CAS: 240417-00-9; 2-Diphenylphosphino-2'-(N,N-Dimethylamino)Biphenyl

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CAS号15475-27-1 二苯基磷酸钾 | CAS号712350-51-1 (2'-(dimethylam... | CAS号583-55-1 2-溴碘苯 | CAS号88652-74-8 1-bromo-2-diphe... | CAS号4559-70-0 二苯基磷氧 | CAS号829-85-6 二苯基膦 | CAS号62336-24-7 (2-溴苯基)二苯基膦

Potassium Diphenylphosphine 以 四氢呋喃 用作溶剂,化学反应 36.0H,反应生成2-二苯基磷-2'-(N,N-二甲氨基)联苯
参考文献:的合成ñ,P,-小号,P-,P,P-和小号,P,小号-Ligands使用环钯配合物的反应与kpph 2
标题:的合成ñ,P,-小号,P-,P,P-和小号,P,小号-Ligands使用环钯配合物的反应与kpph 2
摘要:易于获得的具有(sp 2)c-pd键的空气和湿气稳定的二聚氯桥cn-,Cs-和cp-环钯配合物可与4.5当量反应.用thf中的kpph 2生成相应的p,N-,P,S-和p,P-双齿配体,产率为35-63%.该phosphination方法适用于五元和由(衍生六元钯环小号)-ñ,ñ-二甲基-1-苯基乙胺,(小号)-4-叔-丁基-2-苯基-2-恶唑啉,苄基甲基硫醚,苄基二苯基膦,2-苄基吡啶和n,N-二甲基联苯-2-胺.反应1.2当量.用由1,3-双(甲硫基甲基)苯制得的scs-钳形环钯配合物制备的kpph 2,以49%的收率提供了相应的s,P,S-三齿配体.
Doi:10.1016/j.Jorganchem.2013.07.078

专利信息

专利号:US-2003083352-A1
优先权日:2000-07-31
标 题 :Synthesis of imidazole intermediates
发明人：HELAL CHRISTOPHER J
权利人:PFIZER
摘要:The invention provides a method for synthesis of compounds of formula n n n wherein R 1 and R 19 are as defined. Compounds of formula 12 are useful as intermediates for synthesizing compounds having pharmacological activity inhibiting cdk5, cdk2, and GSK-3.

专利号:US-6958420-B2
优先权日:2002-07-19
标题:Synthesis of aminoarylboronic esters and substituted anilines from arenes via catalytic C-H activation/borylation/amination and uses thereof
发明人：MALECZKA JR ROBERT E; SMITH III MILTON R; HOLMES DANIEL
权利人:UNIV MICHIGAN STATE
摘要:A process is described for synthesizing aminoarylboronic esters of the general formula n n nwherein R, R 2 , and R 3 are each an alkyl, aryl, vinyl, alkoxy, carboxylic esters, amides, or halogen; Ar is any variety of phenyl, naphthyl, anthracyl, heteroaryl; and R 1 is alkyl, hydrogen, or aryl. The aminoarylboronic esters are produced via the metal-catalyzed coupling of arylboronic esters of the general formula n n nwherein R and R 1 are any non-interfering group and X is chloro, bromo, iodo, triflates, or nonaflates to amines (primary and secondary). In particular, a process is described for the synthesis of the aminoarylboronic esters via a step-wise or tandem process in which one catalytic event is a metal-catalyzed borylation and the other catalytic event is a metal-catalyzed amination.

专利号:US-2024336649-A1
优先权日:2021-06-21
标 题 :Synthesis of covalent protein dimers that can inhibit myc-driven transcription
发明人：LOAS ANDREI; PENTELUTE BRADLEY L; POMPLUN SEBASTIAN; JBARA MUHAMMAD; SCHISSEL CARLY KATHERINE; RODRIQUEZ JACOB JOSHUA LEE; BUCHWALD STEPHEN LEFFLER; BOIJA ANN; KLEIN ISAAC; HAWKEN SUSANA WILSON; LI CHARLES HAN
权利人:MASSACHUSETTS INST TECHNOLOGY; WHITEHEAD INSTITUTE OF BIOMEDICAL RES
摘要:The disclosure relates to covalent protein dimers of MYC, MAX, and Omomyc; pharmaceutical compositions comprising the covalent protein dimers; methods of making the covalent protein dimers; and methods of treating disorders associated with MYC dysregulation (e.g., cancer) with the covalent protein dimers.

专利号:US-11718584-B2
优先权日:2019-02-22
标题 :Process for the synthesis anthranilic diamide compounds and intermediates thereof
发明人：KARRI PHANEENDRASAI; PABBA JAGADISH; SHINDE BHARAT UTTAMRAO; KALWAGHE AMOL DNYANESHWAR; MADHAVRAO KAMBLE MARUTI; KLAUSENER ALEXANDER G M; PANMAND DEEPAK SHANKAR
权利人:PI INDUSTRIES LTD
摘要:The present invention disclosed a process for the synthesis of anthranilic diamide compound of formula (I), n n n n n n n n n n wherein, R 1 , R 2 , R 3a , R 3b , R 3c , R 4 , R 5 , R 6 and Z are as defined in the detailed description. The process comprising the step of obtaining a mono- or dicyano substituted aniline compound of formula (IV) which is then converted to an anthranilic acid compound of formula (V) or an anthranilic amide compound of formula (Va). Further, the compound of formula (VI) can be optionally synthesized from compound of formula (IV or V or Va)

专利号:US-2023150994-A1
优先权日:2020-04-07
标 题:Methods for synthesis of chk1 inhibitors
发明人：SCHWAEBE MICHAEL; ROSNER THORSTEN; ZHAO DALIAN; MILLER ROSS; DULINA RICH; HUMORA MICHAEL; GOTTSCHLING STEPHEN E
权利人:SIERRA ONCOLOGY INC
摘要:The present technology relates to processes, compounds, compositions, and methods useful for coupling reactions. Also, the present disclosure provides for novel intermediates, compositions of matter, and processes relating to the Chk1 inhibitor, SRA737.

专利号:US-2004024237-A1
优先权日:2002-07-19
标 题:Synthesis of aminoarylboronic esters and substituted anilines from arenes via catalytic C-H activation/borylation/amination and uses thereof