CAS: 64421-28-9; Methyl (1S,4As,5R,7S,7As)-5,7-Dihydroxy-7-Methyl-1-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)-1,4A,5,6,7,7A-Hexahydrocyclopenta[c]Pyran-4-Carboxylate
该化合物是一种晶体物质,有助于其溶性与生物活动;多种氢基体组的存在表明氢联结的潜力,增强其再活性和与生物系统的相互作用;六氢环球结构表明一种结合环系系统,可能影响其一致性稳定性和总体分子几何测量;该化合物可能具有各种药性特性,有可能作为药化学应用的天然产品;其具体的立体化学对其生物活动至关重要,因为功能组的取方向可能显著影响生物目标中的天然化合物.
- 英文名称Methyl (1S,4As,5R,7S,7As)-5,7-Dihydroxy-7-Methyl-1-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)-1,4A,5,6,7,7A-Hexahydrocyclopenta[c]Pyran-4-Carboxylate
- 中文名称山栀苷甲酯
- IUPAC名称methyl (1S,4aS,5R,7S,7aS)-5,7-dihydroxy-7-methyl-1-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate
- 其它别名Methyl (1S,5R,7S)-5,7-Dihydroxy-7-Methyl-1-[(2R,3S,4R,5R,6S)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxy-4A,5,6,7A-Tetrahydro-1H-Cyclopenta[c]Pyran-4-Carboxylate
- CAS编号64421-28-9
- MFCD编号:MFCD00017416
- 分子式:C17H26O11分子量:406.38
- 产品CID: 1628366
- 产品分类天然产物 → 环烯醚萜衍生物
物理性质
MSDS等安全信息
上下游产品
diazomethane 6-O-syringyl-8-O-acetyl shanzhiside methyl ester barlerin(1S,4aS,5R,7S,7aS)-5,7-Dihydroxy-7-methyl-1-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-trityloxymethyl-tetrahydro-pyran-2-yloxy)-1,4a,5,6,7,7a-hexahydro-cyclopenta[c]pyran-4-carboxylic acid methyl ester合成工艺路线路线简述
📜8-O-乙酰山栀苷甲酯(标准品)置于potassium Carbonate体系中,用60 Mg的收率获得产物三栀子甙甲酯
参考文献:Nicoletti,Marcello; Chapya,Wycliffe Andrew; Messana,Irene,Gazzetta Chimica Italiana,1984,Vol. 114,# 1/2,P. 49-54
标题:Nicoletti,Marcello; Chapya,Wycliffe Andrew; Messana,Irene,Gazzetta Chimica Italiana,1984,Vol. 114,# 1/2,P. 49-54
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Xia MY, Wang Y, Zheng YH, Song YN, Liu TL, Zhang C. [Quality changes of Gardeniae Fructus Praeparatus processed by different frying methods: a color- component correlation analysis]. Zhongguo Zhong Yao Za Zhi. 2021 May;46(9):2197-2206. Chinese. doi: 10.19540/j.cnki.cjcmm.20210220.303. 6(6):4495-4505. doi: 10.1021/acsomega.0c06201.
3: Zhao X, Jiang S, Dong Q, Dang J, Liu Z, Han H, Tao Y, Yue H. Anti-rheumatoid arthritis effects of iridoid glucosides from Lamiophlomis rotata (Benth.) kudo on adjuvant-induced arthritis in rats by OPG/RANKL/NF-κB signaling pathways. J Ethnopharmacol. 2021 Feb 10;266:113402. doi: 10.1016/j.jep.2020.113402. Epub 2020 Sep 24.
249:112374. doi: 10.1016/j.jep.2019.112374. Epub 2019 Nov 5. 74(11-12):289-293. doi: 10.1515/znc-2019-0113. 42(10):1886-1895. doi: 10.1002/jssc.201801354. Epub 2019 Mar 19.
合成参考文献
参考文献:10.1515/znc-2000-3-402
摘要:Alipieva KI, Jensen SR, Franzyk H, Handjieva NV, Evstatieva LN. Iridoid glucosides from Phlomis tuberosa L. and Phlomis herba-ventis L. Z Naturforsch C J Biosci. 2000 Mar;55(3-4):137–40. doi: 10.1515/znc-2000-3-402.
参考文献:10.1002/pca.2557
摘要:Pan Z, Fan G, Yang R, Luo W, Zhou X, Zhang Y. Discriminating Lamiophlomis rotata According to Geographical Origin by 1 H‐NMR Spectroscopy and Multivariate Analysis. Phytochemical Analysis. 2015 Feb 19;26(4):247–52. doi: 10.1002/pca.2557.
📝 需求与反馈
尽可能描述清楚需求与问题信息
