CAS: 37451-68-6; Tetrabutyl Ammonium Chloride Xhydrate

该化合物是一种四丁基氨盐,其特征是四丁基联苯基盐,附在中央氮原子上,使其变成一个散装的碳化物,通常会以白色晶状固体或无色液体形式出现,视其形式和纯度而定.TBAC在乙酮和乙醇等极有机溶剂中是可溶性,但由于其具有氢丁基化合物,但在水中溶性有限.该化合物经常被用作有机合成的分阶段转移催化剂,促进分期转移离子,从而提高反应率和产量.此外,TBAC可以作为各种化学反应的试剂,包括涉及核生殖器替代的试剂.必须谨慎处理氯化四丁基聚氨,因为它可能会对皮肤和眼睛产生刺激.在与该化学品打交道时,应当观察适当的安全措施,包括使用个人防护设备.总的来说,TBAC在学术和工业环境中都对其独特的特性和易变性进行估价.

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    专利号:US-2009137828-A1
    优先权日:2005-08-18
    标 题 :Synthesis of 1A-Fluoro-25-Hydroxy-16-23E-Diene-26,27-Bishomo-20-Epi-Cholecalciferol
    发明人:USKOKOVIC MILAN R; MARCZAK STANISLAW; LOO RALF; VAN DER SLUIS MARCEL; JANKOWSKI PAWEL; MAEHR HUBERT
    权利人:BIOXELL SPA
    摘要:The invention provides a method of producing 20-methyl vitamin D3 compounds of formula (I). The method includes allylic and olefin oxidation, de-carbonylation, carbonyl reduction, fluoride substitution, epoxide deoxygenation, and Wittig-type couplings.

    专利号:US-12071422-B2
    优先权日:2022-02-07
    标 题 :Process for synthesis of quinazoline compounds
    发明人:LEBL RENE; LIM NGIAP KIE; MEIER ROLAND CHRISTOPH; ORCEL UGO JONATHAN; SEDELMEIER JOERG; SHEN JEFF; SIROIS LAUREN ELIZABETH; TIMMERMAN JACOB C; TRACHSEL ETIENNE; WHITE NICHOLAS ANDREW; XU JIE; ZHANG HAIMING; BACHMANN STEPHAN; BASS THOMAS MICHAEL; BIGLER RAPHAEL; BURKHARD JOHANNES ADRIAN; CLAGG KYLE BRADLEY PASCUAL; GOSSELIN FRANCIS; HAN CHONG; KALDRE DAINIS; KELLY SEAN M; HEROLD SEBASTIAN; LEITNER CHRISTIAN
    权利人:GENENTECH INC; HOFFMANN LA ROCHE
    摘要:Provided herein are methods to synthesize compounds useful in the treatment of cancer where such compounds comprise a quinazolinyl core moiety and at least one stereoisomeric or atropisomeric moiety.

    专利号:AU-2006279331-A1
    优先权日:2005-08-18
    标 题 :Synthesis of 1alpha-fluoro-25-hydroxy-16-23e-diene-26,27-bishomo-20-epi-cholecalciferol

    专利号:US-7678462-B2
    优先权日:1999-06-10
    标 题:Spin-on-glass anti-reflective coatings for photolithography
    发明人:KENNEDY JOSEPH; BALDWIN TERESA; HACKER NIGEL P; SPEAR RICHARD
    权利人:HONEYWELL INT INC
    摘要:Anti-reflective coating materials for deep ultraviolet photolithography include one or more organic light-absorbing compounds incorporated into spin-on-glass materials. Suitable absorbing compounds are strongly absorbing over wavelength ranges around wavelengths such as 365 nm, 248 nm, and 193 nm that may be used in photolithography. A method of making absorbing spin-on-glass materials includes combining one or more organic absorbing compounds with alkoxysilane or halosilane reactants during synthesis of the spin-on-glass materials.

    专利号:US-9839642-B2
    优先权日:2014-05-09
    标 题:Beta-tetrazolyl-propionic acids as metallo-beta-lactamase inhibitors
    发明人:TANG HAIFENG; YANG SHU-WEI; MANDAL MIHIR; SU JING; LI GUOQING; PAN WEIDONG; TANG HAIQUN; DEJESUS REYNALDA; PAN JIANPING; HAGMANN WILLIAM; DING FA-XIANG; XIAO LI; PASTERNAK ALEXANDER; HUANG YUHUA; DONG SHUZHI; YANG DEXI
    权利人:MERCK SHARP & DOHME
    摘要:The present invention relates to compounds of formula I that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.

    专利号:US-12187755-B2
    优先权日:2014-05-30
    标题 :Minimal saponin analogues, synthesis and use thereof
    发明人:GIN DAVID Y; CHEA ERIC K; FERNANDEZ-TEJADA ALBERTO; TAN DEREK S; LEWIS JASON S; GARDNER JEFFREY R; PILLARSETTY NAGAVARAKISHORE
    权利人:MEMORIAL SLOAN KETTERING CANCER CENTER
    摘要:Truncated triterpene saponin analogues containing a trisaccharide or tetrasaccharide ester are disclosed. Also disclosed are pharmaceutical compositions comprising truncated saponin analogues and synthetic methods of producing the truncated saponin analogues. Another aspect of the present application relates to a method for immunizing a subject, comprising administering to the subject the pharmaceutical composition comprising a minimal saponin analogue and an antigen.

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    摘要:Lubell, W. D.; St-Cyr, D. J.; Dufour-Gallant, J.; Hopewell, R.; Boutard, N.; Kassem, T.; Dörr, A.; Zelli, R., Science of Synthesis Knowledge Updates, (2013) 1, 315.
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