CAS: 23786-13-2; Methyl 2-(P-Tolyl)Acetate

该化合物是一种酯类化合物,通常用作有机合成和香味应用中的中间体,其化学结构具有一个附属于四甲基苯乙酸混合物的甲基酯组,为进一步衍生提供了稳定性和回活动性;该化合物因其一贯纯度和明确界定的特性而在生产精细化学品,药品和芳香化合物方面所发挥的作用而受到重视;在普通有机溶剂中具有低挥发性和高溶性,便于其在受控反应中使用;甲基替代物的存在增强了其消毒和电子特性,使其适合专门合成途径;建议适当处理和储存以保持其完整性.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号67-56-1 甲醇 | CAS号201230-82-2 carbon monoxide | CAS号104-81-4 4-甲基溴苄 | CAS号4498-99-1 4-甲基苄基硫醇 | CAS号122-00-9 对甲基苯乙酮 | CAS号149-73-5 原甲酸三甲酯 | CAS号622-47-9 对甲苯乙酸 | CAS号766-97-2 4-乙炔基甲苯 | CAS号7664-93-9 硫酸 | CAS号7757-82-6 元明粉 | CAS号57676-54-7 2-(4-甲基苯基)乙酰肼 | CAS号20834-59-7 2-甲基-1-(对甲苯基)-2-丙醇 | CAS号7398-42-7 4-溴甲基苯乙酸甲酯 | CAS号6529-51-7 4-甲基苯乙基溴 | CAS号699-02-5 2-(4-甲基苯基)乙醇 | CAS号622-47-9 对甲苯乙酸 | CAS号104-09-6 4-甲基苯乙醛 | CAS号18584-20-8 对甲基苯羟乙酸 | CAS号77053-52-2 Benzeneacetic a... | CAS号79443-97-3 Methyl 2-(2-met...

合成工艺路线路线简述

    📜1-(2-溴-1,1-二甲氧基乙基)-4-甲基苯置于silver Tetrafluoroborate体系中,用 甲醇 用作溶剂,化学反应生成对甲苯基乙酸甲酯
    参考文献:Giordano,Claudio; Castaldi,Graziano; Casagrande,Francesco,Journal Of The Chemical Society. Perkin Transactions I,1982,# 11,P. 2575-2582
    标题:Giordano,Claudio; Castaldi,Graziano; Casagrande,Francesco,Journal Of The Chemical Society. Perkin Transactions I,1982,# 11,P. 2575-2582

    海关参考信息

    专利信息


    专利号:WO-2014138989-A1
    优先权日:2013-03-15
    标 题 :Method and intermediates for the synthesis of hydroxamic acid compounds
    发明人:VAISBURG ARKADII; RAEPPEL FRANCK; ROY SIMON; ZHOU NANCY Z
    权利人:METHYLGENE INC
    摘要:Methods are disclosed for making a compound of formula and intermediates therefor, where R is aryl or heteroaryl, and L is C3_8alkylene, wherein each of R, L, and the illustrated phenyl group are independently optionally substituted with one or more substituents selected from the group consisting of C].6alkyl, Ci.6alkoxy, CF3, CHF2, CH2F, fluoro, and cyano, which methods can avoid the use of iodo-phenyl esters, or aryl alkynes, or both, or, in which synthetic methods at least one of the intermediates is a solid at room temperature that does not require purification by chromatography.

    专利号:US-10287225-B2
    优先权日:2015-05-13
    标 题:Chain multiyne compound, preparation method and application thereof
    发明人:XIA HAIPING; ZHUO QINGDE; LIN JIANFENG; ZHOU XIAOXI; CHEN ZHIXIN; SHAO YIFAN; ZHANG HONG; HE XUMIN
    权利人:UNIV XIAMEN
    摘要:The present invention relates to fields of organic chemistry and organometallic chemistry. The present invention discloses a chain multiyne compound, a preparation method thereof and an application in synthesizing a fused-ring metallacyclic compound. A structure of the chain multiyne compound in the present invention is shown as Formula I below. The present invention also provides a preparation method of the chain multiyne compound and an application thereof in a synthesis of a fused-ring metallacyclic compound. The chain multiyne compound disclosed in the present invention has multiple functional groups and the structure of the chain multiyne compound is adjustable. The chain multiyne compound can also be used to synthesize the fused-ring metallacyclic compound efficiently. The preparation method of the chain multiyne compound disclosed in the present invention is simple, which can be used to prepare the chain multiyne compound rapidly and efficiently.

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:An Approach To Spirooxindoles Via Palladium-Catalyzed Remote C-H Activation And Dual Alkylation With Ch2Br2
    作者:Changdong Shao,Zhuo Wu,Xiaoming Ji,Bo Zhou,Yanghui Zhang
    摘要:A Facile And Efficient Approach For The Synthesis Of Spirooxindoles Has Been Developed Via The Coupling Of Spirocyclic C, C-Palladacycles With Ch2Br2. The Key Spirocyclic Palladacycles Are Generated Catalytically Via Intramolecular Remote C-H Activation. A Range Of Spirooxindoles Can Be Synthesized In Good To Excellent Yields From Readily Available Starting Materials.

    合成参考文献


    摘要:Bietti, M.; Dénès, F., Science of Synthesis, (2021) , 542.
    摘要:Bao, Z.; Wang, J., Science of Synthesis: Knowledge Updates, (2023) 2, 22.
    摘要:Kiyokawa, K., Science of Synthesis: Hypervalent Halogens in Organic Synthesis, (2025) .
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