CAS: 479-23-2; Cholanthrene
- 英文名称Cholanthrene
- 中文名称1,2-二氢苯[J]并苊
- IUPAC名称1,2-dihydrocyclopenta[ij]tetraphene
- 其它别名1,2-Dihydro-Benz(J)Aceanthrylen; 1,2-Dihydroxybenz[j]Aceanthrylene; 7,8-Dimethylenebenz(A)Anthracene; Benz(7,8)Aceanthrene; Cholanthrene; 1,2-Dihydrobenz[j]Aceanthrylene; 1,2-Dihydrobenzo[j]Aceanthrylene; Benz[j]Aceanthrylene, 1,2-Dihydro-
- CAS编号479-23-2
- MFCD编号:MFCD00215931
- EINECS号:207-528-2
- FDA UNII编号:429L45KABE
- 分子式:C20H14分子量:254.33
- 产品CID: 1475006
- 产品分类有机原料 → 苯类化合物 → 菲及其衍生物
物理性质
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明IDENTIFICATION AND USE: Cholanthrene is a solid. It is a polycyclic aromatic hydrocarbon used in biochemical research. HUMAN EXPOSURE AND TOXICITY: There are no data available. ANIMAL STUDIES: Cholanthrene was a moderate tumor-initiator in mouse skin with maximal tumor yields of 6.90 and 8.86 tumors per mouse at 200 and 600 nmol doses, respectively, after 20 weeks of promotion. The introduction of a methyl substituent at the non-benzo ring bay-region position of cholanthrene (i.e. carbon atom 6) dramatically increased tumor-initiating activity in mice. Studies on the mutagenicity and metabolism of benz(j)aceanthrylene are reported in Salmonella. The activity spectrum over the 5 Ames tester strains is similar to that of benzo(a)pyrene, and the dose-response curves for strain TA98 are comparable. Benz(j)aceanthrylene is a frame-shift mutagen requiring metabolic activation.
- 危险类别码Emergency treatment: Polynuclear aromatic hydrocarbons; Acute toxicity of PAHs is low; May cause photosensitivity; May cause cancer after chronic exposure; [HSDB] See POLYCYCLIC AROMATIC HYDROCARBONS.
上下游产品
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📜6-乙酰氧基胆蒽置于氢碘酸,次磷酸,溶剂黄146体系中,化学反应 0.03H,以80%的收率获得产物1,2-二氢苯[j]并苊
参考文献:Synthesis Of Cholanthrene And 6-Methylcholanthrene,Biologically Active Analogs Of The Potent Carcinogen 3-Methylcholanthrene
标题:Synthesis Of Cholanthrene And 6-Methylcholanthrene,Biologically Active Analogs Of The Potent Carcinogen 3-Methylcholanthrene
摘要:
DOI:10.1021/jo00378A025
海关参考信息
- 2902600000-乙苯
2902902000-精萘 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2003162992-A1
优先权日:2001-12-14
标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
发明人：WATANABE KYOICHI A; DU JINFA
摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.
专利号:US-7429658-B2
优先权日:2003-09-11
标题 :Synthesis of protected pyrrolobenzodiazepines
发明人：HOWARD PHILIP; MASTERSON LUKE
权利人:SPIROGEN LTD
摘要:A method of synthesis of a N-10 protected PBD compound of formula (I): n nvia an intermediate of formula (II) or formula (V):
专利号:US-9006425-B2
优先权日:2009-03-18
标题:Aluminum complexes and their use in the synthesis of cyclic carbonates
发明人：NORTH MICHAEL
权利人:NORTH MICHAEL; UNIV YORK
摘要:Dimeric aluminum catalysts of formula I: and their use in catalyzing the synthesis of cyclic carbonates from epoxides and carbon dioxide.
专利号:US-9242955-B2
优先权日:2007-04-25
标题 :Synthesis of cyclic carbonates
发明人：NORTH MICHAEL
权利人:NORTH MICHAEL; UNIV YORK
摘要:A process for the production of cyclic carbonates comprising contacting an epoxide with carbon dioxide in the presence of a dimeric aluminum(salen) catalyst, and a co-catalyst capable of supplying Y − , where Y is selected from Cl, Br and I, where the dimeric aluminum(salen) catalyst is of formula I:
专利号:US-9273024-B2
优先权日:2008-03-07
标 题 :Synthesis of cyclic carbonates
发明人：NORTH MICHAEL
权利人:UNIV NEW CASTLE UPON TYNE; UNIV YORK
摘要:A dimeric aluminum(salen) catalyst of formula I: n nwherein: (a) at least one R group is selected from L-A, and/or (b) at least one of X group is a divalent C3-7 heterocyclene group, containing a ring atom which is a quaternary nitrogen atom paired with a counterion selected from Cl, Br and I; and/or (c) at least one X group is a C2-5 alkylene chain or a C1-3 bisoxyalkylene chain, substituted by a group -Q-L-A; and/orn n(ii) (a) one R group is L-A′, or (b) one X group is a divalent C3-7 heterocyclene group, containing a ring atom which is a quaternary nitrogen forming part of an ammonium linking group bound to a solid support and paired with a counterion selected from Cl, Br and I; or (c) one X group is a C2-5 alkylene chain or a C1-3 bisoxyalkylene chain, substituted by a group -Q-L-A′.
专利号:WO-2008132474-A1
优先权日:2007-04-25
标 题:Synthesis of cyclic carbonates in the presence of dimeric aluminium (salen) catalysts
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. 11th Edition. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. 2004., p. 911
摘要:American Conference of Governmental Industrial Hygienists TLVs and BEIs. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. Cincinnati, OH 2016, p. 118
摘要:RIGDON RH, OMER S. Tumors after implants of methyl-cholanthrene in ducks. Arch Pathol. 1961 Jun;71():641–5.
摘要:RIGDON RH. Pulmonary neoplasms produced by methyl-cholanthrene in the white Pekin duck. Cancer Res. 1961 May;21():571–4.
📝 需求与反馈
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