CAS: 95-00-1; (2,4-Dichlorophenyl)Methanamine

• 英文名称(2,4-Dichlorophenyl)Methanamine
• 中文名称2,4-二氯苯甲胺
• IUPAC名称(2,4-dichlorophenyl)methanamine
• 其它别名2,4-二氯苄胺; Nsc 25064; 2,4-Dichlorobenzylamine
• CAS编号95-00-1
• MFCD编号:MFCD00008109
• EINECS号:202-382-6
• FDA UNII编号:TL3J7NC8YC
• 分子式:C7H7Cl2N
• 分子量:176.04
• 产品CID: 2002378
• 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

• 相似结构搜索
• 产品信息参考;
• InChIKey: SJUKJZSTBBSGHF-UHFFFAOYSA-N
• InChI=1S/C7H7Cl2N/c8-6-2-1-5(4-10)7(9)3-6/h1-3H,4,10H2…
• 计算化学: 氢键受体数1.0氢键供体数1.0可旋转键数1.0

物理性质

• 熔点309-311 °C
• 沸点221.6°C at 760 mmHg
• 闪点110°C
• 密度1.3±0.1 g/cm3
• pKa:8.31±0.10(预测)
• PSA:26.02
• LogP:2.4521
• 折射率1.582
• 蒸汽压0.1±0.4 mmHg at 25°C
• 敏感性空气敏感
• 外观形态透明无色液体
• 储存条件在惰性气体(氮气或氩气)下 2–8 °C

MSDS等安全信息

• GHS象形图
• GHS符号GHS05;
  注释: Corrosion
• 危险类别皮肤腐蚀 类别1B
  严重眼损伤 类别1
  皮肤腐蚀 类别1C
• 警示词Danger(危险)
• 危险描述H314 |造成严重皮肤灼伤和眼损伤.
  H318 |造成严重眼损伤.
• 防范说明P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
• 危险等级8
• UN编号2735.0
• 危险品标志C,Xi
• 包装等级Ⅲ
• 安全声明26-36/37/39-45-24/25-23
• 危险类别码34-36/37/38
• WGK Germany3

欧盟法规

上下游产品

合成工艺路线路线简述

• 6574-98-7 = 95-00-1
  反应条件:1.1 Reagents: N,N-Bis(1-Methylethyl)Boranamine Catalysts: Lithium Borohydride Solvents: Tetrahydrofuran; 5 H,25 °C; 25 °C -> 0 °C1.2 Reagents: Hydrochloric Acid Solvents: Water; 30 Min,Acidified,0 °C1.3 Reagents: Sodium Hydroxide; Ph 10,0 °C
  标题:Reductions Of Aliphatic And Aromatic Nitriles To Primary Amines With Diisopropylaminoborane
  作者:Haddenham,Dustin; Pasumansky,Lubov; Desoto,Jamie; Eagon,Scott; Singaram,Bakthan
  参考文献:Journal Of Organic Chemistry 日期:2009 卷标:74(5) 页码:1964-1970]
  
  56843-28-8 = 95-00-1
  反应条件:1.1 Catalysts: Iron Oxide (Fe3O4),Zirconium Chloride (Zrcl4); Rt -> 80 °C1.2 Reagents: Sodium Cyanoborohydride; 75 - 80 °C; 50 Min,75 - 80 °C
  标题:The Efficient Solvent-Free Reduction Of Oximes To Amines With Nabh3Cn Catalyzed By Zrcl4/nano Fe3O4 System
  作者:Sadighnia,Leila; Zeynizadeh,Behzad
  参考文献:Journal Of The Iranian Chemical Society 日期:2015 卷标:12(5) 页码:873-878]
  
  94-99-5 = 95-00-1
  反应条件:1.1 Reagents: Sodium Amide Catalysts: Choline Chloride; 30 Min,100 °C; 100 °C -> 60 °C1.2 Overnight,60 °C
  标题:Solvent-Free Choline Derivative Synthesis As A Powerful Organic Synthesis Medium
  作者:Kamali,Ehsan; Mohammadkhani,Abolfazl; Pazoki,Farzane; Heydari,Akbar
  参考文献:Chemistryselect 日期:2023 卷标:8(10)]
  
  6574-98-7 = 95-00-1
  反应条件:1.1 Reagents: Nickel Dichloride,Sodium Borohydride Solvents: Ethanol
  标题:Rapid Reduction Of Nitriles To Primary Amines With Nickel Boride At Ambient Temperature
  作者:Khurana,Jitender M.; Kukreja,Gagan
  参考文献:Synthetic Communications 日期:2002 卷标:32(8) 页码:1265-1269]
  
  74805-30-4 = 95-00-1
  反应条件:1.1 Reagents: Triphenylphosphine Solvents: Tetrahydrofuran,Water; 0 °C; 16 H,25 - 30 °C
  标题:Preparation Of Muscarinic M1 Receptor Positive Allosteric Modulators
  参考文献:India]
  
  = 95-00-1 [标题:Reaction Conditions
  标题:Neuropharmacological Investigation Of N-Benzylsulfamides
  作者:Aeberli,Paul; Gogerty,John; Houlihan,William J.
  参考文献:Journal Of Medicinal Chemistry 日期:1967 卷标:10(4) 页码:636-42]
  
  874-42-0 = 95-00-1
  反应条件:1.1 Reagents: Hydrogen,Ammonium Hydroxide Catalysts: Nickel (Silica-Supported Iron Oxide) Solvents: Ethanol; 20 Bar,Rt; 2 H,20 Bar,115 °C
  标题:Microwave-Assisted Reductive Amination With Aqueous Ammonia: Sustainable Pathway Using Recyclable Magnetic Nickel-Based Nanocatalyst
  作者:Manzoli,Maela; Gaudino,Emanuela Calcio; Cravotto,Giancarlo; Tabasso,Silvia; Baig,R. B. Nasir; Et Al
  参考文献:Acs Sustainable Chemistry & Engineering 日期:2019 卷标:7(6) 页码:5963-5974]
  
  6574-98-7 = 95-00-1
  反应条件:1.1 Reagents: Sodium Borohydride Catalysts: Nickel (Nanoparticle On Silanized Magnetite Microgel) Solvents: Water; 2 H,Ph 5.5,25 °C
  标题:Fe3O4-Sio2-P4Vp Ph-Sensitive Microgel For Immobilization Of Nickel Nanoparticles: An Efficient Heterogeneous Catalyst For Nitrile Reduction In Water
  作者:Nabid,Mohammad Reza; Bide,Yasamin; Niknezhad,Mahvash
  参考文献:Chemcatchem 日期:2014 卷标:6(2) 页码:538-546]
  
  56843-28-8 = 95-00-1
  反应条件:1.1 Reagents: Alumina,Zirconium Chloride (Zrcl4)1.2 > 1 Min,Rt1.3 Reagents: Sodium Borohydride; 2 Min,Rt
  标题:A Rapid And Practical Protocol For Solvent-Free Reduction Of Oximes To Amines With Nabh4/zrcl4/al2O3 System
  作者:Zeynizadeh,Behzad; Kouhkan,Mehri
  参考文献:Bulletin Of The Korean Chemical Society 日期:2011 卷标:32(9) 页码:3448-3452]
  
  56843-28-8 = 95-00-1
  反应条件:1.1 Reagents: Acetic Acid,Zinc; 0.7 H,Rt
  标题:The Efficient Reduction Of Oximes To Amines With Zn And Acetic Acid Under Ultrasonic Irradiation
  作者:Cao,Yu-Qing; Liu,Rui-Yan; Qu,An-Li; Jin,Yuan-Yuan
  参考文献:Organic Chemistry: An Indian Journal 日期:2009 卷标:5(4) 页码:412-415]
  
  56843-28-8 = 95-00-1
  反应条件:1.1 Reagents: (Sp-5-12)-(Pyridine)Bis[tetrahydroborato(1-)-Kh,Kh′]Zinc Solvents: Tetrahydrofuran; 4 H,Reflux
  标题:First Report For The Efficient Reduction Of Oximes To Amines With Zinc Borohydride In The Form Of (Pyridine)(Tetrahydroborato)Zinc Complex
  作者:Zeynizadeh,Behzad; Zahmatkesh,Karam
  参考文献:Journal Of The Chinese Chemical Society (Taipei 日期:2005 卷标:52(1) 页码:109-112]
  
  6574-98-7 = 95-00-1
  反应条件:1.1 Reagents: Sodium Borohydride Catalysts: Copper Solvents: Water; 4 H,35 °C
  标题:Synthesis And Characterization Of Copper Nanoparticles On Walnut Shell For Catalytic Reduction And C-C Coupling Reaction
  作者:Zamani,Asghar; Poursattar Marjani,Ahmad; Nikoo,Abbas; Heidarpour,Mojtaba; Dehghan,Ahmad
  参考文献:Inorganic And Nano-Metal Chemistry 日期:2018 卷标:48(3) 页码:176-181]
  
  108013-05-4 = 95-00-1 [标题:Reaction Conditions
  标题:Monoamine Oxidase Inhibitors Based On 2-,4-,And 8-Substituted Quinolines
  作者:Gracheva,I. N.; Ioffina,D. I.; Tochilkin,A. I.; Gorkin,V. Z.
  参考文献:Khimiko-Farmatsevticheskii Zhurnal 日期:1991 卷标:25(3) 页码:18-21]
  
  6574-98-7 = 95-00-1
  反应条件:1.1 Reagents: Sodium Borohydride Catalysts: Copper Iron Oxide (Cufe2O4) Solvents: Water; 15 Min,Reflux
  标题:Green And Convenient Protocols For The Efficient Reduction Of Nitriles And Nitro Compounds To Corresponding Amines With Nabh4 In Water Catalyzed By Magnetically Retrievable Cufe2O4 Nanoparticles
  作者:Zeynizadeh,Behzad; Mohammad Aminzadeh,Farkhondeh; Mousavi,Hossein
  参考文献:Research On Chemical Intermediates 日期:2019 卷标:45(6) 页码:3329-3357]
  
  6574-98-7 = 95-00-1
  反应条件:1.1 Reagents: Hydrogen,Ammonia Catalysts: Nickel Solvents: Isopropanol,Water; 10 - 12 H,10 Kg/cm2,60 - 80 °C
  标题:Process For Preparation Of Halogenated Benzylamines By Selective Dehalogenation Of Halogenated Benzonitriles And Hydrogenation
  参考文献:India]
  
  = 95-00-1 [标题:Reaction Conditions
  标题:Benzylamines: Synthesis And Evaluation Of Antimycobacterial Properties
  作者:Meindl,Wolfgang R.; Von Angerer,Erwin; Schoenenberger,Helmut; Ruckdeschel,Gotthard
  参考文献:Journal Of Medicinal Chemistry 日期:1984 卷标:27(9) 页码:1111-18

海关参考信息

• 2902300000-甲苯
  2903919090-氯苯
  2903991000-对氯甲苯
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

专利信息

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• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管