📜1-(2-溴-1,1-二甲氧基乙基)-4-甲基苯置于silver Tetrafluoroborate体系中,用 甲醇 用作溶剂,化学反应生成对甲苯基乙酸甲酯 参考文献:Giordano,Claudio; Castaldi,Graziano; Casagrande,Francesco,Journal Of The Chemical Society. Perkin Transactions I,1982,# 11,P. 2575-2582 标题:Giordano,Claudio; Castaldi,Graziano; Casagrande,Francesco,Journal Of The Chemical Society. Perkin Transactions I,1982,# 11,P. 2575-2582
专利号:WO-2014138989-A1 优先权日:2013-03-15 标 题 :Method and intermediates for the synthesis of hydroxamic acid compounds 发明人:VAISBURG ARKADII; RAEPPEL FRANCK; ROY SIMON; ZHOU NANCY Z 权利人:METHYLGENE INC 摘要:Methods are disclosed for making a compound of formula and intermediates therefor, where R is aryl or heteroaryl, and L is C3_8alkylene, wherein each of R, L, and the illustrated phenyl group are independently optionally substituted with one or more substituents selected from the group consisting of C].6alkyl, Ci.6alkoxy, CF3, CHF2, CH2F, fluoro, and cyano, which methods can avoid the use of iodo-phenyl esters, or aryl alkynes, or both, or, in which synthetic methods at least one of the intermediates is a solid at room temperature that does not require purification by chromatography.
专利号:US-10287225-B2 优先权日:2015-05-13 标 题:Chain multiyne compound, preparation method and application thereof 发明人:XIA HAIPING; ZHUO QINGDE; LIN JIANFENG; ZHOU XIAOXI; CHEN ZHIXIN; SHAO YIFAN; ZHANG HONG; HE XUMIN 权利人:UNIV XIAMEN 摘要:The present invention relates to fields of organic chemistry and organometallic chemistry. The present invention discloses a chain multiyne compound, a preparation method thereof and an application in synthesizing a fused-ring metallacyclic compound. A structure of the chain multiyne compound in the present invention is shown as Formula I below. The present invention also provides a preparation method of the chain multiyne compound and an application thereof in a synthesis of a fused-ring metallacyclic compound. The chain multiyne compound disclosed in the present invention has multiple functional groups and the structure of the chain multiyne compound is adjustable. The chain multiyne compound can also be used to synthesize the fused-ring metallacyclic compound efficiently. The preparation method of the chain multiyne compound disclosed in the present invention is simple, which can be used to prepare the chain multiyne compound rapidly and efficiently.
参考标题:An Approach To Spirooxindoles Via Palladium-Catalyzed Remote C-H Activation And Dual Alkylation With Ch2Br2 作者:Changdong Shao,Zhuo Wu,Xiaoming Ji,Bo Zhou,Yanghui Zhang 摘要:A Facile And Efficient Approach For The Synthesis Of Spirooxindoles Has Been Developed Via The Coupling Of Spirocyclic C, C-Palladacycles With Ch2Br2. The Key Spirocyclic Palladacycles Are Generated Catalytically Via Intramolecular Remote C-H Activation. A Range Of Spirooxindoles Can Be Synthesized In Good To Excellent Yields From Readily Available Starting Materials.
合成参考文献
摘要:Bietti, M.; Dénès, F., Science of Synthesis, (2021) , 542. 摘要:Bao, Z.; Wang, J., Science of Synthesis: Knowledge Updates, (2023) 2, 22. 摘要:Kiyokawa, K., Science of Synthesis: Hypervalent Halogens in Organic Synthesis, (2025) .