CAS: 5080-22-8; N-Isopropylhydroxylamine

该化合物是一种有机化合物,其特征是附于异丙基化合物组的氢氧基胺功能组,它看起来是淡黄色液体无色的,以其消毒剂和各种化学合成中的一种作用而著称,该化合物在水和极有机溶剂中溶解,这增强了其在化学反应中的效用.Isopropyhyoxylamine经常用于合成药品和农用化学品,以及用于分析化学,以探测某些金属离子.它具有中度毒性,需要小心处理和使用时采取适当的安全措施.此外,它可以参与各种反应,包括氧化和凝聚,使其在有机合成中成为多用途再生剂.其稳定性和再活性可能受到诸如pH和温度等因素的影响,这些因素是其应用中的重要考虑因素.

结构式图片

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

CAS号79-46-9 2-硝基丙烷 | CAS号113768-49-3 ethyl 2-isoprop... | CAS号127-06-0 丙酮肟 | CAS号7664-41-7 氨 | CAS号7647-01-0 盐酸 | CAS号144-62-7 草酸 | CAS号451-40-1 二苯乙酮 | CAS号112175-84-5 2-benzoyl-N-iso... | CAS号112175-86-7 2-isopropyl-4,5... | CAS号112175-85-6 O-[benzoyl(phen... | CAS号75-31-0 异丙胺 | CAS号73586-25-1 N,N'-dihydroxy-... | CAS号84418-31-5 1-[hydroxy(prop... | CAS号92030-73-4 3,3,6-trimethyl... | CAS号42065-76-9 propan-2-ylsulf... | CAS号7664-41-7 氨

合成工艺路线路线简述

    2-Isopropyl-3-Methyl-5-Oxo-2,5-Dihydro-Isoxazole-4-Carboxylic Acid Ethyl Ester置于盐酸,溶剂黄146体系中,用 水 作为反应溶剂,以96%的收率获得产物n-异丙基羟胺
    参考文献:An Efficient Synthesis Of N-Monoalkylated Hydroxylamines
    标题:An Efficient Synthesis Of N-Monoalkylated Hydroxylamines
    摘要:
    DOI:10.1016/s0040-4039(00)96265-8

    专利信息


    专利号:US-7807764-B2
    优先权日:2003-08-27
    标 题:Composition and process for the controlled synthesis of block copolymers
    发明人:WERMTER HENDRIK; SIMON DIRK; PFAENDNER RUDOLF
    权利人:CIBA SC HOLDING AG
    摘要:The present invention relates to a polymerizable composition comprising a) at least one ethylenically unsaturated monomer and b) at least one hydroxylamine of high molecular weight, preferably a long chain alkyl substituted hydroxylamine. Further aspects of the present invention are a process for polymerizing ethylenically unsaturated monomers, and the use of high molecular weight hydroxylamines for controlled polymerization.

    专利号:US-2004110228-A1
    优先权日:2002-04-01
    标 题:Combinatorial organic synthesis of unique biologically active compounds
    发明人:MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
    摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

    专利号:US-7041761-B2
    优先权日:2002-08-16
    标题:Functionalized monomers for synthesis of rubbery polymers
    发明人:HALASA ADEL FARHAN; HSU WEN-LIANG
    权利人:GOODYEAR TIRE & RUBBER
    摘要:The present invention relates to a process for synthesizing a rubbery polymer that comprises copolymerizing at least one conjugated diolefin monomer and at least one functionalized monomer in an organic solvent at a temperature which is within the range of 0° C. to about 150° C., wherein the polymerization is initiated with an anionic initiator, wherein the polymerization is conducted in the absence of conventional polar modifiers, and wherein the functionalized monomer is of the structural formula: n nwherein the R′ groups in repeat units and in different repeat units can be the same or different and represent hydrogen atoms or alkyl groups containing from 1 to about 4 carbon atoms, wherein x represents an integer from 1 to about 10, and wherein the R groups in repeat units and in different repeat units can be the same or different and represent alkyl groups containing from 1 to about 10 carbon atoms or alkoxy groups containing from 1 to about 10 carbon atoms.

    专利号:US-2005192265-A1
    优先权日:2003-03-20
    标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
    发明人:THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
    摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

    专利号:WO-2024256666-A1
    优先权日:2023-06-16
    标 题:Production of synthesis gas by partial oxidation of a hydrocarbon stream containing plastic liquefaction oil
    发明人:ADAM CINDY; CHOFFAT ALEXANDRINE; MINOUX DELPHINE; VAN LOOK EMMANUEL; BRETON CHRISTOPHE
    权利人:TOTALENERGIES ONETECH
    摘要:The invention relates to a process for the production of synthesis gas by partial oxidation from a hydrocarbon stream containing plastic liquefaction oil, comprising: a) providing a composition stabilized against premature polymerization comprising: 1) a hydrocarbon stream containing at least 2 wt% of plastic liquefaction oil which is containing contaminants, the remaining part of said hydrocarbon stream being a diluent, 2) at least one additive capable to reduce gums formation or buildup, 3) optionally at least one additive which is a dispersant agent, b) an optional purification step to trap silicon and/or metals and/or phosphorous and/or halogenates over at least one trap to obtain a purified composition, c) gasifying by partial oxidation the stabilized composition provided in step (a), or the purified composition provided in step (b), in a partial oxidation gasification unit to produce synthesis gas comprising at least dihydrogen, carbon monoxide, and carbon dioxide.

    专利号:US-6906056-B2
    优先权日:1998-06-22
    标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
    发明人:THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
    权利人:LILLY CO ELI
    摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
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    合成参考文献


    摘要:Merino, P., Science of Synthesis Knowledge Updates, (2010) 4, 354.
    摘要:Wessjohann, L. A.; Kaluđerović, G. N.; Neves Filho, R. A. W.; Morejon, M. C.; Lemanski, G.; Ziegler, T., Science of Synthesis: Multicomponent Reactions, (2013) 1, 439.
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