CAS: 10605-21-7; Carbendazim

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6306-71-4 65003-40-9 77474-99-8

专利信息

专利号:US-9266902-B2
优先权日:2008-07-29
标题:Labelling reagents having a pyridine nucleus bearing a diazomethyl function, process for synthesis of such reagents and processes for detection of biological molecules
发明人：LAURENT ALAIN; LAAYOUN ALI; KOTERA MITSUHARA
权利人:LAURENT ALAIN; LAAYOUN ALI; KOTERA MITSUHARA; BIOMERIEUX SA; UNIV STRASBOURG; CENTRE NAT RECH SCIENT
摘要:A process for synthesis of a labelling reagent, a process for the labelling of a biological molecule, a labelled biological molecule obtained by the process, a process for labelling and fragmentation of a single or double strand nucleic acid, a labelled nucleic acid capable of being obtained by the process, a kit for detection of a target nucleic acid containing a labelled nucleic acid, a solid support onto which is attached a reagent and a process for capture of nucleic acids.

专利号:EP-1383732-B1
优先权日:2001-05-04
标题:Labelling reagents, method for synthesis of said reagents and methods for detecting biological molecules
发明人：BOURGET CECILE; LHOMME JEAN; LAAYOUN ALI; KOTERA MITSUHARU; TREVISIOL EMMANUELLE; MENOU LIONEL; BERNAL MENDEZ ELOY
权利人:BIO MERIEUX; UNIV GRENOBLE 1; CENTRE NAT RECH SCIENT
摘要:The invention concerns a temperature-stable labelling reagent of formula (I), wherein: R<1> represents H or an alkyl, aryl or substituted aryl group; R<2> represents a detectable marker or at least two detectable markers linked together by at least a multimeric structure; L is a linking arm comprising a linear catemer concatenation of at least two covalent bonds; and n is an integer equal to 0 or 1; R<3> and R<4> represent, independently of each other: H, NO2, Cl, Br, F, I, R<2>-(L)n-Y-X-, OR, SR, NR2, R, NHCOR, CONHR, COOR with R = alkyl or aryl, A is a linking arm comprising at least a double bond enabling the conjugation of the diazo function with the aromatic cycle; and u is a whole number between 0 and 2, preferably between 0 and 1; and -Y-X- represents -CONH-, -NHCO-, -CH2O-, -CH2S-. The invention also concerns a method for the synthesis of said markers and uses for labelling biological molecules, in particular nucleic acids, with a labelling reagent bearing the diazomethyl function. The invention is particularly applicable in the field of diagnosis.

专利号:US-8772526-B2
优先权日:2009-12-21
标 题:Method for preparing dithiocarbamates in particular from polyols of the glycerol type
发明人：JEROME FRANCOIS; DE SOUSA RODOLPHE; BARRAULT JOEL; POUILLOUX YANNICK
权利人:JEROME FRANCOIS; DE SOUSA RODOLPHE; BARRAULT JOEL; POUILLOUX YANNICK; CENTRE NAT RECH SCIENT; UNIV POITIERS
摘要:The present invention concerns a method for the synthesis of glycerol dithiocarbamates or bis-dithiocarbamates (GDTCs) in which a reaction medium comprising (1) a carbonate selected from diethyl carbonate, dimethyl carbonate and ethylene or propylene carbonate associated with a glycerol type polyol in the presence of a basic catalyst or (2) a cyclic carbonate comprising five ring members, in a solvent medium, is supplemented with a primary or secondary amine in the presence of carbon disulphide, and the GDTC formed is recovered. In particular, a glycerol type polyol is brought into the presence of diethyl carbonate in the presence of a catalyst, then a primary or secondary amine is added to the reaction medium in the presence of carbon disulphide, and the GDTC formed is recovered. The invention can be used for one-step synthesis of glycerol dithiocarbamates directly from glycerol as the starting material and solvent. This method involves glycerol, diethyl carbonate, carbon disulphide (CS 2 ) and a primary or secondary amine to produce glycerol dithiocarbamates; the glycerol/NaOH phase can be recycled 6 times without a noticeable drop in yield; the ethyl acetate is also recycled after each extraction.

专利号:WO-2020130862-A1
优先权日:2018-12-17
标题:Lyophilized fertilizer composition comprising iron siderophore chelates, lyophilized composition comprising siderophores, their processes of obtention and uses to treat plants
发明人：MONTEIRO SOARES HELENA MARIA VIEIRA; HENRIQUES FERREIRA CARLOS MIGUEL; VALENTE SOARES EDUARDO JORGE; LUCENA MAROTTA JUAN JOSÉ; LOPÉZ RAYO SANDRA
权利人:UNIV DO PORTO; INST SUPERIOR DE ENGENHARIA DO PORTO; UNIV MADRID AUTONOMA
摘要:Lyophilized fertilizer composition comprising iron siderophore chelates and a stabilizing agent and a lyophilized composition comprising siderophores and a stabilizing agent, wherein the stabilizing agent is starch. The invention further relates to processes of obtaining a lyophilized fertilizer composition and a lyophilized composition comprising a step of synthesis of at least one siderophore compound by means of biochemical transformation performed by at least one microorganism, and to the use of the compositions for treating cultivated plants, for example in conditions of low iron availability, wherein the compositions are capable of correcting chlorosis in plants and do not present environmental risks. The lyophilized fertilizer composition and the lyophilized composition have high storage stability.

专利号:US-8309695-B2
优先权日:2007-06-11
标题 :Marking reagents bearing diazo and nitro functions, methods for the synthesis of such reagents and methods for detecting biological molecules
发明人：LAURENT ALAIN; LAAYOUN ALI; KOTERA MITSUHARU
权利人:LAURENT ALAIN; LAAYOUN ALI; KOTERA MITSUHARU; BIOMERIEUX SA; CENTRE NAT RECH SCIENT; UNIV STRASBOURG
摘要:The present invention relates to a labeling reagent of formula: n nin which:n R 1 represents at least one detectable label, L and A are each a linker arm, n is an integer equal to 1, and u is an integer between 0 and 2.n nThe present invention also describes a method of synthesizing said markers and also applications for the labeling of biological molecules, more particularly nucleic acids, with a labeling reagent bearing diazo and nitro functions. The invention is particularly suitable for use in the diagnostics field.

专利号:WO-2025056767-A1
优先权日:2023-09-15
标题 :Process for the preparation of enantiomerically enriched aliphatic amines
发明人：BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
权利人:SYNGENTA CROP PROTECTION AG
摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.