CAS: 19547-38-7; Methyl Picolinimidate

该化合物是一种化学化合物,其特征是其由皮球酸衍生的同质功能组,其典型特征是淡黄色液体无色,以其在有机合成中的试剂作用而著称,特别是在氨化物和酯的形成过程中.该化合物的特征是附于同状物氮的甲基组,增强它的再活性.甲基皮球菌在有机溶剂中可溶解,使其在各种化学反应中有用.它经常用于pitide合成和其他需要选择性细胞化的应用中.在处理该化合物时,应注意安全防范,因为它可能刺激皮肤和眼睛.此外,适当的储存条件对于保持其稳定性和防止降解至关重要.

结构式图片

相似化合物

23579-92-2 2459-07-6 496840-21-2

欧盟法规

ECHA物质C&L通报

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CAS号100-70-9 2-氰基吡啶 | CAS号124-41-4 甲醇钠 | CAS号67-56-1 甲醇 | CAS号51285-26-8 2-脒基吡啶盐酸盐 | CAS号52313-50-5 吡啶-2-甲脒 | CAS号18653-75-3 2-(咪唑-2-基)吡啶 | CAS号7471-05-8 2-(4,5-二氢-1H-咪唑... | CAS号95690-34-9 2-pyridin-2-yl-... | CAS号98390-62-6 N-butyl-2-pyrid... | CAS号56041-30-6 5-pyridin-2-yl-...

合成工艺路线路线简述

  • 合成目标产物 Methyl Picolinimidate 主要起始原料 2-Cyanopyridine And Methanol
  • (文献来源)合成步骤主要原料 2-Cyanopyridine 和 Methanol
📜2-氰基吡啶置于甲醇,Sodium Methylate体系中,化学反应生成甲基吡啶亚胺甲酯
参考文献:五种具有吡啶基/嘧啶基-吡唑衍生的对位配体的氧钒(v)配合物的合成,表征,X射线晶体结构和发射特性
标题:五种具有吡啶基/嘧啶基-吡唑衍生的对位配体的氧钒(v)配合物的合成,表征,X射线晶体结构和发射特性
摘要:杂环基对位配体pypzoap(n-[氨基(吡啶-2-基)亚甲基]-5-甲基-1-(吡啶-2-基)-1 H-吡唑-3-碳酰肼酸的四种氧钒(v)络合物),Pypzoapz(n-[氨基(吡嗪-2-基)亚甲基]-5-甲基-1-(吡啶-2-基)-1 H-吡唑-3-碳酰肼酸),Pympzoap(n-[氨基(吡啶-2-基)亚甲基]-1-(4,6-二甲基嘧啶-2-基)-5-甲基-1 H-吡唑-3-碳酰肼酸)和pypzcap(5-甲基-1-(吡啶-2-Yl)-N '-[1-(吡啶-2-基)亚乙基]-1 H-吡唑-3-碳酰肼)和配体pympzcap的双核(di-μ-Oxo)氧钒(v)络合物(1-(4,6-二甲基嘧啶-2-基)-5-甲基-N研发了'-[1-(吡啶-2-基)亚乙基]-1 H-吡唑-3-碳酰肼).配体充当单负性的vo 2 +离子的单负nno三齿体供体.由于存在诸如1-(2-吡
Doi:10.1016/j.Poly.2011.03.018

海关参考信息

专利信息


专利号:US-2024101506-A1
优先权日:2021-01-26
标 题 :Continuous process for the synthesis of dimethyl carbonate over a cerium-based catalyst formulation
发明人:SRINIVAS DARBHA; BOKADE VIJAY VASANT; NIPHADKAR PRASHANT SURESH; PULIKKEEL UNNIKRISHNAN; PARMAR SNEHALKUMAR; AMTE VINAY; SENGUPTA SURAJIT; DAS ASIT KUMAR
权利人:COUNCIL SCIENT IND RES
摘要:The present invention discloses a continuous process for the synthesis of dimethyl carbonate from methanol and carbon dioxide over a ceria-based mixed metal oxide-silica catalyst formulation in the presence of a dehydrating or water trapping compound (2-Cyanopyridine).

专利号:WO-2025078932-A1
优先权日:2023-10-09
标题 :A process for selective dimethyl carbonate (dmc) synthesis and a system thereof
发明人:PULIKKEEL UNNIKRISHNAN; ROUTRAY KAMALAKANTA; CHINTHALA PRAVEEN KUMAR; DAS ASIT KUMAR
权利人:RELIANCE INDUSTRIES LTD
摘要:The present disclosure provides a process for the selective synthesis of dimethyl carbonate 0 (DMC). More particularly, the present disclosure provides a process for inhibiting catalyst deactivation in a process for selective DMC synthesis. The process is particularly characterized by conducting the process in the presence of a small quantity of air. Further provided herein is a system for facilitating the said process. The process and the system (Figure 1) of the present disclosure prolong the life of the catalyst by virtue of introduction of air into the reactor.

专利号:WO-2025078933-A1
优先权日:2023-10-09
标题 :A process for selective dimethyl carbonate (dmc) synthesis and a system thereof
发明人:PULIKKEEL UNNIKRISHNAN; ROUTRAY KAMALAKANTA; CHINTHALA PRAVEEN KUMAR; DAS ASIT KUMAR; MANDAL SUKUMAR
权利人:RELIANCE INDUSTRIES LTD
摘要:The present disclosure provides a process for the continuous and selective synthesis of Dimethyl carbonate (DMC) addressing issues such as choking, reagent consumption and other downstream issues. The process of the present disclosure is characterized by integration of 2 reactions, one for the conversation of alcohol and carbon dioxide to DMC in the presence of a nitrile based dehydrating agent and the second for the re-generation of the nitrile based dehydrating agent in the presence of a suitable solvent. Further provided herein is a system (Figure 1) for facilitating the said process. The process is characterized by prolonged catalyst activity, efficient regeneration of reactants, low energy requirements and simple regeneration procedures.

专利号:US-5352587-A
优先权日:1989-06-23
标 题:Compositions and methods for the synthesis of natriuretic protein receptor B and methods of use
发明人:CHANG MING-SHI; GOEDDEL DAVID V; LOWE DAVID G
权利人:GENENTECH INC
摘要:PCT No. PCT/US90/03586 Sec. 371 Date Dec. 19, 1991 Sec. 102(e) Date Dec. 19, 1991 PCT Filed Jun. 22, 1990 PCT Pub. No. WO91/00292 PCT Pub. Date Jan. 10, 1991.Described are the amino acid sequence of natriuretic peptide receptor B (NPRB) and DNA encoding NPRB. Also disclosed are expression vectors and cells transformed to express the NPRB, DNA encoding NPRB and diagnostic and therapeutic uses for the NPRB and the DNA encoding NPRB.

专利号:US-8541191-B2
优先权日:2008-08-29
标 题 :Hydrolases, nucleic acids encoding them and methods for biocatalytic synthesis of structured lipids
发明人:DAYTON CHRISTOPHER L G; HITCHMAN TIM; KLINE KATIE; LYON JONATHAN; WALL MARK A; BARTON NELSON R
权利人:DAYTON CHRISTOPHER L G; HITCHMAN TIM; KLINE KATIE; LYON JONATHAN; WALL MARK A; BARTON NELSON R; BUNGE OILS INC
摘要:Provided are hydrolases, including lipases, saturases, palmitases and/or stearatases, and polynucleotides encoding them, and methods of making and using these polynucleotides and polypeptides. Further provided are polypeptides, e.g., enzymes, having a hydrolase activity, e.g., lipases, saturases, palmitases and/or stearatases and methods for preparing low saturate or low trans fat oils, such as low saturate or low trans fat animal or vegetable oils, e.g., soy or canola oils.

专利号:EP-0723402-B1
优先权日:1993-08-30
标 题 :Senescent cell-derived inhibitors of dna synthesis
发明人:SMITH JAMES R
权利人:BAYLOR COLLEGE MEDICINE
摘要:An expression vector cDNA library derived from senescent cells has been used to isolate cDNA clones that encode inhibitors of DNA synthesis. Such inhibitors play a role in cellular senescence, aging and neoplasia. Antisense nucleic acids reduce the inhibition of DNA synthesis. The invention concerns such molecules, their inhibitors, antagonists and derivatives. The invention also concerns diagnostic, therapeutic and in vitro uses for all such agents.

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品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


参考文献:10.1111/j.1432-1033.1972.tb01877.x
摘要:McKinley-McKee JS, Morris DL. The lysines in liver alcohol dehydrogenase. Chemical modification with pyridoxal 5'-phosphate and methyl picolinimidate. Eur J Biochem. 1972 Jun 23;28(1):1–11. doi: 10.1111/j.1432-1033.1972.tb01877.x.
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