CAS: 18908-07-1; 3-Methoxyphenyl Isocyanate

上下游产品

CAS号32315-10-9 三光气 | CAS号536-90-3 间氨基苯甲醚 | CAS号3532-20-5 1-(3-methoxyphe... | CAS号586-38-9 3-甲氧基苯甲酸 | CAS号51028-35-4 (4-nitrophenyl)... | CAS号5813-86-5 3-甲氧基苯甲酰胺 | CAS号1711-05-3 3-甲氧基苯甲酰氯 | CAS号503-38-8 氯甲酸三氯甲酯 | CAS号108716-30-9 (3-methoxy-phen... | CAS号141-43-5 2-氨基乙醇 | CAS号28170-54-9 3-(3-methoxyphe... | CAS号364073-76-7 (2S)-N2-(9-ethy... | CAS号132-32-1 3-氨基-9-乙基咔唑 | CAS号118-31-0 1-萘甲胺 | CAS号16460-28-9 1,3-bis(3-metho... | CAS号17641-08-6 2-氯-N-(3-甲氧基苯基)-乙酰胺 | CAS号16460-27-8 1,3,5-tris(3-me... | CAS号112439-56-2 N-(3-methoxyphe... | CAS号37528-40-8 4-ethyl-7-metho... | CAS号37528-45-3 7-methoxy-4-phe...

3-甲氧基苯甲酰胺置于[(N-Tosylimino)Iodo]Benzene体系中,用 二氯甲烷 用作溶剂,化学反应 0.5H,反应生成3-甲氧基苯异氰酸
参考文献:(tosylimino)苯基λ 3-Iodane作为试剂用于通过芳香族和脂肪族甲酰胺的霍夫曼重排甲基氨基甲酸酯的合成
标题:(tosylimino)苯基λ 3-Iodane作为试剂用于通过芳香族和脂肪族甲酰胺的霍夫曼重排甲基氨基甲酸酯的合成
摘要:一种新的,温和的程序使用(tosylimino)苯基-λ芳香族和脂肪族羧酰胺的霍夫曼重排3-Iodane,Phints,作为试剂被报告.由于反应条件温和,该方法对于取代的苯甲酰胺的霍夫曼重排特别有用,该苯甲酰胺通常会提供与其他高价碘氧化剂的复杂反应混合物.羧酰胺与phints反应的温和反应条件和高选择性可以分离最初形成的不稳定异氰酸酯,或通过用醇处理将其随后转化为稳定的氨基甲酸酯.
Doi:10.1021/jo300007C

专利信息

专利号:US-8017323-B2
优先权日:2003-03-26
标 题 :Free reactant use in nucleic acid-templated synthesis
发明人：LIU DAVID R; SAKURAI KAORI
权利人:HARVARD COLLEGE
摘要:The present invention provides methods and compositions for expanding the scope of chemical reactions that can be performed during nucleic acid-templated organic syntheses. In particular, nucleic acid-templated chemistries are used to produce reaction intermediates attached to an oligonucleotide that can be used to identify the reaction intermediates and/or the resulting reaction products. The reaction intermediates then are reacted with free reactants (for example, reactants that are difficult or impractical to couple to an oligonucleotide) to produce a reaction product. This approach expands the scope of reagents useful in nucleic acid-templated syntheses to reagents that do not need to be or cannot be tethered to an oligonucleotide. The reagents, however, still permit the synthesis of reaction products attached to oligonucleotides that can be used to identify the reaction products.

专利号:WO-03013740-A1
优先权日:2001-08-03
标题 :4- AND 5-AMINO-α, β UNSTATURATED ESTER SOLID SUPPORT TEMPLATES, METHOD OF PREPARATION AND FOR USING THE SAME
发明人：LOU BOLIANG; MAJJLI ADNAN M M
权利人:ADVANCED SYNTECH LLC
摘要:A substituted α, β-unsaturated ester template of the general formula (1) where: P is an insoluble substrate; n is 1 or 2; X is an atom or a functional group connecting the polymer and the linker L. having a structure such as but not limited to oxygen, ester, amide, sulfur, silicon and carbon; L is a multifunctional chemical monomer in which one functional group reacts with the polymer to form a covalent bond (X) and one other of the functional groups react with one of the R groups (R1, R2, R3, R5, or R6) through a plurality of chemical reactions to provide the desired templates for further chemistry. The ester template is useful for the solid phase synthesis of heterocycle compounds.

专利号:US-2005192265-A1
优先权日:2003-03-20
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-6906056-B2
优先权日:1998-06-22
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
权利人:LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-2022281888-A1
优先权日:2019-09-25
标题:Bicyclic carboxylates as modulators of transporters and uses thereof
发明人：SANDANAYAKA VINCENT; GORECZNY GREGORY
权利人:NIROGY THERAPEUTICS INC
摘要:The present invention generally relates to the field of transporter modulators, e.g., monocarboxylate transporter inhibitors, and more particularly to new bicyclic enone carboxylate compounds, the synthesis and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with monocarboxylate transporter activity such as in treating cancer and other neoplastic disorders, tissue and organ transplant rejection.

专利号:US-9879050-B2
优先权日:2013-08-30
标 题 :Substituted urea depsipeptide analogs as activators of the CLPP endopeptidase
发明人：LEE RICHARD E; ZHAO YING; GRIFFITH ELIZABETH; ZHENG ZHONG; SINGH AMAN P
权利人:ST JUDE CHILDREN'S RES HOSPITAL
摘要:In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.