CAS: 15351-09-4; 2-(Dimethylamino)-1-Phenylpropan-1-One

该化合物其结构特征为附于丙酮骨干的一个苯基组,该化合物具有合成有机化学的特性,因为它作为制药,农用化学品和特殊化学品的生产中间体的潜力.二甲基氨基组可增强反应性,促进核生殖或电生殖性转变.其定义明确的分子结构允许精确的修改,使其在需要控制功能化的研究和工业应用中具有价值.该化合物在标准条件下的稳定性确保合成工艺的一贯性.进一步的研究可能会探索其在非对称合成或作为生物活性分子的前体的用途.

结构式图片

欧盟法规

ECHA物质ECHA物质化妆品禁用物质清单C&L通报REACH预注册

上下游产品

卡西酮 (+/-)-Cathinone 5265-18-9
苯丙酮 1-Phenyl-Propan-1-One 93-55-0

合成工艺路线路线简述

    📜卡西酮置于聚合甲醛,甲酸,Sodium Acetate体系中,化学反应生成甲胺苯丙酮
    参考文献:Sugasawa Et Al.,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1951,Vol. 71,P. 530
    标题:Sugasawa Et Al.,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1951,Vol. 71,P. 530

    海关参考信息

    专利信息


    专利号:US-11717498-B2
    优先权日:2013-12-31
    标题 :Methods of treatment using amphetamine controlled release, prodrug, and abuse deterrent dosage forms
    发明人:POPP KARL; MECKLER HAROLD
    权利人:Chemapotheca LLC; PHARMAPOTHECA A INC
    摘要:The invention also relates to pharmaceutical compositions comprising highly pure amphetamine and amphetamine-class compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds, and to methods of manufacturing, delivering, and using the amphetamine compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds.

    专利号:US-8598153-B2
    优先权日:2006-09-22
    标题 :Method of treatment using fatty acid synthesis inhibitors
    发明人:SINGH SHEO B; TOTA MICHAEL R; WANG JUN
    权利人:SINGH SHEO B; TOTA MICHAEL R; WANG JUN; MERCK SHARP & DOHME
    摘要:The present invention relates to natural products that possess fatty acid synthesis inhibitor activity and can be used to treat and prevent diseases such as obesity, cancer, diabetes, fungal infections, Mycobacterium tuberculosis infections, malarial infections and other apicomplexan protozoal diseases.

    专利号:US-5510375-A
    优先权日:1993-11-19
    标 题 :Coumarin derivatives as protease inhibitors and antiviral agents
    发明人:DOMAGALA JOHN M; HAGEN SUSAN E; LUNNEY ELIZABETH; TAIT BRADLEY D
    权利人:WARNER LAMBERT CO
    摘要:The present invention relates to novel coumarin derivatives and related compounds which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The coumarin derivatives are useful in the development of therapies for the treatment of viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized coumarins and of related structures.

    专利号:WO-2008062473-A1
    优先权日:2006-10-31
    标 题 :Process for preparing atomoxetine hydrochloride
    发明人:PATEL VIPUL KANTIBHAI; KUMAR RAJIV; DHAR DWIVEDI SHRIPRAKASH
    权利人:CADILA HEALTHCARE LTD; PATEL VIPUL KANTIBHAI; KUMAR RAJIV; DHAR DWIVEDI SHRIPRAKASH
    摘要:The present invention relates to the process for preparing Atomoxetine hydrochloride which is a selective norepinephrine reuptake inhibitor. Atomoxetine HCl is chemically known as (-)-iV-Methyl-3-phenyl-3-(o-tolyloxy)-propylamine hydrochloride and represented by formula (I). More particularly, the invention relates to crystalline form of N-methyl-3-phenyl-3-(o- tolyloxy) propylamine oxalate (here in after referred as '(±) Atomoxetine Oxalate'), which is an useful intermediate for the synthesis of Atomoxetine hydrochloride.

    专利号:AU-2007300627-A1
    优先权日:2006-09-22
    标题:Method of treatment using fatty acid synthesis inhibitors

    专利号:AU-2007300627-B2
    优先权日:2006-09-22
    标题 :Method of treatment using fatty acid synthesis inhibitors

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Xie, J.-H.; Zhou, Q.-L., Science of Synthesis, (2022) , 404.
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