CAS: 705-79-3; 3-Chloro-4-Fluorophenylacetic Acid

上下游产品

CAS号348-51-6 2-氯氟苯 | CAS号2994-69-6 3-氯-4-氟苄氯 | CAS号658-98-0 3-氯-4-氟苯乙腈 | CAS号2923-66-2 3'-氯-4'-氟苯乙酮

3-氯-4-氟苯乙腈置于硫酸,溶剂黄146体系中,化学反应生成 3-氯-4-氟苯乙酸
参考文献:2,4-Diamino-5-[4'-Fluoro-3'-Halogenophenyl]Pyrimidines
标题:2,4-Diamino-5-[4'-Fluoro-3'-Halogenophenyl]Pyrimidines
摘要:
DOI:10.1021/jo01351A050

专利信息

专利号:US-2025091989-A1
优先权日:2023-09-19
标 题 :Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.