CAS: 31928-44-6; 2-Bromo-4-Chloro-1-Iodobenzene

上下游产品

CAS号873-38-1 2-溴-4-氯苯胺 | CAS号637-87-6 对氯碘苯 | CAS号106-47-8 对氯苯胺 | CAS号50-53-3 氯丙嗪 | CAS号71095-42-6 5-氯-3-甲基-1H-吲哚 | CAS号819871-68-6 4-chloro-1-ethy...

2-溴-4-氯苯胺置于n-碘代丁二酰亚胺,Sodium Nitrite体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应 4.0H,以78%的收率获得2-溴-4-氯-1-碘苯
参考文献:通过亚硝酸钠和n-卤代琥珀酰亚胺将芳胺直接转化为卤代芳烃
标题:通过亚硝酸钠和n-卤代琥珀酰亚胺将芳胺直接转化为卤代芳烃
摘要:描述了一种在室温下在无金属和无酸条件下,通过与亚硝酸钠(nano 2)和n-卤代琥珀酰亚胺(nxs)在dmf中反应,将芳基胺转化为芳基卤化物的一锅通用方法.建议与桑德迈尔反应互补的这一新方案涉及原位产生的硝基卤化物引起芳基胺的亚硝化反应,形成重氮中间体,将其卤化以提供芳基卤化物.
Doi:10.1002/chem.201803347

专利信息

专利号:EP-0977739-B1
优先权日:1997-03-25
标题 :Synthesis of intermediates useful in preparing tricyclic compounds
发明人：CHEN XING; POIRIER MARC; WONG YEE-SHING; WU GUANG-ZHONG
权利人:SCHERING CORP
摘要:The invention relates to a process for preparing a compound of formula (I), comprising reacting a bromo-substituted pyridine with an amine of the formula NHR5R6, reacting the resulting amide with an iodo-halomethyl-substituted compound and cyclizing the resultant product, wherein R, R?1, R2, R3 and R4¿ are as defined in the specification; also claimed are a compound of formula (a), and a process for preparing it from the corresponding halo-substituted benzoic acid.

专利号:EP-0977739-A1
优先权日:1997-03-25
标题 :Synthesis of intermediates useful in preparing tricyclic compounds

专利号:CN-108395424-A
优先权日:2018-02-08
标 题:A method for the synthesis of benzothiophene derivatives from copper-catalyzed dihalogenated arenes under microwave radiation

专利号:CN-104892539-A
优先权日:2015-05-29
标题 :A new method for the synthesis of 2-arylbenzoxazole compounds catalyzed by iron

专利号:CN-104892539-B
优先权日:2015-05-29
标 题:A new method for the synthesis of 2-arylbenzoxazole compounds catalyzed by iron

专利号:CN-117285454-A
优先权日:2023-10-16
标题:A kind of synthesis method of indole derivatives and benzodipyrrole derivatives