CAS: 108679-71-6; 3-Amino-2-Chlorobenzoic Acid

该化合物是一种多用途芳香化合物,其成分包括氨基氨基酸和箱状酸功能组,以及一个替代氯的替代体.这一结构使该化合物成为有机合成中有价值的中间体,特别是制药,农用化学品和特殊化学品.反应场所的存在使得能够进一步发挥作用,使在组合反应,异性循环形成和离心准备方面的应用成为可能.在标准条件下,该化合物的高度纯度和稳定性确保了研究和工业过程的一贯性能.该化合物通常以晶体固的形式供应,便于处理和精确测量.其定义明确的特性使它成为需要受控修改苯并硫衍生物的合成化学学家的可靠选择.

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3970-35-2 120100-15-4 53312-76-8

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CAS号3970-35-2 2-氯-3-硝基苯甲酸 | CAS号3970-40-9 2-氯-3-硝基甲苯 | CAS号249289-91-6 3-ACETYLAMINO-2... | CAS号56961-27-4 3-溴-2-氯苯甲酸 | CAS号120100-15-4 3-氨基-2-氯苯甲酸甲酯 | CAS号784143-99-3 6,7,8,9-tetrahy...

合成工艺路线路线简述

    📜2-氯-3-硝基甲苯置于potassium Permanganate,铂体系中,化学反应生成3-氨基-2-氯苯甲酸
    参考文献:The Closeness Of Fit Of Antibenzoate Antibodies About Haptens And The Orientation Of The Haptens In Combination1-3A
    标题:The Closeness Of Fit Of Antibenzoate Antibodies About Haptens And The Orientation Of The Haptens In Combination1-3A
    摘要:
    Doi:10.1021/ja01653A028

    专利信息


    专利号:US-5846993-A
    优先权日:1992-12-22
    标题:HIV protease inhibitors
    发明人：DRESSMAN BRUCE A; FRITZ JAMES E; KALDOR STEPHEN W; KALISH VINCENT J; REICH SIEGFRIED HEINZ; TATLOCK JOHN H; RODRIGUEZ MICHAEL J
    权利人:AGOURON PHARMA
    摘要:HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.

    专利号:US-6271235-B1
    优先权日:1992-12-22
    标题:HIV protease inhibitors
    发明人：DRESSMAN BRUCE A; FRITZ JAMES E; KALDOR STEPHEN W; KALISH VINCENT J; REICH SIEGFRIED HEINZ; RODRIGUEZ MICHAEL J; SHEPHERD TIMOTHY A; TATLOCK JOHN H; JUNGHEIM LOUIS NICKOLAUS
    权利人:AGOURON PHARMA
    摘要:HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.

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    合成参考文献


    摘要:Stewart, S. G., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 3, 442.
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