CAS: 52663-66-8; 2,2',3,3',4,5'-Hexachlorobiphenyl

该化合物是一种属于多氯联苯(PCBs)的氯化联苯化合物,其特点是六氯替代物,具有高度的化学稳定性和抗热降解的抗药性,该化合物由于其隔热性,历来被用于工业用途,如电流和阻燃剂;然而,其在环境中的持久性和潜在生物累积性已导致严格的监管控制;这一多氯联苯同族体的分析标准被用于环境测试和毒理学研究,以研究其行为,降解途径和生态影响;妥善处理和处置由于其分类为持久性有机污染物(POP),因此至关重要.

英文名称2,2',3,3',4,5'-Hexachlorobiphenyl
中文名称2,2',3,3',4,5'-六氯联苯
IUPAC名称1,2,3-trichloro-4-(2,3,5-trichlorophenyl)benzene
其它别名2,2',3,3',4,5'-Hexachlorobiphenyl; 2,3,4-2',3',5'-Hexachlorobiphenyl
CAS编号52663-66-8
MFCD编号:MFCD00792629
FDA UNII编号:6B52906N4U
分子式:C12H4Cl6分子量:360.88
产品CID: 2496356
产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃

相似结构搜索
产品信息参考;;;;
InChIKey: YFSLABAYQDPWPF-UHFFFAOYSA-N
1S/C12H4Cl6/c13-5-3-7(10(16)9(15)4-5)6-1-2-8(14)12(18)11(6)17/h1-4H
计算化学: 氢键受体数*氢键供体数0.0可旋转键数1.0

MSDS等安全信息

危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website.
安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)

上下游产品

1,2,3-trichloro-4-iodobenzene 1,2,5-trichloro-3-iodobenzene

合成工艺路线路线简述

📜2,2,3,3,4,4,5-七氯联苯反应生成 2,2',3,3',4,5'-六氯联苯
参考文献:Duebelbeis,D. O.;Kapila,S.;Clevenger,T.;Yanders,A. F.;Manahan,S. E.,Chemosphere,18,(1989) N-6,C. 101-108
标题:Duebelbeis,D. O.;Kapila,S.;Clevenger,T.;Yanders,A. F.;Manahan,S. E.,Chemosphere,18,(1989) N-6,C. 101-108