CAS: 4430-31-3; Octahydro-2H-Chromen-2-One

八氢海水蛋白的分子结构具有一种饱和的六人环状,该环状环状五人,有助于其独特的特性.它溶于乙醇和乙醚等有机溶剂,但水溶性有限.它主要用于香味工业,因为其香味诱人,还用于各种化妆品的配制.此外,它也用于食品工业,作为调味剂.一般认为,该化合物具有低毒性,但处理和使用时必须查阅安全数据.其化学稳定性和令人愉快的芳香使得它成为工业和消费产品中有价值的化合物.

结构式图片

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59498-98-5 4350-84-9 21898-84-0

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

CAS号1124-63-6 3-环己基-1-丙醇 | CAS号60211-12-3 2-(3-hydroxypro... | CAS号22118-00-9 2,3,4,5,6,7-Hex... | CAS号699-61-6 1-氧杂螺[4.5]癸-2-酮

合成工艺路线路线简述

    环己酮二甲基腙置于正丁基锂,Samarium Diiodide,Amberlyte Ir 120,异丙硫醇体系中,用 四氢呋喃,正己烷,丙酮 作为反应溶剂,化学反应 20.5H,反应生成 2H-1-苯并吡喃-2-酮,八氢-,反-
    参考文献:通过一锅顺序缩醛化,Tishchenko反应和by离子和硫醇的协同催化内酯化作用,从5-氧代烷醛立体选择性合成δ-内酯.
    标题:通过一锅顺序缩醛化,Tishchenko反应和by离子和硫醇的协同催化内酯化作用,从5-氧代烷醛立体选择性合成δ-内酯.
    摘要:通过sa离子和硫醇的协同催化,一系列5-氧代烷醛以有效和立体选择性的方式转化为(取代的)δ-内酯.这一一锅法包括一系列缩醛化,Tishchenko反应和内酯化.与醇相比,有意使用硫醇有利于促进催化循环.提出了反应机理和立体化学,并得到了一些实验证据的支持.sa离子/硫醇共催化反应显示出远程控制的特征,适用于旋光性δ-内酯的不对称合成.这项研究还证明了两种昆虫信息素(2S,5R)-2-甲基己内酯和(R)-十六烷内酯的合成,
    DOI:10.1021/jo016058T

    海关参考信息

    专利信息


    专利号:US-8440608-B2
    优先权日:2004-08-06
    标题:Beta-substituted tetrandropyrana (on) s and method for the synthesis and the use thereof
    发明人:MANE JEAN; CHANOT JEAN-JACQUES; SCHROEDER MARTIN
    权利人:MANE JEAN; CHANOT JEAN-JACQUES; SCHROEDER MARTIN; MANE FILS V
    摘要:The invention relates, in particular to a tetrahydropyran(on) compound which is substituted in position beta with respect to a cycle oxygen of formula (I), wherein a substituent R is a linear alkyl radical in C2:C10 including, (CH 3 ) 2 CH— or C 6 H 5 —(CH 2 ) m —, with m=0 or 1, or formula (II), wherein A is —CH 2 — or —CO—, in the form of an odorant and to a method for the synthesis thereof by reducing oxo-ester. The use of the inventive compound in composition such as perfumery compositions in the ordinary sense of the term i.e. topic, in particular cosmetic compositions and care products.

    专利号:US-10647942-B2
    优先权日:2016-12-22
    标题:Fragrance and flavor materials
    发明人:BLANDINO MAUREEN; LANKIN MICHAEL E
    权利人:TAKASAGO PERFUMERY CO LTD
    摘要:The present disclosure is directed to the synthesis and application of undecavertol derivatives having unique and desired flavor and/or fragrant characteristics. The compounds of the present disclosure can be employed alone or incorporated as fragrance or flavor ingredients in fragrance or flavor compositions. The present disclosure is also directed to consumer products comprising such derivatives and/or fragrance or flavor compositions.

    专利号:US-12114681-B2
    优先权日:2018-06-04
    标题:Fragrance and flavor materials
    发明人:BLANDINO MAUREEN; TANUMA KENJI
    权利人:TAKASAGO PERFUMERY CO LTD
    摘要:The synthesis and application of compounds having unique and desired flavor and/or fragrance characteristics are provided herein. The compounds herein can be employed alone or incorporated as fragrance or flavor ingredients in fragrance or flavor compositions. The application is also directed to consumer products comprising such derivatives and/or fragrance or flavor compositions.

    专利号:US-2021198229-A1
    优先权日:2018-03-08
    标 题 :Fragrance and flavor materials from 1-(2-hydroxy-4-methylcyclohexyl)-ethanone
    发明人:DICKERSON THALIA S; LOMBARDO LOUIS J; LANKIN MICHAEL E
    权利人:TAKASAGO PERFUMERY CO LTD
    摘要:The present disclosure is directed to 1-(2-hydroxy-4-methycyclohexyl)-ethanone derivatives having unique and desired flavor and/or fragrance characteristics, as well as the synthesis and application of the derivatives. The compounds of the present disclosure can be employed alone or incorporated as fragrance or flavor ingredients to modify or enhance already existing fragrance compositions, solvents, media, and the like.

    专利号:US-2020062687-A1
    优先权日:2016-12-22
    标 题:Fragrance and flavor materials
    发明人:BLANDINO MAUREEN; LANKIN MICHAEL E
    权利人:TAKASAGO PERFUMERY CO LTD
    摘要:The present disclosure is directed to the synthesis and application of ethyl linalool derivatives having unique and desired flavor and/or fragrance characteristics. The compounds of the present disclosure can be employed alone or incorporated as fragrance or flavor ingredients in fragrance or flavor compositions. The present disclosure is also directed to consumer products comprising such derivatives and/or fragrance or flavor compositions.

    专利号:US-2019350826-A1
    优先权日:2016-12-22
    标题:Fragrance and flavor materials
    发明人:BLANDINO MAUREEN; LANKIN MICHAEL E
    权利人:TAKASAGO PERFUMERY CO LTD
    摘要:The present disclosure is directed to the synthesis and application of an ethyl linalool derivative having unique and desired flavor and/or fragrant characteristics. Specifically, the compound is represented by Formula (I). The compound of Formula (I) can be employed alone or incorporated as fragrance or flavor ingredients in fragrance or flavor compositions. The present disclosure is also directed to consumer products comprising such derivatives and/or fragrance or flavor compositions.
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    主要参考文献

    参考标题:Stereocontrolled Synthesis Of Substituted Bicyclic Ethers Through Oxy-Favorskii Rearrangement: Total Synthesis Of (+/-)-Communiol E
    作者:Shoji Kobayashi,Tatsuhiro Kinoshita,Takuji Kawamoto,Masato Wada,Hiroyuki Kuroda,Araki Masuyama,Ilhyong Ryu |发布日期:2011.9.2
    摘要:The Potential Of The Oxy-Favorskii Rearrangement To Form Branched Cis-Fused Bicyclic Ethers Was Explored. Both Tertiary And Quaternary Centers Were Constructed In Highly Stereospecific Manners. Methanol And Primary Amines Were Effective Nucleophiles For The Rearrangement. The Total Synthesis Of (+/-)-Communiol E Was Achieved Based On This Method.

    合成参考文献


    摘要:Chciuk, T. V.; Flowers, R. A.; Flowers, R. A., Science of Synthesis Knowledge Updates, (2016) 2, 217.
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