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专利信息
专利号:WO-2023203374-A1
优先权日:2022-04-20
标 题 :[1,2]selenazolo[2,3-a]pyridin-8-ium inhibitors of pyruvate kinase isoform m2
发明人:ARSENJANS PAVELS; DIMITRIJEVS PAVELS; MAKRECKA-KUKA MARINA
权利人:LATVIAN INST ORGANIC SYNTHESIS
摘要:The present invention relates to a novel isoselenazolopyridinium salts as anticancer agents by inhibiting pyruvate kinase isoform M2 (PKM2) activity, as well as methods of their manufacturing and use in different pharmaceutical compositions for the treatment of various diseases and disorders by administration of such substances.
专利号:US-9422244-B2
优先权日:2010-01-29
标 题 :Synthesis of substituted pyrazoline carboxamidine derivatives
发明人:VAN LOEVEZIJN ARNOLD; LANGE JOSEPHUS H M; BARF GERRIT A; DEN HARTOG ARNOLD P
权利人:VAN LOEVEZIJN ARNOLD; LANGE JOSEPHUS H M; BARF GERRIT A; DEN HARTOG ARNOLD P; ABBVIE BAHAMAS LTD
摘要:This invention relates to organic chemistry, in particular to processes for the preparation of pyrazoline carboxamidine derivatives of formula (I), known as potent 5-HT6 antagonists. The invention also relates to novel intermediates of these compounds. wherein the symbols have the meanings given in the description.
专利号:WO-2011092226-A1
优先权日:2010-01-29
标 题:Synthesis of substituted pyrazoline carboxamidine derivatives
专利号:US-2013060041-A1
优先权日:2010-01-29
标题:Synthesis of substituted pyrazoline carboxamidine derivatives
专利号:JP-2013518080-A
优先权日:2010-01-29
标 题:Synthesis of substituted pyrazoline carboxyamidine derivatives.
专利号:JP-5792195-B2
优先权日:2010-01-29
标题:Synthesis of substituted pyrazoline carboxyamidine derivatives.