CAS: 15442-91-8; 1,2,4,5-Tetrakis(Bromomethyl)Benzene

相似化合物

3095-73-6 91-13-4 21988-87-4

上下游产品

CAS号95-93-2 1,2,4,5-四甲苯 | CAS号35168-62-8 1,4-双(溴甲基)-2,5-二甲苯 | CAS号35117-21-6 triple-layered ... | CAS号1204-76-8 benzene-1,2,4,5... | CAS号14674-89-6 benzene-1,2,4,5... | CAS号70389-19-4 2,6,10,14-tetra... | CAS号82456-99-3 2,4,5-tris(merc... | CAS号64131-86-8 trimethyl-[[2,4... | CAS号54100-59-3 1,2,4,5-[2.2.2....

📜1,4-双(溴甲基)-2,5-二甲苯置于n-溴代丁二酰亚胺(Nbs),过氧化苯甲酰体系中,用 四氯化碳 用作溶剂,化学反应 24.0H,以45%的收率获得四溴甲苯
参考文献:导致哌啶衍生物的级联 Aza-Cope/aza-Prins 环化
标题:导致哌啶衍生物的级联 Aza-Cope/aza-Prins 环化
摘要:已经探索了高烯丙基胺的级联 Aza-Cope/aza-Prins 环化以产生取代的哌啶.由于内部羧酸根阴离子捕获中间阳离子,因此使用乙醛酸作为羰基组分提供双环结构.单分子双-,三-和四(高烯丙胺)有效地提供了附加的双-,三-和四(哌啶-4-醇)(分别为三脚架和十字架形状)作为新实体.后一种化合物在 Suzuki-Miyaura 交叉偶联反应中用作合成肠壳孔蛋白的极好配体.
Doi:10.1002/ejoc.201403607

专利信息

专利号:US-9127123-B2
优先权日:2010-05-27
标 题:Membrane enhanced polymer synthesis
发明人：LIVINGSTON ANDREW GUY; GAFFNEY PIERS ROBERT JAMES; VASCONCELOS RENATO CAMPOS
权利人:LIVINGSTON ANDREW GUY; GAFFNEY PIERS ROBERT JAMES; VASCONCELOS RENATO CAMPOS; IMP INNOVATIONS LTD
摘要:This invention relates to the synthesis of polymers. More specifically, the present invention relates to the synthesis of heterobifunctional polymers and polymers with narrow and mono-disperse molecular weight distributions, and especially to the application of membranes to the synthesis of these polymers.

专利号:US-7189864-B2
优先权日:1990-11-19
标 题:Method of preparing intermediates useful in synthesis of retroviral protease inhibitors
发明人：NG JOHN S; PRZYBYLA CLAIRE A; MUELLER RICHARD A; VAZQUEZ MICHAEL L; GETMAN DANIEL P
权利人:SEARLE & CO
摘要:A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a diastereoselective epoxide from a chiral alpha amino aldehyde.

专利号:US-6022996-A
优先权日:1990-11-19
标 题 :Method for making intermediates useful in synthesis of retroviral protease inhibitors
发明人：NG JOHN S; PRZYBYLA CLAIRE A; MUELLER RICHARD A; VAZQUEZ MICHAEL L; GETMAN DANIEL P
权利人:SEARLE & CO
摘要:A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a diastereoselective epoxide from a chiral alpha amino aldehyde.

专利号:EP-0641333-B1
优先权日:1992-05-20
标 题 :Method for making intermediates useful in synthesis of retroviral protease inhibitors
发明人：NG JOHN S; PRZYBYLA CLAIRE A; MUELLER RICHARD A; VAZQUEZ MICHAEL L; GETMAN DANIEL P
权利人:SEARLE & CO; MONSANTO CO
摘要:A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a diastereoselective epoxide compound of formula (I) from a chiral alpha amino aldehyde and halomethyllithium as an organometallic methylene-adding reagent. In formula (I) R<1> is selected from alkyl, aryl, cycloalkyl, cycloalkylalkyl and arylalkyl, which are optionally substituted with a group selected from alkyl, halogen, NO2, OR<9> or SR<9>, where R<9> represents hydrogen or alkyl; and P<1> and P<2> independently are selected from amine protecting groups, including but not limited to, arylalkyl, substituted arylalkyl, cycloalkenylalkyl and substituted cycloalkenylalkyl, allyl, substituted allyl, acyl, alkoxycarbonyl, aralkoxycarbonyl and silyl.

专利号:EP-0855388-B1
优先权日:1993-11-23
标 题 :Method for making intermediates useful in synthesis of retroviral protease inhibitors
发明人：NG JOHN S; PRZYBYLA CLAIRE A; MUELLER RICHARD A; VAZQUEZ MICHAEL L; GETMAN DANIEL P; FRESKOS JOHN J; DECRESCENZO GARY A; BERTENSHAW DEBORAH E; HEINTZ ROBERT M; ZHANG SUHONG; LIU CHIN; LANEMAN SCOTT A
权利人:SEARLE & CO
摘要:A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a cyanohydrin from a chiral alpha amino aldehyde.

专利号:US-2002161234-A1
优先权日:1990-11-19
标 题 :Method of preparing intermediates useful in synthesis of retroviral protease inhibitors