📜卡西酮置于聚合甲醛,甲酸,Sodium Acetate体系中,化学反应生成甲胺苯丙酮 参考文献:Sugasawa Et Al.,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1951,Vol. 71,P. 530 标题:Sugasawa Et Al.,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1951,Vol. 71,P. 530
专利号:US-11717498-B2 优先权日:2013-12-31 标题 :Methods of treatment using amphetamine controlled release, prodrug, and abuse deterrent dosage forms 发明人:POPP KARL; MECKLER HAROLD 权利人:Chemapotheca LLC; PHARMAPOTHECA A INC 摘要:The invention also relates to pharmaceutical compositions comprising highly pure amphetamine and amphetamine-class compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds, and to methods of manufacturing, delivering, and using the amphetamine compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds.
专利号:US-8598153-B2 优先权日:2006-09-22 标题 :Method of treatment using fatty acid synthesis inhibitors 发明人:SINGH SHEO B; TOTA MICHAEL R; WANG JUN 权利人:SINGH SHEO B; TOTA MICHAEL R; WANG JUN; MERCK SHARP & DOHME 摘要:The present invention relates to natural products that possess fatty acid synthesis inhibitor activity and can be used to treat and prevent diseases such as obesity, cancer, diabetes, fungal infections, Mycobacterium tuberculosis infections, malarial infections and other apicomplexan protozoal diseases.
专利号:US-5510375-A 优先权日:1993-11-19 标 题 :Coumarin derivatives as protease inhibitors and antiviral agents 发明人:DOMAGALA JOHN M; HAGEN SUSAN E; LUNNEY ELIZABETH; TAIT BRADLEY D 权利人:WARNER LAMBERT CO 摘要:The present invention relates to novel coumarin derivatives and related compounds which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The coumarin derivatives are useful in the development of therapies for the treatment of viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized coumarins and of related structures.
专利号:WO-2008062473-A1 优先权日:2006-10-31 标 题 :Process for preparing atomoxetine hydrochloride 发明人:PATEL VIPUL KANTIBHAI; KUMAR RAJIV; DHAR DWIVEDI SHRIPRAKASH 权利人:CADILA HEALTHCARE LTD; PATEL VIPUL KANTIBHAI; KUMAR RAJIV; DHAR DWIVEDI SHRIPRAKASH 摘要:The present invention relates to the process for preparing Atomoxetine hydrochloride which is a selective norepinephrine reuptake inhibitor. Atomoxetine HCl is chemically known as (-)-iV-Methyl-3-phenyl-3-(o-tolyloxy)-propylamine hydrochloride and represented by formula (I). More particularly, the invention relates to crystalline form of N-methyl-3-phenyl-3-(o- tolyloxy) propylamine oxalate (here in after referred as '(±) Atomoxetine Oxalate'), which is an useful intermediate for the synthesis of Atomoxetine hydrochloride.
专利号:AU-2007300627-A1 优先权日:2006-09-22 标题:Method of treatment using fatty acid synthesis inhibitors
专利号:AU-2007300627-B2 优先权日:2006-09-22 标题 :Method of treatment using fatty acid synthesis inhibitors