents OH or H; R 10 represents a halogen and L is an optional suitable linker arm.

专利号:US-2024215280-A1
优先权日:2022-10-31
标 题:In situ core/shell perovskite nanocrystal material, method of preparation thereof, and light emitting device comprising the same
发明人：LEE TAE-WOO; KIM JOO SUNG
权利人:SEOUL NAT UNIV R&DB FOUNDATION; PEROLED CO LTD
摘要:The present inventive concept relates to an in situ core/shell perovskite nanocrystal film formed by an in situ nanocrystal synthesis process, a method for producing the same, and a light emitting device comprising the same as a light-emitting layer. The in situ core/shell perovskite nanocrystal film formed by the in situ nanocrystal synthesis process according to the present inventive concept exhibits a strong charge confinement effect by nanocrystal formation, and can simultaneously greatly improve the luminescence efficiency and lifetime by maintaining the fast charge transport capability of polycrystalline perovskite.

专利号:WO-2025101943-A1
优先权日:2023-11-10
标 题:Nucleic acid-guided dna synthesis
发明人：STERNBERG SAMUEL HENRY; TANG STEPHEN; ZHANG DENNIS JAMES; WIEGAND TANNER; THOMAS GEORGE JERRIN; LAMPE GEORGE DAVIS; KANG SHANNON
权利人:UNIV COLUMBIA
摘要:The present disclosure provides systems, compositions, methods, and kits, for guided DNA synthesis and genome engineering. Particularly, the present disclosure provides systems, compositions, methods, and kits comprising a defense-associated reverse transcriptase (DRT), or a nucleic acid encoding thereof, and an engineered target nucleic acid comprising one or more sequence of interest, or a nucleic acid encoding thereof.

专利号:WO-2023090935-A1
优先权日:2021-11-18
标 题 :Method for producing agm peptides that bind specifically to nucleolin
发明人：KIM JAE IL; HWANG KOOK SANG; LEE JU YOUNG; KIM DONG MIN; WON SUN WOO; JO EUN JIN
权利人:ANYGEN CO LTD
摘要:According to the production method of the present invention, AGM peptides that bind specifically to nucleolin can be obtained with high purity and high yields. Accordingly, a method that enables the mass-synthesis of AGM peptides that can be usefully used for diagnosis and targeted drug delivery in cancer therapy, can be presented.

专利号:US-7928211-B2
优先权日:2006-05-03
标题:Method for preparing compounds by nucleic acid directed synthesis
发明人：HANSEN NILS JAKOB VEST; BLAKSKJAER PETER; PETERSEN LARS KOLSTER
权利人:VIPERGEN PHARMACEUTICALS APS
摘要:The present invention provides compositions, compounds and methods for in vitro DNA display technology, allowing display of a variety of molecules, in particular molecules obtained by water incompatible mechanisms. Advantages of such methods are that combinatorial libraries can be constructed comprising molecules which are obtained through water incompatible reactions.