CAS: 33375-06-3; (R)-(+)-1-Phenylethylisocyanate

相似化合物

14649-03-7 3173-56-6 3634-83-1

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CAS号75-44-5 光气 | CAS号3886-69-9 R(+)-alpha-甲基苄胺 | CAS号503-38-8 氯甲酸三氯甲酯 | CAS号82826-58-2 (R)-N-hydroxy-2... | CAS号24424-95-1 bis[(2-methylpr... | CAS号32315-10-9 三光气 | CAS号3886-69-9 R(+)-alpha-甲基苄胺

(2R)-N-Hydroxy-2-Phenylpropanamide置于carbonyldiimidazole体系中,用 乙腈 用作溶剂,化学反应 0.5H,反应生成(R)-(+)-1-苯乙基异氰酸酯
参考文献:羰基二咪唑介导的丢失重排
标题:羰基二咪唑介导的丢失重排
摘要:发现羰基二咪唑(cdi)介导各种异羟肟酸的洛森重排为异氰酸酯.该过程在实验上是简单且温和的,咪唑和co 2是唯一的化学计量副产物.对于大规模应用而言意义重大,该方法避免了使用有害试剂,因此是curtius和hofmann重排标准处理条件的绿色替代方案.
Doi:10.1021/ol9023387

专利信息

专利号:US-4108870-A
优先权日:1977-06-06
标 题:Stereocontrolled synthesis of α-multistriatin
发明人：FRIED JOSEF; ELLIOTT WILLIAM J
权利人:UNIV CHICAGO
摘要:A practical stereocontrolled synthesis of a mixture containing a major amount of α-multistriatin and a minor amount of γ-multistriatin in an overall yield of about 73% from cis-2-butene-1,4-diol is provided. α-Multistriatin is one of the three essential components of the aggregation pheromone of the European elm bark beetle.

专利号:US-6175009-B1
优先权日:1999-11-18
标题:Process for the preparation of quinazolinones
发明人：CONFALONE PASQUALE NICHOLAS; MAGNUS NICHOLAS ANDREW; STORACE LOUIS
权利人:DU PONT PHARM CO
摘要:The present invention relates generally to an asymmetric synthesis of 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolinones, and intermediates thereof. The target compounds are useful for the treatment of human immunodeficiency virus (HIV) as an inhibitor of reverse transcriptase.

专利号:US-2009281176-A1
优先权日:2007-11-01
标题:Process for the synthesis of ramelteon and its intermediates
发明人：KANSAL VINOD KUMAR; MISTRY DHIRENKUMAR N; VASOYA SANJAY L; PATEL RAKESH; JADAV ARPAN M
权利人:KANSAL VINOD KUMAR; MISTRY DHIRENKUMAR N; VASOYA SANJAY L; PATEL RAKESH; JADAV ARPAN M
摘要:A process for the preparation of ramelteon and intermediates useful in the process. The process suitable for industrial scale provides increased yield and/or greater purity with fewer process steps.

专利号:WO-0029391-A1
优先权日:1998-11-19
标题 :Process for the preparation of quinazolinones
发明人：CONFALONE PASQUALE NICHOLAS; MAGNUS NICHOLAS ANDREW; STORACE LOUIS
权利人:DU PONT PHARM CO
摘要:The present invention relates generally to an asymmetric synthesis of 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolinones, and intermediates thereof. The target compounds are useful for the treatment of human immunodeficiency virus (HIV) as an inhibitor of reverse transcriptase.

专利号:WO-2009056993-A2
优先权日:2007-11-01
标题 :A process for the synthesis of ramelteon and its intermediates

专利号:US-2010120031-A1
优先权日:2006-09-22
标题 :Synthesis of trans-tert-butyl-2-aminocyclopentylcarbamate