CAS: 1568-70-3; 4-Methoxy-2-Nitrophenol

该化合物是属于硝营养蛋类的有机化合物,其特征为甲氧基组(-OCH3)和硝基组(-NO2),分别附于苯球环,具体地在4和2个位置上.该化合物一般是黄色晶状固体,以其在有机溶剂中的中等溶解性以及水中的溶解性有限而著称.甲基氧基和硝基组的存在有助于其化学再活动,使其成为有机合成和各种化学反应的有用中间体.4-甲基氧-2-niconterenol在苯球圈上可以显示出因氢氧基(-OHA)而出现的酸性,并可能参与电益替代反应.此外,该化合物在染料,制药和农业化学领域也有应用.在处理该化合物时,应当采取安全防范措施,因为硝营养蛋可以有毒并可能对环境造成危害.

结构式图片

相似化合物

20734-76-3 89-39-4 15174-02-4

欧盟法规

ECHA物质C&L通报

上下游产品

1,4-dimethoxy-2-nitrobenzene p-tert-butoxyanisole p-Isopropoxyphenyl methyl ether 4-methoxy-2-nitroacetanilide 1-butoxy-4-methoxy-2-nitro-benzene 1-ethoxy-4-methoxy-2-nitro-benzene 4-methoxy-2-nitro-1-propoxy-benzene 2-amino-4-methoxyphenol

合成工艺路线路线简述

    4-叔-丁氧基苯甲醚置于硝酸,溶剂黄146,丙酸体系中,化学反应生成4-甲氧基-2-硝基酚
    参考文献:240.芳族取代形式ro和rr'N的基团的相对指令功率.部x. 4-叔butoxyanisole和4-的硝化异propoxyanisole
    标题:240.芳族取代形式ro和rr'N的基团的相对指令功率.部x. 4-叔butoxyanisole和4-的硝化异propoxyanisole
    摘要:
    Doi:10.1039/jr9360001148

    海关参考信息

    专利信息


    专利号:US-2010324266-A1
    优先权日:2000-09-11
    标题:Photocleavable Protecting Groups
    发明人:BARONE ANTHONY D; MCGALL GLENN H
    权利人:AFFYMETRIX INC
    摘要:Novel compounds are provided, which are useful as linking groups in chemical synthesis, preferably in the solid phase synthesis of oligonucleotides and polypeptides. These compounds are generally photolabile and comprise protecting groups which can be removed by photolysis to unmask a reactive group. The protecting group has the general formula Y, wherein Y is a chemical structure as shown in FIG. 1 . Also provided is a method of forming, from component molecules, a plurality of compounds on a support, each compound occupying a separate predefined region of the support, using the protected compounds described above.

    专利号:US-2011028350-A1
    优先权日:1995-12-15
    标题:Photocleavable protecting groups
    发明人:MCGALL GLENN H; BARONE ANTHONY D
    权利人:AFFYMETRIX INC
    摘要:Novel compounds are provided, which are useful as linking groups in chemical synthesis, preferably in the solid phase synthesis of oligonucleotides and polypeptides. These compounds are generally photolabile and comprise protecting groups which can be removed by photolysis to unmask a reactive group. The protecting group has the general formula Y, wherein Y is a chemical structure as shown in FIG. 5. Also provided is a method of forming, from component molecules, a plurality of compounds on a support, each compound occupying a separate predefined region of the support, using the protected compounds described above.

    专利号:US-2009298819-A1
    优先权日:2008-05-27
    标 题 :Compositions, Synthesis, And Methods Of Using Piperazine Based Antipsychotic Agents

    专利号:US-8207163-B2
    优先权日:2008-05-27
    标题 :Compositions, synthesis, and methods of using piperazine based antipsychotic agents
    发明人:BHAT LAXMINARAYAN; MOHAPATRA PRABHU PRASAD; ADIEY KOUACOU
    权利人:BHAT LAXMINARAYAN; MOHAPATRA PRABHU PRASAD; ADIEY KOUACOU; REVIVA PHARMACEUTICALS INC
    摘要:The present invention provides novel piperazine derivatives which can be advantageously used for treating schizophrenia and related psychoses such as acute manic, bipolar disorder, autistic disorder and depression.

    专利号:SG-173842-A1
    优先权日:2009-02-26
    标 题 :Compositions, synthesis, and methods of utilizing arylpiperazine derivatives

    专利号:AU-2010217772-B2
    优先权日:2009-02-26
    标题 :Compositions, synthesis, and methods of utilizing arylpiperazine derivatives
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    主要参考文献

    参考标题:The Regiospecific Synthesis Of The A And B Rings Of Phomazarin
    作者:Vincent Guay,Paul Brassard |发布日期:1987.11
    摘要:Elaboration Of The A Ring Of Phomazarin By The Conrad-Limpach Approach Has Been Shown To Be Possible In The Case Of A Protected Hydroquinone Substrate. However Similar Condensations Using A Suitably Substituted Naphthoquinone Gave A Lactam Instead Of The Expected Benzoquinolone. Attempts To Annulate Simplified Models Of The A-B Rings With The Appropriate Diene Have Also Been Successful Albeit In Low

    合成参考文献


    摘要:Irudayanathan, F. M.; Lee, S., Science of Synthesis Knowledge Updates, (2019) 2, 33.
    摘要:Lumb, J.-P.; Esguerra, K. V. N., Science of Synthesis: Catalytic Oxidation in Organic Synthesis, (2017) 1, 623.
    摘要:M. Rapoport, C. K. Hancock and E. A. Meyers, J. Am. Chem. Soc. 83, 3489 (1961).
    摘要:J. Sunkel and H. Staude, Ber. Bunsenges. Physik. Chem. 72, 567 (1968).
    摘要:H. Staude and H. Teupel, Z. Elektrochem. 61, 181 (1957).
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