CAS: 142253-56-3; 1-Boc-Azetidine-3-Yl-Methanol

相似化合物

928038-44-2 95849-02-8 618446-42-7

上下游产品

CAS号142253-55-2 1-B°C-氮杂环丁烷-3-羧酸 | CAS号610791-05-4 N-B°C-氮杂环丁烷-3-甲酸甲酯 | CAS号72351-36-1 1-二苯甲基-3-羟甲基-氮杂环丁烷 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号928038-44-2 3-甲羟基氮杂环丁烷盐酸盐 | CAS号543-27-1 氯甲酸异丁酯 | CAS号541-41-3 氯甲酸乙酯 | CAS号142253-57-4 (1-(叔丁氧羰基)氮杂环丁烷... | CAS号95849-02-8 氮杂环丁烷-3-基甲醇 | CAS号253176-94-2 1-B°C-(3-碘甲基)氮杂环丁烷 | CAS号177947-96-5 3-甲酰基氮杂环丁烷-1-羧酸叔丁酯 | CAS号876589-20-7 3-(氯甲基)氮杂丁烷-1-羧酸叔丁酯 | CAS号892408-42-3 TERT-BUTYL 3-(T... | CAS号942308-05-6 1-(叔丁氧基羰基)-3-甲氧...

3-亚甲基氮杂丁烷-1-羧酸叔丁酯置于硼烷四氢呋喃络合物,双氧水,Sodium Hydroxide体系中,用 四氢呋喃 用作溶剂,化学反应 2.0H,以90.9%的收率获得3-羟甲基氮杂环丁烷-1-羧酸叔丁酯
参考文献:截短侧耳素类抗生素
标题:截短侧耳素类抗生素
摘要:本发明涉及通式(ⅰ)所示的截短侧耳素类抗生素,其药学上可接受的盐,其前体药物,其溶剂化物或其立体异构体,其中r1,R2,R2A,R2B,M,X和y的定义同说明书中所述定义;本发明还涉及这些化合物的制备方法,含有这些化合物的药物组合物和药物制剂,以及这些化合物在制备治疗和/或预防由微生物引起的疾病的药物中的应用.

专利信息

专利号:WO-2018108954-A1
优先权日:2016-12-12
标题 :Process for the preparation of 2-(3-(fluoromethyl)azetidin-1-yl)ethan-1-ol
发明人：GOSSELIN FRANCIS; LINGHU XIN
权利人:HOFFMANN LA ROCHE; GENENTECH INC
摘要:Methods of making 2-(3-(fluoromethyl)azetidin-1-yl)ethan-1-ol 9, an intermediate useful for the synthesis of estrogen receptor modulating compounds are described.

专利号:US-2009170828-A1
优先权日:2006-06-12
标题:Azetidine Derivatives as Inhibitors of Stearoyl-Coenzyme a Delta-9 Desaturase
发明人：ISABEL ELISE; OBALLA RENATA; POWELL DAVID; ROBICHAUD JOEL
权利人:ISABEL ELISE; OBALLA RENATA; POWELL DAVID; ROBICHAUD JOEL
摘要:Azetidine derivatives of structural formula I are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease; atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; liver steatosis; and non-alcoholic steatohepatitis. (I)

专利号:US-8633182-B2
优先权日:2012-05-30
标题:Indanyloxyphenylcyclopropanecarboxylic acids
发明人：HAMPRECHT DIETER; FRATTINI SARA; LINGARD IAIN; PETERS STEFAN
权利人:HAMPRECHT DIETER; FRATTINI SARA; LINGARD IAIN; PETERS STEFAN; BOEHRINGER INGELHEIM INT
摘要:The present invention relates to compounds of general formula I, n nwherein the groups R 1 , R 2 , R 3 , m and n are defined as in claim 1 , which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.

专利号:US-8785632-B2
优先权日:2004-08-26
标 题:Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors
发明人：CUI JINGRONG JEAN; FUNK LEE ANDREW; JIA LEI; KUNG PEI-PEI; MENG JERRY JIALUN; NAMBU MITCHELL DAVID; PAIRISH MASON ALAN; SHEN HONG; TRAN-DUBE MICHELLE
权利人:CUI JINGRONG JEAN; FUNK LEE ANDREW; JIA LEI; KUNG PEI-PEI; MENG JERRY JIALUN; NAMBU MITCHELL DAVID; PAIRISH MASON ALAN; SHEN HONG; TRAN-DUBE MICHELLE; AGOURON PHARMA; PFIZER
摘要:Enantiomerically pure compound of formula 1 n nare provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.