CAS: 14690-00-7; 2-(Benzyloxy)Propane-1,3-Diol

该化合物是一种有机化合物,其结构特征是丙烷基脊柱,带有苯基醚替代物,这种化合物一般是无色的,可粉黄液或固体,视其纯度和温度而定;它溶于乙醇和乙醚等有机溶剂,但由于其具有水分的苯基组,在水中溶解性有限;其结构中存在氢氧基,其作为有机合成中多种中间体的潜力,特别是在生产药品和精美化学品方面.此外,2-苯氧基-1,3-丙烷二醇可能具有各种功能性,包括潜在的抗氧化活动以及参与化学反应的能力,如乙化或酯化.安全数据表明,与许多有机化合物一样,应当谨慎处理,使用适当的个人保护设备避免皮肤和眼睛接触.

英文名称2-(Benzyloxy)Propane-1,3-Diol
中文名称2-苄氧基-1,3-丙二醇
IUPAC名称2-(benzyloxy)propane-1,3-diol
其它别名2-O-Benzylglycerol; 2-(Phenylmethoxy)-1,3-Propanediol; 2-Benzyloxy-Propane-1,3-Diol; 1,3-Propanediol, 2-(Phenylmethoxy)-; Inchi=1/c8H7Fo3/c9-6-1-3-7(4-2-6)12-5-8(10)11/h1-4H,5H2,(H,10,11; Ft
CAS编号14690-00-7
MFCD编号:MFCD00075493
分子式:C10H14O3
分子量:182.22
产品CID: 701134
产品分类有机原料 → 醇,酚,酚醇类化合物及衍生物

相似结构搜索
产品信息参考;;;
InChIKey: UDIPIOHLDFSMLR-UHFFFAOYSA-N
InChI=1S/C10H14O3/c11-6-10(7-12)13-8-9-4-2-1-3-5-9/h1-5,10-12H,6-8H2…
计算化学: 氢键受体数3.0氢键供体数2.0可旋转键数5.0

MSDS等安全信息

警示词Warning
危险描述H315-H319-H335-
防范说明P233-P260-P261-P264-P271-P280-P302+P352-P304-P304+P340-P312-P321-P332+P313-P337+P313-P340-P362-P403-P403+P233-P405-P501-
UN编号NONH for all modes of transport
安全声明S22-S24/25
WGK Germany3

上下游产品

合成工艺路线路线简述

3-二甲基氨基苯甲醛置于camphor-10-Sulfonic Acid,氯化铵体系中,用甲醇,氯仿用作溶剂,化学反应 74.5H,反应生成2-苄氧基-1,3-丙二醇
参考文献:结构简单的亚苄基型光不稳定二醇保护基.
标题:结构简单的亚苄基型光不稳定二醇保护基.
摘要:已经开发了两种结构简单的对光不稳定的用于释放1,2-和1,3-二醇的保护基.可以以高收率保护二醇,并以高化学效率将其从其相应的缩醛中释放出来.
Doi:10.1021/acs.Orglett.6B02777

海关参考信息

2902300000-甲苯
2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-5585252-A
优先权日:1988-08-30
标题 :Enantio- and regioselective synthesis of organic compounds using enol esters as irreversible transacylation reagents
发明人：WONG CHI-HUEY; WANG YI-FONG; HENNEN WILIAM J
权利人:SEARLE & CO
摘要:A process for irreversible regio- and stereoselective enzyme catalyzed acylation of alcohols using enol esters as acylating reagents is disclosed. The present invention permits the selective modification of hydroxyl group(s) of chiral and meso alcohols, including sugars, organometallics, and glycosides. The enol freed upon transesterification rapidly tautomerizes to the corresponding volatile aldehyde or ketone thereby preventing the reverse reaction from occurring.

专利号:US-5106750-A
优先权日:1988-08-30
标题:Enantio- and regioselective synthesis of organic compounds using enol esters as irreversible transacylation reagents
发明人：WONG CHI-HUEY; WANG YI-FONG; HENNEN WILLIAM J; BABIAK KEVIN A; DYGOS JOHN H; NG JOHN S
权利人:SEARLE & CO
摘要:A process for irreversible regio- and stereoselective enzyme catalyzed acylation of alcohols using enol esters as acylating reagents is disclosed. The present invention permits the selective modification of hydroxyl group(s) of chiral and meso alcohols, including sugars, organometallics, and glycosides. The enol freed upon transesterification rapidly tautomerizes to the corresponding volatile aldehyde or ketone thereby preventing the reverse reaction from occurring.

专利号:US-2005266068-A1
优先权日:2002-05-24
标题 :Cardiolipin molecules and methods of synthesis
发明人：AHMAD MOGHIS U; UKKALAM MURALI K; AHMAD IMRAN
权利人:NEOPHARM INC
摘要:The invention provides new synthetic routes for cardiolipin with different fatty acids and/or alkyl chains with varying chain length and also with or without unsaturation, particularly a short-chain cardiolipin. The methods comprise reacting a 1,2-O-sn-diacyl/1,2-O-sn-dialkyl glycerol or a 2-O-protected glycerol, with a phosphoramidite reagent or a phosphate triester to produce a protected cardiolipin, which is deprotected to prepare the short chain cardiolipin. The reaction schemes can be used to generate new variants of cardiolipin. The cardiolipin prepared by the present methods can be incorporated into liposomes, which can also include active agents such as hydrophobic or hydrophilic drugs. Such liposomes can be used to treat diseases or in diagnostic and/or analytical assays. Liposomes can also include ligands for targeting a particular cell type or specific tissue.

专利号:WO-2004039817-A9
优先权日:2002-10-16
标题 :Cardiolipin molecules and method of synthesis
发明人：AHMAD MOGHIS U; UKKALAM MURALI K; AHMAD IMRAN
权利人:NEOPHARM INC; AHMAD MOGHIS U; UKKALAM MURALI K; AHMAD IMRAN
摘要:The invention provides new synthetic routes for cardiolipin with different fatty acids and/or alkyl chains with varying chain length and also with or without unsaturation, particularly a short-chain cardiolipin. The methods comprise reacting a 1,2-O-sn-diacyl/1,2-O-sn-dialkyl glycerol or a 2-O-protected glycerol, with a phosphoramidite reagent or a phosphate triester to produce a protected cardiolipin, which is deprotected to prepare the short chain cardiolipin. The reaction schemes can be used to generate new variants of cardiolipin. The cardiolipin prepared by the present methods can be incorporated into liposomes, which can also include active agents such as hydrophobic or hydrophilic drugs. Such liposomes can be used to treat diseases or in diagnostic and/or analytical assays. Liposomes can also include ligands for targeting a particular cell type or specific tissue.

专利号:DE-68929190-T2
优先权日:1988-08-30
标题:Enantio- and regioselective synthesis of organic compounds with enol esters as irreversible transacylation reagents

专利号:JP-2843606-B2
优先权日:1988-08-30
标题 :Enantio- and regio-selective synthesis of organic compounds using enol esters as irreversible acyl transfer reagents