CAS: 302-40-9; 2-(Diethylamino)Ethyl 2-Hydroxy-2,2-Diphenylacetate

上下游产品

CAS号869-24-9 2-二乙氨基氯乙烷盐酸盐 | CAS号5928-68-7 二苯基乙醇酸钾 | CAS号76-93-7 二苯乙醇酸 | CAS号100-35-6 N,N-二乙基氯乙胺 | CAS号100-37-8 二乙氨基乙醇 | CAS号2902-98-9 2-氯-2,2-二苯基乙酰氯 | CAS号52182-15-7 三苯乙醇酸乙酯 | CAS号3166-62-9 溴甲贝那替秦 | CAS号6699-38-3 2-(diethylamino... | CAS号6422-50-0 triethyl-[2-(2-...

📜阿的芬宁置于sodium Carbonate,Potassium Hydroxide体系中,用 甲醇,1,2-二氯乙烷 作为反应溶剂,化学反应 48.0H,反应生成 贝那替嗪
参考文献:蓝光辐照增强了芳基重氮乙酸酯与硼酸的室温偶联.
标题:蓝光辐照增强了芳基重氮乙酸酯与硼酸的室温偶联.
摘要:据报道可见光促进的光化学方案用于芳基重氮乙酸酯与硼酸的偶联.与没有光照的相同方案相比,这种光化学反应显示出极大的增强.除少数情况外,在黑暗(热过程)中的室温耦合通常不起作用.如果这样做的话,很可能还涉及到游离卡宾作为关键中间体.可替代地,光化学反应显示出广泛的范围,可以在空气中进行并且耐受各种各样的官能团.反应进化监测,Dft计算和控制实验已用于评估这种复杂机制的主要方面.具有生物活性的分子阿迪芬,苯那西嗪和阿普生已经被制备为合成应用的实例.
DOI:10.1002/chem.201905812

专利信息

专利号:US-2008214827-A1
优先权日:2004-02-03
标 题:Synthesis of Cyanoimino-Benzoimidazoles
发明人：GOEHRING R RICHARD; WHITEHEAD JOHN; SHAO BIN
权利人:EURO CELTIQUE SA
摘要:Disclosed in certain embodiments is a process for synthesizing a compound of formula (V) and salts thereof.

专利号:US-7309799-B2
优先权日:2004-06-01
标 题:Methods for the synthesis of milnacipran and congeners thereof
发明人：BUCHWALD STEPHEN L; SWAGER TIMOTHY M; RARIY ROMAN V
权利人:COLLEGIUM PHARMACEUTICAL INC
摘要:One aspect of the present invention relates to methods for synthesizing milnacipran or congeners thereof. Another aspect of the present invention relates to asymmetric methods for synthesizing enantiomerically enriched milnacipran or congeners thereof. The present invention also relates to methods for synthesizing intermediates useful in the non-asymmetric or asymmetric methods for synthesizing enantiomerically enriched milnacipran or congeners thereof.

专利号:US-7749985-B2
优先权日:2006-09-15
标 题 :Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
发明人：GALLOP MARK A; XU FENG; PHAN THU; DILIP USHA; PENG GE
权利人:XENOPORT INC
摘要:Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphinic acid and analogs thereof, methods of making acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphinic acid and analogs thereof, methods of using acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphinic acid and analogs thereof, and pharmaceutical compositions comprising acyloxyalkyl carbamate prodrugs 3-aminopropylphosphinic acid and analogs thereof for treating diseases or disorders such as mild cognitive impairment, cognitive impairment associated with Alzheimer's disease Alzheimer's disease, depression, anxiety, and epilepsy are disclosed. Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphinic acid and analogs thereof, which are suitable for oral administration and sustained release oral dosage forms are also disclosed.

专利号:US-2005282898-A1
优先权日:2004-06-01
标 题 :Methods for the synthesis of milnacipran and congeners thereof

专利号:CA-2555219-A1
优先权日:2004-02-03
标 题 :Synthesis of cyanoimino-benzoimidazoles

专利号:US-2023271983-A1
优先权日:2020-07-29
标题 :Functionalized isonitriles and products, preparation and uses thereof
发明人：SOTELO PÉREZ EDDY; AZUAJE GUERRERO JHONNY ALBERTO; MAJELLARO MARIA
权利人:UNIV SANTIAGO COMPOSTELA
摘要:The present invention relates to functionalized isonitrile compounds, formed by means of multicomponent environmentally friendly reactions, suitable for coupling to functional molecules such as biomolecules, APIs, chromophore and fluorophore molecules. The invention also relates to conjugates between said isonitrile compounds and functional molecules, which are useful in the synthesis of pharmaceutic drugs or tools, fluorescent molecules and labels, polymeric smart materials. The invention furthermore provides a kit for the in-vitro preparation of the functionalized isontrile compounds and conjugates. The invention also contemplates the medical use of said compounds and conjugates.