CAS: 610791-05-4; Methyl 1-Boc-Azetidine-3-Carboxylate

相似化合物

100202-39-9 757239-60-4 142253-55-2

上下游产品

CAS号67-56-1 甲醇 | CAS号142253-55-2 1-B°C-氮杂环丁烷-3-羧酸 | CAS号18107-18-1 (三甲硅烷)重氮甲烷 | CAS号100202-39-9 氮杂环丁烷-3-甲酸甲酯盐酸盐 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号142253-56-3 3-羟甲基氮杂环丁烷-1-羧酸叔丁酯 | CAS号1340481-90-4 叔-丁基8-羟基-5-硫杂-2... | CAS号1340481-89-1 2-Methyl-2-prop... | CAS号1257293-79-0 3-(2-羟基丙-2-基)氮杂...

📜二碳酸二叔丁酯置于potassium Carbonate,Sodium Hydroxide体系中,用 四氢呋喃,水,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 48.0H,反应生成 1-(叔丁氧基羰基)氮杂环丁烷-3-甲酸甲酯
参考文献: Targeting Compounds[fr] Composés De Ciblage
标题: Targeting Compounds[fr] Composés De Ciblage
摘要:该披露提供了至少部分针对肝脏,肠道和/或肾脏的化合物,以及它们在治疗肝脏,肠道和/或肾脏疾病中的用途,如非酒精性脂肪肝,酒精性脂肪肝,肝细胞癌,肝硬化和乙型肝炎;和/或慢性肾脏疾病,肾小球疾病,如iga肾病,狼疮性肾炎或多囊肾病.这些化合物被认为对甲硫氨酰氨肽酶2具有活性.

专利信息

专利号:WO-2018108954-A1
优先权日:2016-12-12
标题 :Process for the preparation of 2-(3-(fluoromethyl)azetidin-1-yl)ethan-1-ol
发明人：GOSSELIN FRANCIS; LINGHU XIN
权利人:HOFFMANN LA ROCHE; GENENTECH INC
摘要:Methods of making 2-(3-(fluoromethyl)azetidin-1-yl)ethan-1-ol 9, an intermediate useful for the synthesis of estrogen receptor modulating compounds are described.

专利号:US-8785632-B2
优先权日:2004-08-26
标 题:Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors
发明人：CUI JINGRONG JEAN; FUNK LEE ANDREW; JIA LEI; KUNG PEI-PEI; MENG JERRY JIALUN; NAMBU MITCHELL DAVID; PAIRISH MASON ALAN; SHEN HONG; TRAN-DUBE MICHELLE
权利人:CUI JINGRONG JEAN; FUNK LEE ANDREW; JIA LEI; KUNG PEI-PEI; MENG JERRY JIALUN; NAMBU MITCHELL DAVID; PAIRISH MASON ALAN; SHEN HONG; TRAN-DUBE MICHELLE; AGOURON PHARMA; PFIZER
摘要:Enantiomerically pure compound of formula 1 n nare provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.